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Celery seed extract composition and preparation method thereof

A technology of celery seed extract and composition, which is applied in the field of medicine, and can solve the problems that the stability of flavonoid components cannot meet the requirements, etc.

Active Publication Date: 2012-11-07
BEIJING HUMANWELL JUNWEI PHARM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a kind of liquid composition that can be used for the treatment of the celery seed ethanol extract of gout, and its preparation method, to overcome the stability of flavonoids component when celery seed ethanol extract is formulated into liquid composition Problems that do not meet the requirements

Method used

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  • Celery seed extract composition and preparation method thereof
  • Celery seed extract composition and preparation method thereof
  • Celery seed extract composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Example 1. Preparation of composition

[0065] The formulation of the example composition:

[0066]

[0067] The capsule shell formula when making soft capsules:

[0068]

[0069]

[0070] Prepare according to the following method:

[0071] (1) Preparation of capsule skin materials: Measure pure water and put it into a gelatinization tank, heat it to 70-80℃ in a water bath, add gelatin, add glycerin, methyl paraben and titanium dioxide after dissolution, mix well, keep the temperature at 70 -80℃, vacuum degassing, keep warm at 55-60℃ for later use.

[0072] (2) Preparation of the liquid composition: Weigh the celery seed extract and the diluent that has been added to the suspending agent, mix well, then add additives such as antioxidants, stir evenly, and stand at room temperature; obtain the liquid composition of the present invention , Half of which are packed in oral liquid bottles, and half are used in the following step (3) to prepare soft capsules;

[0073] (3) Transfer t...

Embodiment 2

[0074] Example 2. Preparation of the composition

[0075] The formulation of the example composition:

[0076]

[0077] The capsule shell formula when making soft capsules:

[0078]

[0079] Prepare according to the following method:

[0080] (1) Preparation of capsule skin materials: Measure pure water and put it into a gelatinization tank, heat it to 70-80℃ in a water bath, add gelatin, add glycerin, methyl paraben and titanium dioxide after dissolution, mix well, keep the temperature at 70 -80℃, vacuum degassing, keep warm at 55-60℃ for later use.

[0081] (2) Preparation of the liquid composition: Weigh the celery seed extract and the diluent that has been added to the suspending agent, mix well, then add additives such as antioxidants, stir evenly, and stand at room temperature; obtain the liquid composition of the present invention , Half of which are packed in oral liquid bottles, and half are used in the following step (3) to prepare soft capsules;

[0082] (3) Transfer the pr...

Embodiment 3

[0083] Example 3. Preparation of the composition

[0084] The formulation of the example composition:

[0085]

[0086] The capsule shell formula when making soft capsules:

[0087]

[0088] Prepare according to the following method:

[0089] (1) Preparation of capsule skin materials: Measure pure water and put it into a gelatinization tank, heat it to 70-80℃ in a water bath, add gelatin, add glycerin, methyl paraben and titanium dioxide after dissolution, mix well, keep the temperature at 70 -80℃, vacuum degassing, keep warm at 55-60℃ for later use.

[0090] (2) Preparation of the liquid composition: Weigh the celery seed extract and the diluent that has been added to the suspending agent, mix well, then add additives such as antioxidants, stir evenly, and stand at room temperature; obtain the liquid composition of the present invention , Half of which are packed in oral liquid bottles, and half are used in the following step (3) to prepare soft capsules;

[0091] (3) Transfer the pr...

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Abstract

The invention relates to a celery seed extract composition and a preparation method thereof. The composition contains 30-90 parts by weight of celery seed extract, 10-70 parts by weight of thinner, 0.01-1 part by weight of antioxidant, and optional suspending agent, surfactant and preservative. The invention further relates to a soft capsule preparation containing the composition or an oral liquid preparation containing the composition, and the preparation method of the composition or a preparation method of the preparation. The composition is reasonable in types of accessories and a main drug, reasonable in matching dose and convenient to administrate, and has the advantages of stability, safety, rapid response, high bioavailability, small side effects, small administration dose and the like. The preparation method has the characteristics of simple process and stable product quality, and is easy to control.

Description

Technical field: [0001] The invention belongs to the field of medicine, and relates to a composition of celery seed extract and a preparation method thereof, and in particular to a composition made of celery seed ethanol extract that can be used to treat gout, such as oral liquid or soft capsule, and preparation thereof method. Background technique: [0002] Celery seed is the seed of Apium graveolens L., a plant of the Umbelliferae family. Celery, also known as parsley and dry celery, is recorded in "Lugan Rock Materia Medica". It is an annual or biennial herbaceous plant in the Umbelliferae family and is cultivated throughout the country and the world. Celery seed is often used in condiments and foods. Celery seed tea has a significant effect on promoting sleep. Its extract has a contraction effect on pregnant and non-pregnant uterus and can be used to treat dysmenorrhea. Chinese medicine believes that celery seed has the functions of dispersing Qi, reducing swelling, diuresi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K131/00
Inventor 李莉娥蔡正军伊进朝陈海生高永良
Owner BEIJING HUMANWELL JUNWEI PHARM TECH CO LTD
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