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Application of amomum seed or its alcohol extract in the preparation of anti-breast cancer cell proliferation medicine

A technology of breast cancer cells and alcohol extracts, which is applied in the field of traditional Chinese medicine, can solve the problems of inability to obtain curative effect of breast cancer, small side effects of traditional Chinese medicine treatment, and low content of active ingredients.

Inactive Publication Date: 2015-09-23
CAPITAL UNIVERSITY OF MEDICAL SCIENCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The various drugs currently used to treat breast cancer cannot obtain satisfactory curative effects. The side effects of traditional Chinese medicine are small, and can fundamentally regulate the imbalance between various viscera of the human body, which is beneficial to the control of the disease. However, the active ingredients in traditional Chinese medicine The content is relatively small, and the treatment effect is slow, so it is urgent to find a more effective traditional Chinese medicine for the treatment of breast cancer, which will surely bring good news to the majority of breast cancer patients

Method used

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  • Application of amomum seed or its alcohol extract in the preparation of anti-breast cancer cell proliferation medicine
  • Application of amomum seed or its alcohol extract in the preparation of anti-breast cancer cell proliferation medicine
  • Application of amomum seed or its alcohol extract in the preparation of anti-breast cancer cell proliferation medicine

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Embodiment 1

[0024] The preparation of embodiment 1 Amomum extract

[0025] After the amomum was crushed, weighed 1g of the crushed amomum sample, added 40ml of 60% ethanol, crushed at room temperature for 30min, and centrifuged at 4000r / min for 20min to obtain the supernatant extract, dried under reduced pressure at 50°C, dried Weigh the substance after constant weight, and dissolve it with 60% ethanol (as little as possible) to obtain the extract, which is the alcohol extract of Amomum amomum. Sealed and stored at -20°C.

Embodiment 2

[0026] The preparation of embodiment 2 Amomum extract

[0027] After the amomum is crushed, weigh 1g of the crushed amomum sample, add 40ml of 60% ethanol, super-crush at room temperature for 30min, and centrifuge at 4000r / min for 20min to obtain the supernatant extract, and dry it under reduced pressure at 50°C. Alcoholic extract of amomum. Sealed and stored at -20°C.

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Abstract

The invention discloses application of amomum fruit or alcohol extract thereof to preparation of a medicine for resisting proliferation of breast cancer cells. Comparative study shows that breast cancer cells are extremely sensitive to amomum fruit, and amomum fruit has anticancer activity even superior to that of resveratrol, so as to provide a strong basis for the clinical application of amomum fruit, especially application to treatment aiming at breast cancer. Therefore, the invention has vital significance.

Description

technical field [0001] The invention relates to a traditional Chinese medicine and its application in the preparation of anti-tumor cell proliferation medicine. It particularly relates to the application of a traditional Chinese medicine in the preparation of anti-proliferation drugs for breast cancer cells, and the traditional Chinese medicine is amomum or its extract. The invention belongs to the field of traditional Chinese medicine. Background technique [0002] Epidemiological studies in recent years have shown that breast cancer has become one of the most common malignant tumors in women, and its morbidity and mortality are increasing year by year. Studies have found that under the influence of carcinogenic factors, breast ductal epithelial cells undergo abnormal proliferation, and eventually develop into tumors beyond the limit of self-repair. The current treatment is mainly based on surgical resection, supplemented by chemotherapy, endocrine therapy and radiotherap...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61P35/00
Inventor 赵光李珺杨捷
Owner CAPITAL UNIVERSITY OF MEDICAL SCIENCES
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