Perhexiline lipidosome injection

A technology of Guanxinning fat and injection, which is applied in the field of medicine to achieve the effects of improving curative effect, improving bioavailability, and increasing retention time
CN103040937BInactive Publication Date: 2015-01-07海南路易丹尼生物科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
海南路易丹尼生物科技有限公司
Publication Date
2015-01-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides perhexiline lipidosome injection which is mainly prepared from salvia miltiorrhiza, ligusticum wallichii, phosphatidyl glycerol, cholesterol, tween 80, edetate disodium and sodium hydrogen sulfite. Compared with the existing preparation, the injection largely improves the stability and the bioavailability of the preparation, smoothly releases drugs, improves the preparation product quality, reduces the poison and side effects, and has more remarkable curative effect.
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Description

technical field

[0001] The invention relates to a novel injection preparation of Guanxinning, in particular to a liposome injection of Guanxinning and a preparation method thereof, belonging to the technical field of medicine. Background technique

[0002] Guanxinning is a traditional Chinese medicine preparation commonly used in recent years for promoting blood circulation and removing blood stasis. Guanxinning injection is composed of two traditional Chinese medicines, Danshen and Chuanxiong. The chemical components in Chuanxiong mainly include alkaloids such as ligustrazine and phenolic substances such as ferulic acid, chrysophanol and ligustrazine. The pharmacological effects of Rhizoma Chuanxiong are mainly through the antagonism of calcium and scavenging free radicals. It has obvious protective and improvement effects on the damage of ischemic tissues and organs. 2 / PGI 2 have antithrombotic effects.

[0003] Salvianolic acid has a protective effect on cerebral isc...

Claims

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