A kind of polypeptide pro-infection agent
A reagent and sequence technology, applied in the fields of peptides, genetic material components, gene therapy, etc., can solve the problem of low infection efficiency of lentiviral vector system
Active Publication Date: 2017-07-21
JILIN UNIV
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Abstract
The invention relates to a polypeptide with HIV infection promoting ability. The HIV infection promoting polypeptide comprises a peptide sequence, containing a terminal C peptide of near extramembrane fragment MPER fragment of an HIV-1 envelope protein GP41. The polypeptide infection promoting agent provided by the invention has significant activity in promoting envelope viral infection, and shows activity superior to that of a common infection promoting agent DEAE at a cellular level. Therefore, the polypeptide infection promoting agent plays an important role in the development of retroviral or lentiviral gene therapy.
Application Domain
Genetic material ingredientsPeptides +1
Technology Topic
PeptideCellular level +7
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PUM


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