Traditional Chinese medicinal composition for treating transmissible gastroenteritis of swine, feed, preparation method and application thereof
A composition and infectious technology, applied in the field of traditional Chinese veterinary medicine, can solve the problems of unsatisfactory treatment effect, poor formula, single variety, etc., and achieve the effect of improving the body's immunity, no toxic side effects, and no drug resistance
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[0070] The present invention also provides the preparation method of the above-mentioned traditional Chinese medicine composition for treating porcine transmissible gastroenteritis, which comprises:
[0071] In the first step, each component is mixed and pulverized according to the stated ratio;
[0072] In the second step, the pulverized mixture obtained in the first step is added to water for decoction, left to stand, and filtered;
[0073] In the third step, the material obtained by filtering in the second step is concentrated under reduced pressure, dried to make a dry paste, and crushed into a powder of 50 mesh to 100 mesh to obtain the traditional Chinese medicine composition of the invention.
[0074] In the second step, the quality of the added water is 3 to 4 times that of the pulverized mixture in the first step, the decoction time is 2 hours to 4 hours, the number of decoctions is preferably 2 to 4 times, and the standing time is preferably 24 hours to 36 hours.
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Embodiment 1
[0093] Embodiment 1 The acute toxicity test of Chinese medicine composition of the present invention to mice
[0094] 1. Test animals
[0095] SPF grade healthy KM mice, 40, half male and half male, weighing 20-25 g; purchased from the Experimental Animal Center of Hubei Academy of Traditional Chinese Medicine
[0096] 2. Experimental drug
[0097] 50g Coptis chinensis, 21g Sophora flavescens, 11g Woody Fragrance, 18g Qinpi, 21g Chunpi, 14g Honeysuckle, 12g Pulsatilla, 10g Poria, 12g Coix Seed, 10g Gallnut, 9g Ume, 12g Codonopsis, 12g Astragalus, 8g Angelica, 7g Chenpi, 9g licorice, 5g corydalis, 4g hawthorn, 2g gallinaceous gold and 2g Burnet are mixed and pulverized; the pulverized mixture is added to 800g water and decocted 3 times, each time for 3 hours, standing for 36 hours, and filtered; The substance is concentrated under reduced pressure, dried to make a dry paste, and crushed into a 50-mesh powder to obtain the traditional Chinese medicine composition of this metho...
Embodiment 2
[0122] Embodiment 2 The long-term toxicity test of Chinese medicine composition of the present invention to test piglet
[0123] Take 20 healthy test piglets (provided by a pig farm in Hefei City, Anhui Province), half male and half male, long-term drug administration for 7 weeks, and carry out long-term toxicity test. The results show that the general condition, growth and development, blood routine, liver and kidney of all test pigs There were no abnormal changes in function and other indicators, and no pathological changes were found in histopathology and gross autopsy.
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