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Traditional Chinese medicinal pain-relieving plaster
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A traditional Chinese medicine, the technology of making strychnids, applied in the directions of non-central analgesics, antipyretics, drug combinations, etc. Curative effect
Inactive Publication Date: 2014-08-27
LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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But its disadvantage is that it is easy to tolerate, and most patients need to increase the dose continuously. In addition, it is not satisfactory in terms of improving the quality of life and reducing adverse reactions.
However, most of the currently clinically applied painkillers for external use are large-scale prescriptions with many flavors and unclear effects. A large amount of animal drugs are often used, which has poor absorption and is prone to sensitization. Patients often experience local redness, swelling, itching, and blisters. , ulceration and other side effects, poor safety, seriously affecting the patient's continuous treatment and life
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Embodiment 1
[0018] A kind of traditional Chinese medicine pain-relieving patch, which is an extract made from 4 parts of Nuxyma chinensis, 10 parts of Corydalis Corydalis, 15 parts of Salvia miltiorrhiza, 6 parts of safflower, 10 parts of peach kernel, 12 parts of Qingfengteng, 3 parts of menthol and 5 parts of borneol , and then made into poultice, that is.
[0019] [experimental method]
[0020] 1 Hot plate analgesia
[0021] 60 female mice, weighing 18-22g, were placed on a hot plate pain measuring instrument at a temperature of 55-60.5°C, and the time from when the hind feet of the mice touched the hot plate to when they licked the hind feet was used as the pain threshold index. The pain threshold was measured on a hot plate pain measuring instrument, and 30 mice with a pain threshold within 5-30 s were selected and randomly divided into two groups with 15 mice in each group, which were divided into blank control group and drug treatment group. The normal pain threshold was measured...
Embodiment 2
[0035] Drugs: 3 parts of Strychnos chinensis, 12 parts of Corydalis Corydalis, 8 parts of Salvia miltiorrhiza, 10 parts of safflower, 12 parts of peach kernel, 8 parts of Qingfengteng, 4 parts of menthol, and 4 parts of borneol, made into patches.
[0036] Preparation method: extract nuxychia seeds, Corydalis Corydalis, and Qingfengteng through ethanol extraction, safflower, salvia miltiorrhiza, and peach kernels are extracted with water to make an extract, and menthol and borneol are ground into powder and added to the extract to make a cataplasm.
[0037] [experimental method]
[0038] 1 Hot plate analgesia
[0039] 60 female mice, weighing 18-22g, were placed on a hot plate pain measuring instrument at a temperature of 55-60.5°C, and the time from when the hind feet of the mice touched the hot plate to when they licked the hind feet was used as the pain threshold index. The pain threshold was measured on a hot plate pain measuring instrument, and 30 mice with a pain thresh...
Embodiment 3
[0053] Drugs: 6 parts of Nuxebra chinensis, 9 parts of Corydalis Corydalis, 12 parts of Salvia miltiorrhiza, 8 parts of safflower, 8 parts of peach kernel, 10 parts of Qingfengteng, 2 parts of menthol, and 3 parts of borneol, made into patches.
[0054] Preparation method: extract nuxychia seeds, Corydalis Corydalis, and Qingfengteng through ethanol extraction, safflower, salvia miltiorrhiza, and peach kernels are extracted with water to make an extract, and menthol and borneol are ground into powder and added to the extract to make a cataplasm.
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Abstract
A traditional Chinese medicinal pain-relieving plaster is characterized in that it is formed by steps of: preparing an extract by extracting the following raw materials of: by weight, 1-8 parts of processed Semen Strychni, 5-13 parts of corydalis tuber, 8-18 parts of red sage root, 5-12 parts of safflower, 5-13 parts of Peach Seed, 7-15 parts of orienavine, 1-9 parts of menthol and 1-8 parts of borneol, and coating the extract on a fabric carrier according to a set thickness or dosage. The invention relates to a traditional Chinese medicinal external-use patch which is prepared from pure traditional Chinese medicines and is used to treat ache caused by cancer itself and ache generated during the cancer treatment process. It is proved through animal experiments that the traditional Chinese medicinal pain-relieving plaster has a remarkable effect of easing pain. In addition, the plaster has advantages of simple composition, appropriate compatibility, definite therapeutic effect, convenient usage, high security, no side-effect and the like, and is a medicine which is desperately needed in clinic.
Description
Technical field: [0001] The invention is a traditional Chinese medicine external patch for treating the pain caused by cancer itself and the pain generated during cancer treatment. Background technique: [0002] With the change of life structure, the increasing pressure of work and study, and the acceleration of the pace of life, people's disease patterns have undergone great changes. The number of cancer patients has increased sharply, and its morbidity and mortality have also shown an increasing trend year by year in recent years. According to statistics, there are more than 10 million new cancer patients in the world every year, and about 1.8 million new cancer patients in my country every year. Cancer has become one of the killers that seriously endanger human health. Cancer pain is a common complication of advanced cancer. According to the statistics of the World Health Organization, the proportion of cancer patients worldwide with pain is 30% to 50%, and that of advanc...
Claims
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