Medicine for treating ischemic cerebral apoplexy and preparation method thereof

A technology for ischemic stroke and drugs, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., and can solve problems such as treating the symptoms but not the root cause, large side effects, and drug resistance

Inactive Publication Date: 2013-07-03
LUOYANG LUOTONG HOSPITAL +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Western medicine treatment is characterized by symptomatic treatment, which treats the symptoms but not the root cause, easy to relapse, long-term use has drug resistance, and has many side effects

Method used

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  • Medicine for treating ischemic cerebral apoplexy and preparation method thereof
  • Medicine for treating ischemic cerebral apoplexy and preparation method thereof
  • Medicine for treating ischemic cerebral apoplexy and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] The medicine of the present embodiment for the treatment of wind-phlegm congestion, blockage and choroidal ischemic stroke (cerebral thrombosis, cerebral infarction) is made of the following components in parts by weight:

[0127] Danshen 6.2, Chishao 5.8, Chuanxiong 6.2, Safflower 5.8, Gentiana 6.2, Astragalus 7.8, Guizhi 5.0, Pueraria 5.8, Codonopsis 6.2, Cyperus 3.4, Corydalis 3.8, Wuyao 4.6, Achyranthes bidentata 6.2, Centipede 0.8, Turtle Insect 4.2, cicada slough 3.8, earthworm 6.2, Eucommia 5.8, whole insect 0.4, Shenjincao 5.8.

Embodiment 2

[0129] The medicine of the present embodiment for the treatment of wind-phlegm congestion, blockage and choroidal ischemic stroke (cerebral thrombosis, cerebral infarction) is made of the following components in parts by weight:

[0130]Danshen 5.8, Chishao 6.2, Chuanxiong 5.8, Safflower 6.2, Gentiana 5.8, Astragalus 8.2, Guizhi 4.6, Pueraria 6.2, Codonopsis 5.8, Cyperus 3.8, Corydalis 3.4, Wuyao 5.0, Achyranthes bidentata 5.8, Centipede 0.8, Turtle Insect 3.8, cicada slough 4.2, earthworm 5.8, eucommia 6.2, whole insect 0.4, slender grass 6.2.

Embodiment 3

[0132] The medicine of the present embodiment for the treatment of wind-phlegm congestion, blockage and choroidal ischemic stroke (cerebral thrombosis, cerebral infarction) is made of the following components in parts by weight:

[0133] Danshen 6.0, Chishao 6.0, Chuanxiong 6.0, Safflower 6.0, Gentiana 6.0, Astragalus 8.0, Guizhi 4.8, Pueraria 6.0, Codonopsis 6.0, Cyperus 3.6, Corydalis 3.6, Wuyao 4.8, Achyranthes bidentata 6.0, Centipede 0.8, Turtle Insect 4.0, Cicada slough 4.0, Dilong 6.0, Eucommia 6.0, All insects 0.4, Shenjincao 6.0.

[0134] The medicine of above-mentioned embodiment 1-3, combine figure 1 , taking the mixture as an example:

[0135] First, dry the components of each weight part, make coarse powder 250-850um or 24-65 mesh, and mix; put the powder into an ultrasonic extractor, add 5-7 times the total weight of each component Soak in 70% ethanol for 30-60 minutes, continue to add 70% ethanol to 8-10 times the amount, extract at 45-55°C for 1.0-1.5 hours, ...

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Abstract

The invention discloses a medicine for treating ischemic cerebral apoplexy. The medicine is prepared from the following ingredients by weight: 5.4-6.6 parts of salvia miltiorrhiza, 5.4-6.6 parts of radix paeoniae rubra, 5.4-6.6 parts of rhizoma ligustici wallichii, 5.4-6.6 parts of safflower, 5.4-6.6 parts of radix gentianae macrophyllae, 7.2-8.8 parts of astragalus mongholicus, 4.2-5.4 parts of cassia twig, 5.4-6.6 parts of kudzuvine root, 5.4-6.6 parts of codonopsis, 3.0-4.2 parts of nutgrass galingale rhizome, 3.0-4.2 parts of rhizoma corydalis, 4.2-5.4 parts of the root of three-nerved spicebush, 5.4-6.6 parts of radix cyathulae, radix linderae, 0.6-1.0 parts of centipede, 3.2-4.8 parts of ground beetle, 3.2-4.8 parts of lumbricus cicada, 5.4-6.6 parts of earthworm, 5.4-6.6 parts of the bark of eucommia, 0.3-0.5 parts of scorpion, and 5.4-6.6 parts of common club moss herb. The medicine is simple and reasonable in composition, and has the functions of promoting blood circulation to remove blood stasis, removing wind and dredging collaterals and relieving spasmolysis and pain. The invention further discloses a preparation method of the medicine, which comprises the following steps: drying, crushing and mixing each ingredient based on the weight part, placing the mixed powder into a supersonic extractor, adding 70% ethanol to extract effective components so as to obtain the alcohol extract of the effective components, placing the extract still for 48-72h to obtain alcohol precipitation supernatant, filtering the supernatant, and recycling ethanol to obtain the concentrated extract of the effective components. The supersonic extraction has the special advantages of low extraction temperature, high extraction rate and short extraction time.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and mainly relates to a medicine for treating ischemic cerebral apoplexy and a preparation method thereof. Background technique [0002] Cerebrovascular disease, also known as cerebrovascular accident, cerebral apoplexy or cerebral apoplexy, is a group of diseases characterized by loss of local neurological function caused by cerebral blood circulation disorder; including intracranial and extracranial artery, vein and venous sinus diseases ; Mainly arterial disease, more common in middle-aged and elderly people. Hypertension, blood viscosity, smoking, abnormal metabolism of vascular wall smooth muscle cells and other reasons are the main pathogenic factors of this disease. According to the pathogenesis of cerebral apoplexy, it can be divided into three stages, namely, the acute stage, the recovery stage and the sequelae stage. More than 95% of the stroke patient...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P9/10A61K35/64A61K35/62A61K35/646A61K35/648
Inventor 李勇王进
Owner LUOYANG LUOTONG HOSPITAL
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