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Composition of tall gastrodia tuber and lecithin, and preparation method thereof

A technology of lecithin and a composition is applied in the field of health care and can solve the problems of lack of more targeted methods and means, memory loss, decreased thinking ability and the like

Active Publication Date: 2012-06-27
陕西医药控股医药研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At this stage, there are no targeted methods and means for diagnosing memory and thinking ability decline, etc., that is to say, it is difficult to obtain specific data to prove what causes memory decline or thinking ability decline

Method used

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  • Composition of tall gastrodia tuber and lecithin, and preparation method thereof
  • Composition of tall gastrodia tuber and lecithin, and preparation method thereof
  • Composition of tall gastrodia tuber and lecithin, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] 1) Grind 3000g of Gastrodia elata, then add 24kg of ethanol with a volume concentration of 60%, reflux extraction twice, filter, combine the extracts, concentrate under reduced pressure to a thick paste, dry the thick paste at 60-80°C in vacuum, and dry the dry matter Pulverize and pass through a 100-mesh sieve to obtain about 280g of Gastrodia elata extract;

[0029] 2) Mix and dissolve 800g of PEG400 and 100g of PEG4000, then add 800g of soybean lecithin (Henan Xuchang Biological Products Co., Ltd.), stir and mix well, then add Gastrodia elata extract powder, pass through a colloid mill and mix well;

[0030] 3) The fully mixed gastrodia elata and lecithin composition is prepared into soft capsules through a soft capsule process, packaged and inspected.

Embodiment 2

[0032] 1) Grind 3000g of Gastrodia elata, add 24kg of ethanol with a volume concentration of 40%, reflux extraction twice, filter, combine the extracts, concentrate under normal pressure into a thick paste, and dry the thick paste under microwave vacuum at 20-50°C. Pulverize to obtain about 300g of Gastrodia elata extract;

[0033] 2) Add Gastrodia elata extract and 600g egg yolk lecithin into 1000ml of absolute ethanol and mix evenly, then recover the ethanol under low temperature (30-50°C) under reduced pressure.

[0034] 3) Dissolve 30g of beeswax with 1000g of soybean oil, add 900g of the mixture of lecithin and Gastrodia elata extract, and 0.2g of vitamin E, mix well, and pass through a colloid mill.

[0035] 4) Prepare the well-mixed gastrodia elata and lecithin composition into hard capsules through a hard capsule process, pack and inspect.

Embodiment 3

[0037] 1) 4000g of Gastrodia elata was crushed, then 40kg of ethanol with a volume concentration of 70% was added, extracted twice under reflux, filtered, combined extracts, recovered ethanol, and concentrated into a thick paste with a specific gravity of 1.30 (60°C). Get about 400g of the quality of dry extract;

[0038] 2) 600g of egg yolk lecithin, 450g of starch, Gastrodia elata extract, 0.2g of vitamin E and 100ml of ethanol are made into a soft material, granulated, dried, and then granulated to make granules;

[0039] 3) Then add 200g of magnesium stearate and mix, press the tablet weight (500mg or 1000mg) according to the specification tablet weight (500mg or 1000mg) by tableting process, pack, test.

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Abstract

The invention discloses the composition of tall gastrodia tuber and lecithin, and a preparation method thereof. The composition is prepared by mixing tall gastrodia tuber extract and the lecithin according to the mass ratio of 10:90 to 95:5, wherein the tall gastrodia tuber extract is whole tall gastrodia tuber powder or the alcohol extract of medicinal parts of the tall gastrodia tuber; the lecithin is egg yolk lecithin or soybean lecithin; and the alcohol extract is powder obtained by refluxing and extracting the whole tall gastrodia tuber powder or the alcohol extract of the medicinal parts of the tall gastrodia tuber by using 30 to 90 volume percent ethanol, collecting extract, concentrating the extract into paste and drying and crushing the paste. The composition is prepared by compounding the tall gastrodia tuber extract and the lecithin, is rational in formula, advanced in process, safe and effective, has complementary functions and the effects of invigorating the brain and tolerating hypoxia, supplements neural transmitting substances by the lecithin, and simultaneously has the central nervous system depression function of the tall gastrodia tuber extract and the functionsof improving the anaerobic condition of a human body, particularly the brain, and protecting the brain from damage.

Description

technical field [0001] The invention belongs to the technical field of health care and relates to brain health care products, in particular to a composition of Gastrodia elata and lecithin and a preparation method thereof. Background technique [0002] It is generally believed that the human brain begins to decline after the age of 15-20, the memory before the age of 25 is at its peak, and the cognitive function before the age of 35-45 maintains a certain level. It is a natural physiological phenomenon that the brain begins to mutate and shrink from the age of 45, especially over the age of 65. As the brain shrinks, so does memory. After people reach middle age, the substance related to memory in the brain - acetylcholine will gradually decrease. This is because the ability of the brain to use choline to produce acetylcholine is gradually declining and weakened. For example, in patients with Alzheimer's disease, the ability to synthesize acetylcholine Compared with normal ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61P25/00A61K31/685
Inventor 肖志强何俊婷朱骤海余李敏杨建刚张琳张建辉
Owner 陕西医药控股医药研究院有限公司
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