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Applying shear stress for disease treatment

A technology of shear stress, therapeutic agent, applied in the field of disease treatment, can solve problems such as difficulties

Inactive Publication Date: 2011-08-31
HRD CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a result, even when appropriate drugs are available or will be available, delivering drugs to the brain to manage various brain disorders (eg, meningitis, epilepsy, neurological trypanosomiasis, progressive multifocal leukoencephalopathy) is difficult

Method used

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  • Applying shear stress for disease treatment
  • Applying shear stress for disease treatment
  • Applying shear stress for disease treatment

Examples

Experimental program
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Embodiment Construction

[0028] As used herein, the term "therapeutic fluid" refers to a dispersion comprising at least one therapeutically effective substance. Some examples of these substances are neurological drugs, anti-inflammatory drugs, anti-cancer drugs, antibiotics, therapeutic gases (such as ozone), viral vectors, genes, proteins, polymers, liposomes, organic particles, inorganic particles.

[0029]As used herein, the term "dispersion" means a liquefied mixture comprising at least two distinguishable substances (or "phases") that may or may not readily mix and dissolve together. A "dispersion" herein includes a continuous phase (or "matrix") in which discrete droplets, gas bubbles, and / or particles of other phases or substances are contained. Dispersions herein may refer to: foams comprising gas bubbles suspended in a continuous liquid phase; emulsions in which droplets of a first liquid are dispersed throughout a continuous phase comprising either a miscible or an immiscible second liquid;...

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PUM

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Abstract

Herein disclosed is a system for applying shear stress ex-situ to a fluid. In some embodiments, the system comprises a shear device; and at least one device configured for intravenous administration of the fluid to a patient, the devices defining a fluid passage configured to be sterilized and maintained sterile during use, the fluid comprising at least one therapeutic fluid, blood, or a combination thereof. The shear device of the system is in fluid communication with the at least one device configured for intravenous administration of the fluid to a patient. Herein also disclosed is a method of preparing a fluid for intravenous administration to a patient.

Description

[0001] Statement Regarding Federally Sponsored Research or Development [0002] none. technical field [0003] The present invention mainly relates to the treatment of diseases. More specifically, the present invention relates to the use of shearing devices to apply appropriate shear stresses to therapeutic fluids and / or blood to treat disease. Background technique [0004] Due to the complexity of the human body and the complications of various diseases, disease management has always been the most challenging and active field in medicine. Disclosed herein is a system and method for applying shear stress to treat disease. Some examples of diseases are brain diseases including meningitis, epilepsy, neurological trypanosomiasis, progressive multifocal leukoencephalopathy. Further examples of diseases are cancers including malignancies, benign tumors, metastases and hematological malignancies. Because of the breadth of this field, brain disease and cancer are used as exampl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/14A61M37/00
CPCA61M2206/16A61M1/36A61M5/142A61K9/0019B01F27/2711A61M37/00A61M5/168A61M2205/3334A61M2205/3368
Inventor 阿巴斯·哈桑雷福德·G·安东尼格雷戈里·G·博尔西格阿齐兹·哈桑
Owner HRD CORP