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Pubescent holly root saponin and flavonoid capsule for treating transient ischemic attack

A technology of transient cerebral ischemia and hairy holly saponone, which is applied in the field of medicine to achieve remarkable effects, simple prescriptions, and scientific and reasonable compatibility

Inactive Publication Date: 2011-05-18
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can effectively solve the problem of treating transient ischemic attack

Method used

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  • Pubescent holly root saponin and flavonoid capsule for treating transient ischemic attack
  • Pubescent holly root saponin and flavonoid capsule for treating transient ischemic attack
  • Pubescent holly root saponin and flavonoid capsule for treating transient ischemic attack

Examples

Experimental program
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Effect test

Embodiment 1

[0011] In the implementation of the present invention, the capsule of the present invention is mixed together with the total flavonoids of Ilex radiata and total saponins in a weight ratio of 10:5, adding 10% microcrystalline fiber of the total weight of total flavonoids of Ilex radiata, total saponins and microcrystalline cellulose The element is packed into capsules and made. The total flavonoids and total saponins of Radix Ilex pubescens are obtained by adding 800 g of Radix Radix Radix to 800 g of medicinal materials and adding 10 times the amount of ethanol with a mass concentration of 70%, soaking for 30 minutes, extracting for 1 hour, and recovering the medicinal solution. Add 8 times the amount of ethanol with a mass concentration of 70% to the dregs, soak for 30 minutes, extract for 1 hour, combine the first and second medicinal liquids; adjust the pH of the two medicinal liquids to 4-5, and then open the large hole Resin: flushing the resin column with 35% ethanol to ...

Embodiment 2

[0013] In an embodiment of the present invention, the capsule of the present invention is mixed together with total flavonoids and total saponins of Ilex radiata with a weight ratio of 10:6, and 10- 20% starch and 1% magnesium stearate are packed into capsules and made, and the total flavonoids and total saponins of Radix radiata 800g medicinal materials plus 10 times the mass concentration of 70% ethanol are soaked 30min, extract for 1h, and recover the liquid medicine. Add 8 times the amount of ethanol with a mass concentration of 70% to the dregs, soak for 30 minutes, extract for 1 hour, combine the first and second medicinal liquids; adjust the pH of the two medicinal liquids to 4-5, and then open the large hole Resin: flushing the resin column with 35% ethanol to obtain the total flavonoids of Ilex radiata, and then flushing the resin column with ethanol with a mass concentration of 70% to obtain the total saponins of Ilex radiata.

Embodiment 3

[0015] In an embodiment of the present invention, the capsule of the present invention is mixed together with total flavonoids of Radix Ilexin and total saponins at a weight ratio of 10:7, and 40%-50% of the total weight of Radix Radix Radix Total flavonoids, total saponins and dextrin is added. Dextrin is packed into capsules, and the total flavonoids and total saponins of Ilex pubescens are prepared by taking 800 g of Ilex pubescens and adding 10 times the amount of ethanol with a mass concentration of 70%, soaking for 30 minutes, extracting for 1 hour, and recovering the medicinal solution. Add 8 times the amount of ethanol with a mass concentration of 70% to the dregs, soak for 30 minutes, extract for 1 hour, combine the first and second medicinal liquids; adjust the pH of the two medicinal liquids to 4-5, and then open the large hole Resin: flushing the resin column with 35% ethanol to obtain the total flavonoids of Ilex radiata, and then flushing the resin column with eth...

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Abstract

The invention relates to a pubescent holly root saponin and flavonoid capsule for treating transient ischemic attack, which can effectively solve the problem of treating the transient ischemic attack. The capsule is prepared by the steps of mixing pubescent holly root general flavone and total saponins in the weight ratio of 10:(5-7); adding an auxiliary material accounting for 10 to 50 percent of the total weight of the pubescent holly root general flavone, the total saponins and the auxiliary material; and loading in a capsule, wherein the auxiliary material is one or a mixture of two of microcrystalline cellulose, starch, magnesium stearate or dextrin. The capsule has a simple formula, scientific and reasonable compatibility and remarkable effect, and is creation of the pubescent holly root on medicinal value.

Description

1. Technical field [0001] The invention relates to medicine, in particular to a holly saponone capsule for treating transient ischemic attack. 2. Background technology [0002] Transient ischemic attack (TIA) refers to a transient neurological dysfunction syndrome caused by local transient insufficient blood supply of the internal carotid artery system or vertebrobasilar artery system. Sexuality and recurrence are its main clinical features, and it is more common in middle-aged and elderly people over 50 years old. TIA is an early clinical manifestation of ischemic stroke, and the more frequent the TIA, the greater the risk of stroke. 10% to 37% of TIA patients can develop complete stroke within 3 to 5 years, from the first TIA attack to the development of stroke, most of them occur within the first year after TIA, and within the first 2 months after TIA The risk of stroke is highest. The incidence of stroke in patients with TIA after 1 year was 16 times higher than that ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K9/48A61P9/10
Inventor 苗明三白明苗艳艳
Owner HENAN UNIV OF CHINESE MEDICINE