Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Powder with antibacterial and haemostatic effects and preparation method and applications thereof

A hemostatic powder and reactor technology, which is applied in the medical and health field, can solve the problems of difficult uniform dispersion, weak bactericidal ability, weak oxidizing ability, etc., and achieve the effects of favorable dispersion, strong bactericidal ability and rapid absorption.

Active Publication Date: 2013-07-24
SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this antibacterial and hemostatic powder granule has following deficiency: (1) the silver that is adsorbed on the rush surface is the microparticle silver of zero valence, can only form the silver ion (Ag + ) to sterilize, the monovalent silver ion has weak bactericidal ability due to weak oxidation; (2) the raw material used is silver nitrate, and the nitrate group harmful to human body has not been removed during the preparation process; (3) the product When the powder is used for hemostasis on the patient's wound surface, it is easy to form agglomerates due to the absorption of water in the blood, which is difficult to disperse evenly and has a small amount of water absorption.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Powder with antibacterial and haemostatic effects and preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] A preparation method of bactericidal hemostatic powder, comprising the following steps:

[0048] (1) Take silver peroxide (Ag 2 o 2 ), put into the reactor, add distilled water, after stirring for 15 minutes, add sulfuric acid dropwise, every 60 minutes of stirring, detect the pH value of the solution, make the pH value to 2, clarify for 2 hours, adjust the silver ion mass fraction to be 0.01% , adding mass fraction in the reactor is 0.3% hydrogen peroxide, stirred for 2 hours, and obtained the mother liquor containing high-valence silver ions;

[0049] (2) get 1kg length and be the rush grass of 2mm, put into the reactor that 100kg contains the mother liquor of high-valence state silver ion after wrapping with screen cloth, stir until rush rush all soaks into the solution containing high-valence state silver ion, place After 10 hours, silver-loaded rushes were prepared;

[0050] (3) taking out the silver-loaded rushes from the screen cloth, squeezing them dry, putti...

Embodiment 2

[0053] A preparation method of bactericidal hemostatic powder, comprising the following steps:

[0054] (1) Take silver oxide (Ag 2 0), put into the reactor, add distilled water, after stirring for 60 minutes, add sulfuric acid dropwise, every 10 minutes of stirring, detect the pH value of the solution, make the pH value to 3.5, clear 2 hours, adjust the silver ion mass fraction to be 1 %, add massfraction in reactor and be 10% hydrogen peroxide, stir 1 hour, make the mother liquor containing high valence state silver ion;

[0055] (2) Get 2kg of rushes with a length of 30mm, put them into a reactor containing 100kg of mother liquor containing high-valence silver ions after wrapping them with screen cloth, stir until the rushes are all soaked into the solution containing high-valence silver ions, and place for 2 hours , to prepare silver-loaded rushes;

[0056] (3) taking the silver-loaded rush out of the screen cloth, squeezing it dry, putting it into an oven, and drying it...

Embodiment 3

[0059] A preparation method of bactericidal hemostatic powder, comprising the following steps:

[0060] (1) Take silver peroxide (Ag 2 o 2 ), put into the reactor, add distilled water, after stirring for 40 minutes, add sulfuric acid dropwise, every stirring for 30 minutes, detect the pH value of the solution, make the pH value to 3, clarify for 6 hours, adjust the silver ion mass fraction to be 0.3% , adding mass fraction in the reactor is 3% hydrogen peroxide, stirred for 1.5 hours to obtain a mother liquor containing high-valence silver ions;

[0061] (2) get 2kg length and be the rush grass of 10mm, soak through 50% ethanol earlier, moisten and squeeze dry process, then put into the reactor that 100kg contains the mother liquor of high-valence silver ion after wrapping with screen cloth, stir Until the rushes are completely soaked into the solution containing high-valent silver ions, stir for 0.5 hours further, and place for 8 hours to obtain silver-loaded rushes;

[00...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
lengthaaaaaaaaaa
Login to View More

Abstract

The invention provides powder with antibacterial and haemostatic effects and a preparation method and applications thereof. The powder with antibacterial and haemostatic effects comprises silver-carrying aquatic grass, medical acrylic resin and calcium bentonite, wherein silver-carrying aquatic grass is aquatic grass adsorbed with high-valence silver ions. The powder has the following benefits: (1) the powder has strong antibacterial effect; (2) the powder has long-lasting antibacterial effect; (3) the powder can rapidly absorb the water in the blood on the surface of wound, and promote accelerated coagulation of the blood on the surface of wound within a few seconds; and the powder does not agglomerate, which is favorable for dispersion and convenient in application; (4) the powder contains calcium ions which is helpful for wound healing; and (5) the powder has no irritation to human body.

Description

technical field [0001] The invention relates to the medical and health field, in particular to a bactericidal hemostatic powder and a preparation method and application thereof. Background technique [0002] In daily life, people often encounter situations that require sterilization and hemostasis of traumatic wounds or surgical wounds. Wound coverings are usually gauze-like dressings processed from materials such as cotton, burlap, non-woven fabrics, or linen. However, when these gauze dressings are used, wound healing is slow, frequent dressing changes are required, and wound bacterial infection is easy to occur, which brings great misery to patients. [0003] The Chinese patent with publication number CN1123665A discloses an antibacterial and hemostatic powder granule made of long-acting broad-spectrum antibacterial granules. The invention can be directly applied to the wound surface and is convenient to use. But this antibacterial and hemostatic powder granule has fol...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/40A61L15/24A61L15/18A61L15/44A61K33/38A61K47/46A61P7/04A61P17/02
Inventor 蒋华德高培军王红梅曾孔仙
Owner SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com