Device used for preserving lung under low temperature and ventilated situations during non-heart-beating-donor lung transplant

A lung and low temperature technology, applied in the field of auxiliary medical devices, can solve problems such as uneven distribution of lung preservation fluid, increased pulmonary vascular resistance, loss of benefits of endotracheal ventilation, etc., and achieve the effect of resisting NHBD lung heat ischemia injury

Active Publication Date: 2013-03-13
SHANGHAI PULMONARY HOSPITAL AFFILIATED TO TONGJI UNIV +1
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  • Summary
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  • Application Information

AI Technical Summary

Problems solved by technology

Donor lungs soaked in low-temperature lung preservation fluid maintain a semi-compressed state, which loses the benefits of ventilation, which will lead to an increase in pulmonary vascular resistance and uneven distribution of lung preservation fluid. The classic lung preservation method also has certain disadvantages, losing the benefits of endotracheal ventilation

Method used

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  • Device used for preserving lung under low temperature and ventilated situations during non-heart-beating-donor lung transplant
  • Device used for preserving lung under low temperature and ventilated situations during non-heart-beating-donor lung transplant

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Embodiment Construction

[0015] The invention can not only realize the perfusion and soaking of the low-temperature lung preservation solution for the lungs, but also can perform intratracheal ventilation sequentially, and combine their respective advantages to improve the quality of the NHBD lungs. Specific use can be divided into three stages, as shown in Figure 2.

[0016] First, the donor lung receives low-temperature lung preservation solution perfusion, rapid cooling, and protection of vascular endothelial cells.

[0017] The donor opens the chest to take out the cardiopulmonary complex. After taking it out, relax the elastic opening 4 above the medical elastic rubber bag 1 and place it in the cardiopulmonary complex. The medical elastic rubber bag 1 is provided with a central fixing bracket 7 which is Used to support the donor cardiopulmonary complex, the fixing ring 6 is located at the end of the fixing bracket 7, which can fix the left and right bronchus, so that the cardiopulmonary complex is saf...

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Abstract

The invention belongs to the technical field of auxiliary medical devices, and concretely relates to a device used for preserving a lung under low temperature and ventilated situations during a non-heart-beating-donor (NHBD) lung transplant. The device comprises a medical elastic rubber bag and an outer case, wherein the medical elastic rubber bag is used for placing a complex of the heart and the lung, and is provided with an inlet and an outlet for a low-temperature lung preservation solution, a central fixing support therein and a temperature sensor on an inner wall; the medical elastic rubber bag is arranged in the outer case; mixtures of ice and water are arranged between the outer case and the medical elastic rubber bag and can synergistically maintain the low-temperature state of the medical elastic rubber bag. In addition, two tee pipe joints are provided for respectively connecting the inlet and the outlet of the low-temperature lung preservation solution, left and right ventricular catheters and internal space of the medical elastic rubber bag. The device provided by the invention not only can realize filling and immersing of the low-temperature lung preservation solution, but also can sequentially ventilate in tracheae, thereby combining respective advantages, synergistically confronting warm ischemia injury of NHBD lung, and improving quality of the NHBD lungs.

Description

Technical field [0001] The invention belongs to the technical field of auxiliary medical devices, and in particular relates to a device for low-temperature, ventilated sequential preservation of lungs in lung transplantation from a non-heartbeat donor. Background technique [0002] The only effective treatment for end-stage lung disease is lung transplantation. At present, the number of clinical lung transplantation operations has been small and stagnant. The main reason is the shortage of donors. Among them, there is a serious shortage of brain-dead donors (heart heating donors, HBD). Therefore, the majority of scholars focus on non-heartbeat donors. (non heart heating donor, NHBD) research. However, HBD has a beating heart to supply blood, while NHBD donors do the opposite. They have no heart blood supply and have varying degrees of warm ischemic injury. They gradually lose function over time and are not suitable for lung transplantation. The length of warm ischemia injury de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N1/02
Inventor 赵晓刚胥义姜格宁
Owner SHANGHAI PULMONARY HOSPITAL AFFILIATED TO TONGJI UNIV
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