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New use of Cordyceps sobolifera

A technique for the use of cicadae, which is applied in the field of new uses of cicadae, and can solve problems such as the lack of research and reports on the treatment of osteoporosis

Active Publication Date: 2014-09-10
ZHEJIANG BIOASIA PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, no matter whether it is natural cicadae or artificially cultivated cicadae, there is no research and report on its treatment of osteoporosis.

Method used

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  • New use of Cordyceps sobolifera

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The effect of embodiment 1 cicadae and cicadae fruiting body on MG63 bone cell proliferation

[0013] 1. Experimental materials and methods

[0014] 1.1 Experimental materials

[0015] In vitro culture of human bone cells MG63 (China Cell Bank Collection Cell Center); DMEM medium (Gibco, the United States); fetal bovine serum (Tianjin Haoyang Biological Products); trypsin (Amresco, the United States); dexamethasone, β-glycerophosphate Sodium, Phosphorylated Ascorbic Acid (ASAP), Thiazole Blue (Mrrr), Trypsin, Collagenase Type II, Sodium Naphthyl Phosphate (Sigma); flowers) (provided by Shanghai Pan-Asia Institute of Life Sciences). Before the experiment, extract with appropriate amount of water, filter, concentrate to a concentration of 1g / ml, and dilute before use.

[0016] 1.2 Method

[0017] 1.2.1 Cultivation of MG63 cells: Take out the frozen MG63 cells from liquid nitrogen, put them into warm water at 37°C quickly, and gently shake the cryopreservation tube to ...

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Abstract

The invention relates to a new use of Cordyceps sobolifera, especially a use of Cordyceps sobolifera or its fruiting body in preparing medicament proliferating osteocyte. The invention opens a new direction in the research for application of Cordyceps sobolifera, and brings gospel for patients with osteoporosis.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to the new application of cicadae flower. Background technique [0002] Osteoporosis is a common metabolic bone disease closely related to aging. Modern medicine believes that the occurrence of osteoporosis is related to the coupling imbalance between osteoblasts (osteoblast, OB) and osteoclasts. OB has The role of synthesizing and secreting collagen and glycoproteins that make up the bone matrix plays a major role in maintaining the stability of the body's internal environment, regulating physiological mechanisms and bone metabolism diseases. Promoting the proliferation of osteoblasts is the main way for Chinese medicine to prevent and treat osteoporosis. In vitro culture Osteoblasts are an important research method for drug efficacy evaluation and new drug development. [0003] Chinese medicine Cicada (Cordycepes cicadea), is a kind of medicinal insect fungus similar to Cordyceps sin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/066A61P19/10A61P19/08
Inventor 王玉芹谭悠久盖悦金赵燕孙长胜
Owner ZHEJIANG BIOASIA PHARMA CO LTD
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