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Traditional Chinese medicine composition and preparation method thereof

A technology of composition and natural medicine, applied in the direction of drug combination, pharmaceutical formulation, anti-tumor drug, etc., can solve the problems of malnutrition, dehydration of patients, acid-base balance disorder, etc., and achieve obvious synergy, enhanced inhibitory effect, and increased inhibitory effect. effect of action

Inactive Publication Date: 2013-07-17
阚兆云
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AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine composition and preparation method thereof
  • Traditional Chinese medicine composition and preparation method thereof

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Experimental program
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Embodiment approach

[0034] The first step: preparation of various extracts

[0035] (1) Preparation of Artemisia argyi and Baimu Perfume Concentrated Extract

[0036] According to the compatibility ratio of 1:1 or 1-4:1 other ratios, take mugwort leaves and white wood, soak in 10 times the amount of distilled water, soak for 1 hour, heat and decoct on the electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate and medicinal residue Add 6 times more distilled water, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brown-yellow powder.

[0037] (2) Preparation of Artemisia argyi ethyl acetate extract

[0038] Appropriate amount of Artemisia argyi leaves is extracted with 95% ethanol, and the solvent is recovered to obtain an alcohol extraction extract. The extract is extracted with n-h...

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Abstract

The invention relates to a natural medicine composition and a preparation method thereof, as well as application of the composition in preparing attenuation synergism medicines for preparing cancer chemotherapy. The natural medicine composition is prepared from a moxa leaf aquilaria sinensis decocted concentrated extract, a moxa leaf ethyl acetate extract, an aquilaria sinensis chloroform extract and an aquilaria sinensis hexane extract according to a proportion of (2-7): (2-5): (3-8): (2-5). The composition has a good curative effect on cancer chemotherapy related diarrhoea and can also play a synergistic role in the cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of Artemisia argyi and Baimu Perfume decoction concentrated extract, Artemisia argyi ethyl acetate extract, Akira chloroform extract and Akira hexane extract , the preparation method of the natural medicine composition and the use of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemothera...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/285A61P1/12A61P35/00A61K36/282
Inventor 阚兆云
Owner 阚兆云
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