Fructose diphosphate sodium liposome solid preparation and novel application thereof

The technology of sodium fructose diphosphate and sodium diphosphate lipid is applied in the field of sodium fructose diphosphate liposome and its preparation, which can solve the problems of low curative effect, poor absorption and the like, and achieves improvement of therapeutic index, reduction of drug toxicity and production technology simple effect
CN101874779AInactive Publication Date: 2010-11-03HAINAN MEILAN SMITH KLINE PHARMA

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HAINAN MEILAN SMITH KLINE PHARMA
Publication Date
2010-11-03
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a fructose diphosphate sodium liposome solid preparation and a novel application thereof. The fructose diphosphate sodium liposome solid preparation is prepared from fructose diphosphate sodium liposome and auxiliary materials, wherein the fructose diphosphate sodium liposome is prepared from fructose diphosphate sodium, lecithin, cholesterol and polyglycerin ester. The invention also provides the application of the fructose diphosphate sodium liposome solid preparation in improving the immunity of tumor patients undergoing chemotherapy. The fructose diphosphate sodium liposome can be prepared by adopting a thin-film dispersion technology to combine a certain amount of the lecithin, the cholesterol, the polyglycerin ester and the active component fructose diphosphate sodium, and is mixed with a certain amount of the auxiliary materials to prepare various solid preparations, so the invention can well solve the problems of poor in-vivo absorption degree and low curative effect, and obtains satisfactory technical effect.
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Claims

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