Traditional Chinese medicine-assisted imaging preparation for ultrasonic image diagnosis, and preparation method thereof

An auxiliary imaging and ultrasonic image technology, applied in the direction of echo/ultrasonic imaging agents, pharmaceutical formulations, antibacterial drugs, etc., can solve the problems of strong gastric acid reaction, inapplicability, and no therapeutic effect, and achieve simple preparation process and short inspection time Short, no allergic reaction effect

Inactive Publication Date: 2014-05-28
夏玉萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, for B-ultrasound gastrointestinal imaging aids, the prior art has recorded an imaging aid prepared by mixing 80% of octopus fine powder and 20% of bletilla striata 100-mesh fine powder, which has astringent and acid-stopping effects on gastrointestinal diseases , but the disadvantage is that the strong echo light spot produced by the patient after taking the contrast agent is insufficient, the reflection effect is not good, and the layer of the stomach wall is not displayed clearly; after the patient takes the contrast agent, the gastric acid reaction is strong, and there is pain and discomfort. It is beneficial for contrast-enhanced ultrasound of the gastrointestinal tract, and this contrast agent cannot be used for patients with gastric bleeding
The prescription uses bitter barrels, which taste extremely bitter, so sucrose is used to improve the taste, and sucrose easily produces bubbles when it enters the gastric juice, which affects the imaging effect. In addition, the product of this invention has no therapeutic effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0058] When the prepared dosage form is a tablet, its preparation method includes the following steps:

[0059] The first step is to mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85 to 95% relative to 3 to 6 times the mass of the mixture, heat under reflux for 2 to 4 hours, extract 2 to 3 times, and combine The extract is filtered to obtain an alcohol extract, the alcohol extract is concentrated under reduced pressure, and recovered to have no alcohol smell; the medicinal residues obtained by filtration are then added with distilled water with 4 to 8 times the mass of the medicinal residues, and decocted for 1 to 3 hours. Decoct for 2 to 3 times, filter separately, combine the filtrates to obtain an aqueous extract, concentrate the aqueous extract under reduced pressure, mix with the concentrated solution of the alcohol extract obtained before, further concentrate under reduced pressure, remove the ...

Embodiment 1

[0071] Example 1: Tablets prepared by the present invention

[0072] Take Corydalis 150g, Cyanophora 140g, Angelica 170g, Panax notoginseng 170g, Atractylodes 150g, Gardenia 150g, Divine Comedy 230, Chenpi 250g, Green Calyx Plum 190g, August 70g, Daidaihua 110g, Pinellia 110g, Magnolia 130g , Poria 160g, calcined corrugated seeds 240g, calcined egg shell 200g, Huoxiang 110g and Perilla stem 130g.

[0073] Its preparation method comprises the following steps:

[0074] The first step is to mix the above-mentioned various raw materials of traditional Chinese medicine, add 5 times the mass of the mixture with ethanol with an alcohol concentration of 90%, heat under reflux for 3 hours, extract twice, combine the extracts, and filter to obtain an alcohol extract. The liquid is concentrated under reduced pressure, and recovered to have no alcohol smell; the medicinal residues obtained by filtration are respectively added with distilled water with 6 times of the quality of the medici...

Embodiment 2

[0077] Example 2: Powder prepared by the present invention

[0078] Take Corydalis 140g, Cyanophora 120g, Angelica 150g, Panax notoginseng 150g, Atractylodes 160g, Gardenia 160g, Divine Comedy 200, Chenpi 200g, Green Calyx Plum 160g, August 50g, Daidaihua 130g, Pinellia 100g, Magnolia 100g , 150g of Poria, 220g of calcined corrugated seeds, 180g of calcined egg shells, 100g of Huoxiang and 120g of Perilla stems.

[0079] Its preparation method comprises the following steps:

[0080] The first step is to mix Corydalis, Cyperus, Angelica, Panax notoginseng, Cangzhu, Gardenia, Divine Comedy, Chenpi, Pinellia, Magnolia, Poria, Huoxiang and Perilla stems in proportion, and the alcohol concentration is 70%~ 80% methanol is used as a solvent, and the percolation method is used to slowly permeate at a speed of 1ml per minute, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is pulverized into powder. The quality of the added meth...

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PUM

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Abstract

The invention provides a traditional Chinese medicine-assisted imaging preparation for ultrasonic image diagnosis. The traditional Chinese medicine comprises the raw material drugs: rhizoma corydalis, rhizoma cyperi, angelica sinensis, pseudo-ginseng, rhizoma atractylodis, fructus gardeniae, medicated leaven, tangerine peel, prunus mume, akebia fruit, seville orange flower, pinellia ternate, cortex magnoliae officinalis, poria cocos, calcined concha arcae, calcined egg shell, agastache rugosus and perilla stem. The traditional Chinese medicine-assisted imaging preparation has the beneficial effects of being safe to use, free from pain, wound, toxicity and anaphylactic reaction, short in examination time, high in imaging rate, convenient to use and low in cost, thus providing a new technology and a new method for the early accurate diagnosis of diseases, providing powerful basis for the clinical diagnosis and being an ideal auxiliary imaging preparation; and furthermore, the preparation technology is simple and practical.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine-assisted imaging preparation for ultrasonic image diagnosis and a preparation method thereof. Background technique [0002] Ultrasound image diagnosis is one of the important diagnostic methods in medicine. Ultrasound has three major effects on matter: First, mechanical action. Due to the huge ultrasonic energy, material particles often make high-frequency mechanical vibrations, resulting in crushing, agglomeration and stirring effects. The second is the effect of warming. When the ultrasonic wave acts on the material, its energy is absorbed by the material, thus increasing the temperature of the material. The third is cavitation. When the ultrasonic wave acts on the liquid, the areas with weak stress in the liquid (such as microscopic bubbles, etc.) become sparse due to the huge change in sound pressure. At this ti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K49/22A61K36/8905A61P1/04A61P1/00A61P31/04A61K35/56A61K35/54A61K35/57A61K35/618
Inventor 夏玉萍吕咸进王永萍王玉云管丽
Owner 夏玉萍
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