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Device used for preserving lung under low temperature and ventilated situations during non-heart-beating-donor lung transplant

A lung and low temperature technology, applied in the field of auxiliary medical devices, can solve problems such as uneven distribution of lung preservation fluid, increased pulmonary vascular resistance, loss of benefits of endotracheal ventilation, etc., and achieve the effect of resisting NHBD lung heat ischemia injury

Active Publication Date: 2013-12-25
SHANGHAI PULMONARY HOSPITAL AFFILIATED TO TONGJI UNIV +1
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AI Technical Summary

Problems solved by technology

Donor lungs soaked in low-temperature lung preservation fluid maintain a semi-compressed state, which loses the benefits of ventilation, which will lead to an increase in pulmonary vascular resistance and uneven distribution of lung preservation fluid. The classic lung preservation method also has certain disadvantages, losing the benefits of endotracheal ventilation

Method used

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  • Device used for preserving lung under low temperature and ventilated situations during non-heart-beating-donor lung transplant
  • Device used for preserving lung under low temperature and ventilated situations during non-heart-beating-donor lung transplant

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Embodiment Construction

[0015] The invention not only realizes the perfusion and immersion of the donor lung with the low-temperature lung preservation solution, but also sequentially performs intratracheal ventilation, and combines the respective advantages to improve the quality of the NHBD donor lung. The specific use can be divided into three stages, see figure 2 shown.

[0016] First, the donor lung receives low-temperature lung preservation solution perfusion, rapid cooling, and protection of vascular endothelial cells

[0017] The donor’s thoracotomy is performed to take out the heart-lung complex. After taking it out, loosen the elastic opening 4 on the top of the medical elastic rubber bag 1 and put it into the heart-lung complex. The medical elastic rubber bag 1 is provided with a central fixing bracket 7. The central fixing bracket 7 Used to support the donor heart-lung complex, the fixing ring 6 is located at the end of the fixing bracket 7, which can fix the left and right bronchus, so...

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Abstract

The invention belongs to the technical field of auxiliary medical devices, and concretely relates to a device used for preserving a lung under low temperature and ventilated situations during a non-heart-beating-donor (NHBD) lung transplant. The device comprises a medical elastic rubber bag and an outer case, wherein the medical elastic rubber bag is used for placing a complex of the heart and the lung, and is provided with an inlet and an outlet for a low-temperature lung preservation solution, a central fixing support therein and a temperature sensor on an inner wall; the medical elastic rubber bag is arranged in the outer case; mixtures of ice and water are arranged between the outer case and the medical elastic rubber bag and can synergistically maintain the low-temperature state of the medical elastic rubber bag. In addition, two tee pipe joints are provided for respectively connecting the inlet and the outlet of the low-temperature lung preservation solution, left and right ventricular catheters and internal space of the medical elastic rubber bag. The device provided by the invention not only can realize filling and immersing of the low-temperature lung preservation solution, but also can sequentially ventilate in tracheae, thereby combining respective advantages, synergistically confronting warm ischemia injury of NHBD lung, and improving quality of the NHBD lungs.

Description

technical field [0001] The invention belongs to the technical field of auxiliary medical devices, and in particular relates to a device for lung hypothermia and ventilation sequential preservation in non-heartbeat donor lung transplantation. Background technique [0002] The only effective treatment for end-stage lung disease is a lung transplant. At present, the number of clinical lung transplantation operations has increased little and has stagnated. The main reason is the shortage of donors. Among them, there is a severe shortage of brain-dead donors (heart heating donors, HBD). Therefore, most scholars focus on non-heartbeat donors. (non heart heating donor, NHBD) research. However, HBD has a beating heart for blood supply, while NHBD donors, on the contrary, have no heart blood supply, have varying degrees of warm ischemic injury, and gradually lose their function over time, making them unsuitable for lung transplantation. The length of warm ischemia injury determines...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N1/02
Inventor 赵晓刚胥义姜格宁
Owner SHANGHAI PULMONARY HOSPITAL AFFILIATED TO TONGJI UNIV
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