Preparation method and quality control method of heartleaf houttuynia herb injection

A technology of Houttuynia cordata injection and quality control method, which is applied in the field of medicine, and can solve problems such as failure to prepare, waste of Houttuynia cordata resources, and limited solubilization effect of Tween-80
CN102335271AInactive Publication Date: 2012-02-01HUNAN ZHENGQING PHARM GRP CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HUNAN ZHENGQING PHARM GRP CO LTD
Publication Date
2012-02-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a preparation method and quality control method of heartleaf houttuynia herb injection. The preparation method of the injection comprises the following steps: distilling whole plant of fresh heartleaf houttuynia herb with steam; collecting initial distillate; re-distilling to collecting re-distillate; adding an osmotic pressure regulating agent and a beta-cyclodextrin derivative; regulating the pH value; filtering; encapsulating; and sterializing to prepare the injection. According to the preparation, preparation of the heartleaf houttuynia herb injection without tween-80 is realized for the first time, the prepared heartleaf houttuynia herb injection does not have haemolysis, has high concentration of effective components, can be used for intramuscular injection or intravenous drip, and is safer in use and better in stability. The quality control method comprises a method of identifying methylnnonylketone and decanoyl acetaldehyde and a method of detecting the content of the methylnnonylketone, so that the product quality can be effectively controlled.
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Description

technical field

[0001] The invention relates to a preparation method and a quality control method of an injection, in particular to a preparation method and a quality control method of a Houttuynia cordata injection containing a β-cyclodextrin derivative, which belongs to the field of medical technology. This application is Divisional application of Patent No. 200410037630.2. Background technique

[0002] The current production method of Houttuynia cordata injection is to take fresh whole herb of Houttuynia cordata for steam distillation, collect the initial distillate, then redistill, collect the double distillate, add sodium chloride and Tween-80, mix well, It is obtained by adding water for injection to the prepared amount, filtering, potting, and sterilizing. It has antibacterial, antiviral, anti-inflammatory and other effects, can improve the immune function of the body, and belongs to the national medical insurance class A drug.

[0003] Houttuynia cordata injection ...

Claims

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