Traditional Chinese medicine composition with hypoglycemic effect, its application and preparation method

A composition and blood sugar-lowering technology, which is applied in the direction of drug combination, medical preparations containing active ingredients, sugar-coated pills, etc., can solve the problems of complex production process, difficult synthesis, large side effects, etc., and achieve simple production process and wide range of drug sources , less toxic and side effects

Active Publication Date: 2017-10-13
金士力佳友(天津)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs can control and delay diabetes to a certain extent, the disadvantages of complex production process, high price, difficult synthesis, and large side effects are difficult to overcome.
Moreover, Western medicines are resistant, and patients must constantly change medicines

Method used

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  • Traditional Chinese medicine composition with hypoglycemic effect, its application and preparation method
  • Traditional Chinese medicine composition with hypoglycemic effect, its application and preparation method
  • Traditional Chinese medicine composition with hypoglycemic effect, its application and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The prescription of Chinese medicine composition is as shown in the table below:

[0027]

[0028]

[0029] Crumble jujube kernels and aloe vera, mix them with American ginseng, Kudingcha, hawthorn and Anemarrhena decoction pieces, add 8 times the amount of 70% ethanol to slightly boil and reflux for extraction twice, each time for 1 hour, filter the extract, and concentrate the filtrate under reduced pressure (50°C -70°C) to a specific gravity of 1.0-1.25 (50°C); add 10 times the weight of the raw material to the filter residue and extract by microboiling and reflux twice, each time for 1 hour, filter the extract, and concentrate the filtrate under reduced pressure (50°C-70°C ) to a specific gravity of 1.04-1.06 (50°C), let it cool, add ethanol to make the alcohol content reach 50%, let it stand for 24-48 hours, take the alcohol precipitation supernatant and filter, and concentrate the filtrate under reduced pressure (50°C-70°C) to a specific gravity of 1.0-1.25 ...

Embodiment 2

[0032] The prescription of Chinese medicine composition is as shown in the table below:

[0033]

[0034] Crumble jujube kernels and aloe vera, mix them with American ginseng, Kudingcha, hawthorn and Anemarrhena decoction pieces, add 6 times the amount of 65% ethanol to reflux at 80°C for 3 times, each time for 0.5 hours, filter the extract, and reduce the filtrate at 40-50°C When concentrated under pressure to 50°C, the specific gravity is 1.1-1.2; add 8 times the weight of the raw material to the filter residue, reflux extraction at 90°C for 3 times, each time for 0.5 hours, filter the extract, and concentrate the filtrate to 50°C under reduced pressure at 50°C-70°C The specific gravity is 1.0-1.09, let it cool, add ethanol to make the alcohol content reach 40%, let it stand for 12-24 hours, take the alcohol precipitation supernatant and filter, the filtrate is concentrated under reduced pressure at 40-50°C to 50°C, and the specific gravity is 1.0-1.2 ; Alcohol extraction...

Embodiment 3

[0037] Kudingcha 382.5g, hawthorn 382.5g, jujube seed 382.5g, Anemarrhena 510g, aloe 85g, American ginseng 127.5g, add water 1000ml, soak for 30 minutes, fry on medium heat for 1 hour, pour out the supernatant, add water 800ml, medium Cook on high heat for 40 minutes, pour out the supernatant. Combine the two supernatants and serve.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition with hypoglycemic effect. 700-1300 servings of aloe vera and 1050-1950 servings of American ginseng. The traditional Chinese medicine composition of the invention has the effects of clearing heat and producing body fluid, eliminating accumulation and resolving phlegm, and replenishing qi and nourishing yin. The invention also provides the application of the traditional Chinese medicine composition and the preparation method of the extract. In addition, a specific extract of the traditional Chinese medicine composition, a specific dosage form and its usage and dosage are disclosed.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition with hypoglycemic effect, its application, its extract and a preparation method of some dosage forms. Background technique [0002] Diabetes mellitus is a chronic, metabolic disease characterized by chronic hyperglycemia and concurrent microvascular and macrovascular lesions caused by abnormal insulin secretion and action defects caused by multiple factors such as genetics, environment, and diet. At present, there is no effective drug or means to cure it, only to control blood sugar to a certain range so as to reduce and delay the occurrence of complications. At present, the drugs for hypoglycemia are mainly western medicines, including sulfonylureas (SUs), biguanides (BGs) and α-glucosidase inhibitors (α-GIs), thiazolidinediones ( TZD) and fast-acting insulin secretion-stimulating drugs. Although these drugs can control an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8964A61K9/28A61P3/10
Inventor 闫希军朱永宏李长文仝小林徐咏全崔瀚元凌芳
Owner 金士力佳友(天津)有限公司
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