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Novel medicament for treating cardio-cerebrovascular diseases and preparation method

A technology for cardiovascular and cerebrovascular diseases and new drugs, which is applied in the field of drug preparation for cardiovascular and cerebrovascular diseases, can solve the problems of inability to completely preserve the active ingredients of leeches, poor blood pressure, lipid-lowering and thrombolytic effects, absorption of new drugs and preparation methods, and the like. Clear pharmacology, hypolipidemic and thrombolytic effects, safe and reliable effects

Inactive Publication Date: 2012-11-28
龚元
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Solve the problem that the existing drugs for the treatment of cardiovascular and cerebrovascular diseases that use leeches as raw materials use non-blood-sucking leeches as medicines to make the effect of antithrombin poor and affect the curative effect; while enteric-coated capsules only use blood-sucking leeches as a single drug, which can lower blood pressure, lower lipids and dissolve blood. The suppository effect is relatively poor; and the existing preparation technology that adopts leech pharmaceuticals all cannot fully preserve many active ingredients of leech, which is unfavorable for the new drug and preparation method for the treatment of cardiovascular and cerebrovascular diseases of the patient's absorption problem

Method used

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Embodiment Construction

[0046] The new drug for the treatment of cardiovascular and cerebrovascular diseases and the preparation method are further described below by specific examples:

[0047]The new drug for treating cardiovascular and cerebrovascular diseases is obtained by first grinding medicinal materials leech, notoginseng and earthworm into powder, and then mixing the following components according to the weight percentage. The leeches are Hirudo nipponia Whitman, Hirudo pulchra Song, Poecilobdella manllillensis, Poecilobdella javanica, Poecilobdella hubeiensis Yang or Nanjing leech. A species of leeches (Poecilobdella nanjingensis sp.nov.).

[0048] The weight percent of the components is 8-12 parts of leech powder, 8-12 parts of notoginseng powder and 5-8 parts of earthworm powder. In order to achieve the best effect, the preferred solution of the present invention is 9-11 parts of leech powder, 9-11 parts of Panax notoginseng powder, and 6-7 parts of earthworm powder. The best solution ...

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Abstract

The invention relates to a novel medicament for treating the cardio-cerebrovascular diseases and a preparation method and belongs to the technical field of preparation of the novel medicament for treating the cardio-cerebrovascular diseases. According to the invention, blood-sucking leeches, panax pseudoginseng and earthworm are used as raw materials. According to the invention, by a special preparation process of carrying out liquid nitrogen flash freezing, low-temperature superfine grinding and freeze drying before sterilization on the raw materials, the grinding fineness can reach 1 to 10 micrometers, the active ingredients of the blood-sucking leeches can be stored to the greatest extent, the active ingredients can be sufficiently adsorbed by a patient, and the novel medicament has comprehensive effects of promoting circulation, removing stasis, resisting to coagulation, reducing the pressure, lowering lipid, resisting to platelet aggregation and dissolving thrombi and is safe and reliable to take. The invention solves the problems that an existing medicament which uses leeches as the raw materials and is used for treating the cardio-cerebrovascular diseases adopts non blood-sucking leeches as the medicine and adopts a conventional grinding method, so that the antithrombase effect is poor and the curative effect is influenced; and enteric capsules only adopt the single medicine of blood-sucking leech and have poor effects of reducing the pressure, lowering the lipid and dissolving the thrombi and the preparation process ensures the active ingredients of the leeches not to be completely stored and is unbeneficial for a patient to adsorb the active ingredients.

Description

technical field [0001] The invention relates to a new drug for treating cardiovascular and cerebrovascular diseases and a preparation method thereof, belonging to the technical field of preparation of drugs for cardiovascular and cerebrovascular diseases. Background technique [0002] Cardiovascular and cerebrovascular diseases have the characteristics of "high morbidity, high disability rate, high mortality rate, high recurrence rate, and many complications", and have become the number one killer in today's society that seriously threatens the health of almost everyone, including young people. . Hyperlipidemia, blood viscosity, atherosclerosis, high blood pressure, etc. are the culprits that cause cardiovascular and cerebrovascular diseases. At present, there are many medicines for treating cardiovascular and cerebrovascular diseases, but western medicines have serious side effects, and traditional Chinese medicines are mostly made by traditional techniques, and the active...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61K9/48A61K9/20A61K9/28A61P9/00A61P7/02A61P9/12A61P3/06A61K35/64A61K35/62
Inventor 龚元
Owner 龚元
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