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Externally applied traditional Chinese medicine composition for treating dysmenorrhea, as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of external Chinese medicine composition for treating dysmenorrhea and its preparation method and application, and the field of external Chinese medicine composition for treating dysmenorrhea, can solve problems such as unsatisfactory curative effect, backward technology and dosage form, skin irritation, etc. Achieve the effect of improving comprehensive effect, no allergic reaction, and inhibiting swelling

Inactive Publication Date: 2013-06-26
南京海思创新生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some of them will cause skin irritation, the technology and dosage form are relatively backward, and the curative effect is not ideal

Method used

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  • Externally applied traditional Chinese medicine composition for treating dysmenorrhea, as well as preparation method and application thereof
  • Externally applied traditional Chinese medicine composition for treating dysmenorrhea, as well as preparation method and application thereof
  • Externally applied traditional Chinese medicine composition for treating dysmenorrhea, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0140] Embodiment 1, the external use Chinese medicine composition of treating dysmenorrhea. The composition by weight of each component is: Rhizoma Cyperi 65.6g, Artemisia argyi 65.6g, Angelica 32.8g, Angelica dahurica 32.8g, Magnolia officinalis 16.4g, Motherwort 32.8g, Agarwood 8.6g, Turmeric 47.7g. The preparation steps are as follows: ⑴. Mix the whole amount of Agarwood with Cyperi cyperi, Artemisia argyi, Angelica, Angelica, Magnolia officinalis, Motherwort, and Turmeric, and mix them evenly; ⑵. Add 0.5% Span-80, grind them into fine powder by grinding and mixing machine powder, that is, powder within 200 meshes; (3) add 5 times the amount of ethanol to the remaining half amount of motherwort, and extract twice with 60% ethanol under reflux, each time for 2 hours; combine the extracts, filter, and use the dregs for later use; (4) recover ethanol from the filtrate Continue to concentrate until the volume is about 1:0.6‐0.7; ⑸. Half of Cyperus cyperi, Artemisia argyi, Ange...

Embodiment 2

[0142] Embodiment 2, the external Chinese medicine composition of treatment dysmenorrhea. The weight ratio composition of each component is: Rhizoma Cyperi 65.6g, Artemisia argyi 65.6g, Angelica 32.8g, Angelica dahurica 32.8g, Magnolia officinalis 16.4g, Motherwort 32.8g, Agarwood 8.6g, Asarum 3.1g, Paeoniae Alba 16.4g, Peony Skin 16.4g, Chuanxiong 32.8g, Turmeric 47.7g, Corydalis 26.2g, Clove 3.1g, Saffron 0.8g. The preparation steps are as follows: ⑴. The whole amount of agarwood, asarum, clove, and saffron, and half of each amount of Cyperus cyperi, wormwood, angelica, angelica, magnolia officinalis, motherwort, white peony root, peony bark, chuanxiong, turmeric, and corydalis, and mix evenly; ⑵. Add 0.5% Tween‐80, pulverize it by grinding and mixing machine, and pulverize it into a very fine powder, which is a medicinal powder within 200 meshes; (3) The remaining half of motherwort, white peony root, and Corydalis three flavors, 7 times the amount of ethanol, 50% ethanol r...

Embodiment 3

[0143] Embodiment 3, the external use Chinese medicine composition of treating dysmenorrhea. The composition by weight of each component is: Rhizoma Cyperi 65.6g, Artemisia argyi 65.6g, Angelica 32.8g, Angelica dahurica 32.8g, Magnolia officinalis 16.4g, Motherwort 32.8g, Agarwood 8.6g, Turmeric 47.7g. The preparation steps are as follows: ⑴. Mix the whole amount of Agarwood with Cyperi cyperi, Artemisia argyi, Angelica, Angelica, Magnolia officinalis, Motherwort, and Turmeric, and mix them evenly; ⑵. Add 0.5% Span-80, grind them into fine powder by grinding and mixing machine powder, that is, powder within 200 meshes; (3) add 7 times the amount of ethanol to the remaining half amount of motherwort, and extract twice with 50% ethanol under reflux, each time for 1.5 hours; combine the extracts, filter, and use the dregs for later use; (4) recover ethanol from the filtrate Continue to concentrate until the volume is about 1:0.6‐0.7; ⑸. Half of Cyperus cyperi, Artemisia argyi, An...

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Abstract

The invention relates to an externally applied traditional Chinese medicine composition for treating dysmenorrhea, as well as a preparation method and an application thereof. The externally applied traditional Chinese medicine composition comprises the following active pharmaceutical ingredients in parts by weight: 5-10 parts of nutgrass galingale rhizome, 5-10 parts of argy wormwood leaf, 3-5 parts of Chinese angelica, 3-5 parts of dahurian angelica root, 1-4 parts of officinal magnolia bark, 3-5 parts of motherwort herb, 0.5-2 parts of Chinese eaglewood and 3-6 parts of turmeric. The optimized scheme is as follows: one or more of 1-4 parts of white paeony root, 3-5 parts of Szechuan lovage rhizome, 2-5 parts of rhizoma corydalis, 1-4 parts of tree peony bark, 0.1-0.6 part of manchurian wildginger, 0.05-0.2 part of saffron and 0.2-0.8 part of flos caryophyllata are added. The externally applied traditional Chinese medicine composition disclosed by the invention can improve the comprehensive effects for treating the dysmenorrhea and simultaneously play the roles in inhibiting the contraction of uterine smooth muscle, strongly reliving the spasm of the uterine smooth muscle, alleviating pain, inhibiting swelling, promoting blood circulation, removing blood stasis, dilating blood capillaries and the like. Simultaneously, the externally applied traditional Chinese medicine composition disclosed by the invention has smaller toxicity and side effects and can not cause allergic reactions. The invention further provides the preparation method of the medicament and the application thereof in preparation of externally applied medicaments for treating the dysmenorrhea.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to an external Chinese medicinal composition for treating dysmenorrhea. The present invention also relates to the external Chinese medicine composition for treating dysmenorrhea, its preparation method and application. Background technique [0002] Dysmenorrhea refers to women's lower abdomen or waist pain or pain reaching the waist and bones before and after menstruation or during menstruation, and it occurs every time with the menstrual cycle, also known as abdominal pain during menstruation. Dysmenorrhea is a common and frequently-occurring disease in gynecology. Traditional Chinese medicine believes that dysmenorrhea is a disease caused by various factors. Emotional discomfort, depression and anger hurt the liver, and worry hurts the spleen, all of which can cause adverse qi movement, stagnation of qi and blood stasis, blood stagnation, pain in the uterus, voxel kid...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/70A61K9/06A61P15/00
Inventor 储益平管伦兴朱华荣
Owner 南京海思创新生物科技有限公司
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