Chinese medicinal composition and preparation for relaxing bowel and preparation method thereof

A technology of laxative and traditional Chinese medicine preparations, applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as aggravating constipation, physical weakness of the elderly, and achieve fast onset of effect and easy swallowing. , the exact effect of curative effect

Active Publication Date: 2011-01-12
YANGTZE RIVER PHARM GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many scholars do not advocate the use of these laxatives, because they can aggravate constipation and make the elderly weaker after stopping the medicine

Method used

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  • Chinese medicinal composition and preparation for relaxing bowel and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] The preparation of embodiment 1 pharmaceutical capsule of the present invention

[0053] Raw material and dosage:

[0054] Cistanche 20g, radish seed 15g, cassia seed 15g, Atractylodes macrocephala 20g.

[0055] Preparation:

[0056] (1) Weigh each crude drug according to the above-mentioned dosage, first extract Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome, Semen Cassiae and Semen Radix with reflux of 10 times of ethanol twice for 1 hour and 2 hours respectively.

[0057] (2) Add the reflux extract of step (1) to anhydrous sodium sulfate for dehydration, let stand overnight, filter (80 mesh sieve) to obtain fatty oil, and dregs for subsequent use;

[0058] (3) Add the dregs of step (2) into Cistanche cistanche, decoct and extract twice, the first time for 1 hour, and the second time for 2 hours, the amount of water added is 10 times the amount, and the medicinal liquid obtained from the two extractions is mixed and spray-dried to obtain dry powder ...

Embodiment 2

[0061] Embodiment 2 capsule preparation of the present invention

[0062] Raw material and dosage:

[0063] Cistanche 10g, radish seed 20g, cassia seed 20g, Atractylodes macrocephala 10g.

[0064] Preparation:

[0065] (1) Weigh each crude drug according to the above-mentioned dosage, first extract Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome, Semen Cassiae and Semen Radix with reflux of 10 times of ethanol twice for 1 hour and 2 hours respectively.

[0066] (2) Add the reflux extract of step (1) to anhydrous sodium sulfate for dehydration, let stand overnight, filter (80 mesh sieve) to obtain fatty oil, and dregs for subsequent use;

[0067] (3) Add the dregs of step (2) into Cistanche cistanche, decoct and extract twice, the first time for 1 hour, and the second time for 2 hours, the amount of water added is 10 times the amount, and the medicinal liquid obtained from the two extractions is mixed and spray-dried to obtain dry powder for use;

[0068] (4)...

Embodiment 3

[0070] Embodiment 3 preparation of pharmaceutical granules of the present invention

[0071] Preparation:

[0072] Weigh the crude drug according to the following dosage, soak the crude drug of the present invention in water for 20-30 minutes according to the conventional method, add 3 times the amount of water to boil and keep boiling for 10-15 minutes, take the medicinal liquid; add 3 times the amount of water Keep boiling for 10-15 minutes after decocting, take the liquid medicine; mix and filter the two liquid medicines, concentrate to a thick paste with a relative density of 1.3-1.34, spray granulate, and dry. Subpackage.

[0073] Raw material and dosage:

[0074] Cistanche 25g, radish seed 10g, cassia seed 10g, Atractylodes macrocephala 25g.

[0075] Clinical experiment of the present invention and result analysis:

[0076] Case: A patient with constipation over the age of 55 was selected; the course of the disease was over 1 year; the stool was dry and hard to defec...

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Abstract

The invention relates to a Chinese medicinal composition for relaxing bowel. The composition is prepared from the following raw materials in part by weight: 10 to 25 parts of desertliving cistanche, 10 to 20 parts of radish seed, 10 to 20 parts of cassia seed and 10 to 25 parts of bighead atractylodes rhizome. The composition has the advantages of strict prescription, remarkable special effect, wide resource of raw materials and low cost. Because the prescription is simple, the quality control of the medicament is simple. The composition is prepared into the soft capsule formulation according to the characteristics of active ingredients and has accurate dosing; the contents can be very quickly absorbed by a human body in the form of liquid state after the capsules are disintegrated in vivo; and the soft capsules have the advantages of smooth surfaces, good mouthfeel and easy swallowing. The clinical primary pharmaceutical effect verifies that the composition has the advantages of definite therapeutic effect, rapid response, no toxic or side effect, safety, effectiveness, safe carrying and convenient eating for middle aged and elderly constipation patients. Clinical experiments verify that the effectiveness ratio reaches 100 percent and the composition has bright application prospect and market prospect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, specifically a traditional Chinese medicine composition for moistening bowels and laxatives for middle-aged and elderly patients with constipation, and a Chinese medicine preparation prepared by using the composition. The invention also relates to a preparation method of the Chinese medicine preparation. It belongs to the field of traditional Chinese medicine. Background technique [0002] Constipation is one of the common frequently-occurring diseases of middle-aged and elderly people. Many people may experience constipation in varying degrees as they grow older, which brings great harm to the physical and mental health of the elderly. The incidence rate can reach 20-30%. If constipation is not corrected for a long time and harmful substances in the rectum cannot be eliminated in time, it will have adverse effects on the human body. Constipation in the elderly can induce and aggrava...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/64A61P1/10
Inventor 杨洁郭代红刘皈阳金道山李欣陆璐陆军章徐元杰
Owner YANGTZE RIVER PHARM GRP CO LTD
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