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Method for carrying out automatic classified counting on cells in human blood

An automatic classification and cell technology, applied in the field of blood analysis, can solve the problems of inability to adjust and low boundary efficiency, and achieve the effect of overcoming low boundary efficiency

Inactive Publication Date: 2012-01-25
无锡荣兴科技有限公司
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Problems solved by technology

[0008] The purpose of the present invention is to overcome the deficiencies in the prior art, and to provide a method for automatically classifying and calculating cells in human blood, which can perform adaptive classification based on data characteristics, and can automatically Adjust the boundaries of each category, overcome the defect that fixed classification cannot be adjusted according to blood characteristics, and overcome the defect of low efficiency of manual adjustment of boundaries, and can be used in automatic blood cell analyzers for rapid analysis

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  • Method for carrying out automatic classified counting on cells in human blood
  • Method for carrying out automatic classified counting on cells in human blood
  • Method for carrying out automatic classified counting on cells in human blood

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Embodiment Construction

[0026] The present invention will be further described below in conjunction with the accompanying drawings.

[0027] The invention provides a method for automatically classifying and calculating cells in human blood, which is implemented by computer software, and the algorithm flow is as follows figure 2 As shown, it mainly includes the following steps:

[0028] (1) Generate a two-dimensional scatter plot from two one-dimensional data;

[0029] (2) smoothing the above-mentioned two-dimensional scatter diagram, so that the points at the boundary of this class are continuous with the main part of this class, and eliminate distant discrete points;

[0030] (3) Based on the smoothed two-dimensional scatter diagram, cluster and find the class center, classify and label the cells;

[0031] (4) Count the number of cells at the position with the same label, and add them together to get the number of cells in this class; add up all effective values ​​in the scatter plot to get the t...

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Abstract

The invention relates to a method for carrying out automatic classified counting on cells in human blood, which comprises the following steps: (1) generating a two-dimensional scatter diagram on two one-dimensional data; (2) carrying out smooth treatment on the two-dimensional scatter diagram so as to make points at the border of the class and the main body part of the class continuous, and eliminating distant discrete points; (3) clustering and searching a class center by taking the two-dimensional scatter diagram after smooth treatment as a foundation, and classifying and labeling the cells; (4) counting the cells in the positions with the same label, and calculating the percentage of each class of cells accounting for the total cells. The method disclosed by the invention can be used for carrying out adaptive classification based on data characteristics, the border of each class can be automatically adjusted according to the characteristics of the scatter diagram of a blood sample, the defects that fixed classification cannot be adjusted according to blood characteristics and the efficiency of manual border adjustment is low are overcome, and the method can be used in an automatic blood cell analyzer for rapid analysis.

Description

technical field [0001] The invention relates to a blood analysis technology, in particular to a method for automatically classifying and calculating cells in human blood. Background technique [0002] There are three types of blood cells in human blood, namely red blood cells, white blood cells and platelets. There are five types of white blood cells: eosinophils, neutrophils, basophils, lymphocytes, and monocytes. In the early days, the analysis of blood cells relied on manual identification under a microscope through morphology. Later, Coulter invented an instrument that can automatically analyze blood cells. The analysis principle is: particles flow through a small hole filled with liquid. Time will cause the conductivity at both ends of the hole to change, and the rate of change of conductivity is proportional to the volume of the particle. Because there are differences in the volume of blood cells, the volume of white blood cells is larger than that of red blood cells...

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Application Information

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IPC IPC(8): G01N15/10
Inventor 楚建军
Owner 无锡荣兴科技有限公司
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