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Cooling blood callus prescription extractive and compounded resveratrol cooling blood callus oil preparation for treating skin burn

A technology of resveratrol and extract, applied in the field of medicine, can solve the problems of poor moisturizing and slow-release effect, low biocompatibility, low bioavailability, etc., so as to reduce nursing workload, shorten treatment time, beneficial to repair

Active Publication Date: 2014-11-12
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the pharmaceutical preparations used to treat burns are mostly water, ointment (or oil extract), powder, spray, cream, etc., which have low bioavailability, poor sensory properties, and low biocompatibility , poor moisturizing and sustained release effect, inconvenient to use, etc.

Method used

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  • Cooling blood callus prescription extractive and compounded resveratrol cooling blood callus oil preparation for treating skin burn
  • Cooling blood callus prescription extractive and compounded resveratrol cooling blood callus oil preparation for treating skin burn
  • Cooling blood callus prescription extractive and compounded resveratrol cooling blood callus oil preparation for treating skin burn

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Weigh 40g Coptis chinensis, 40g Cortex Phellodendri, 40g Huangling, 30g rhubarb, 30g Sophora flavescens, 30g white fresh skin, 20g cicada, 10g octopus, 60g comfrey, 30g Burnet, 20g safflower, 15 earthworms, 6 grams of borneol, mixed and pulverized medicinal materials except borneol, passed through 10 mesh molecular mesh, added 3000ml of 60% ethanol, refluxed and extracted in a round bottom flask at 80-85°C for 3h. Then filter the mixture of medicinal material powder and ethanol to obtain filter residue 1 and filtrate 1. Take the filter residue 1 and add 3000ml of 60% ethanol to a round bottom flask for reflux extraction at 80-85°C for 2h. Then filter the mixture of filter residue and ethanol to obtain filter residue 2 and filtrate 2. Take the filter residue 2 and add 3000ml of 60% ethanol to a round bottom flask for reflux extraction at 80-85°C for 1h. Then filter the mixture of filter residue and ethanol to obtain filter residue 3 and filtrate 3 .

[0044] Take the ...

Embodiment 2

[0046] Weigh 30g Coptis chinensis, 50g Phellodendron Phellodendri, 30g Huangling, 40g rhubarb, 40g Sophora flavescens, 40g white fresh skin, 25g cicada, 15g sea octopus, 80g comfrey, 40g Burnet, 30g safflower, 20 earthworms, 10 grams of borneol, mix and pulverize the medicinal materials except borneol, pass through 10 mesh molecular mesh, add 4000ml of 80% ethanol, reflux and extract in a round bottom flask at 80-85°C for 3h. Then filter the mixture of medicinal material powder and ethanol to obtain filter residue 1 and filtrate 1. Take the filter residue 1 and add 4000ml of 80% ethanol to a round bottom flask for reflux extraction at 80-85°C for 2h. Then filter the mixture of filter residue and ethanol to obtain filter residue 2 and filtrate 2. Take the filter residue 2 and add 4000ml of 80% ethanol to a round bottom flask for reflux extraction at 80-85°C for 1h. Then filter the mixture of filter residue and ethanol to obtain filter residue 3 and filtrate 3 .

[0047] Take...

Embodiment 3

[0049] Weigh 30g Coptis chinensis, 30g Cortex Phellodendri, 30g Huangling, 20g rhubarb, 20g Sophora flavescens, 20g white fresh skin, 15g cicada, 5g sea octopus, 40g comfrey, 20g Burnet, 10g safflower, 10 earthworms, 5 grams of borneol, mixed and crushed medicinal materials except borneol, passed through 10 mesh molecular mesh, added 2000ml of 40% ethanol, and refluxed in a round bottom flask at 80-85°C for 3h. Then filter the mixture of medicinal material powder and ethanol to obtain filter residue 1 and filtrate 1. Take the filter residue 1 and add 2000ml of 40% ethanol to a round bottom flask for reflux extraction at 80-85°C for 2h. Then filter the mixture of filter residue and ethanol to obtain filter residue 2 and filtrate 2. Take the filter residue 2 and add 2000ml of 40% ethanol to a round bottom flask for reflux extraction at 80-85°C for 1h. Then filter the mixture of filter residue and ethanol to obtain filter residue 3 and filtrate 3 .

[0050] Take the filter res...

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Abstract

The invention relates to the field of medicines, and in particular relates to a cooling blood callus prescription extractive and a compounded resveratrol cooling blood callus oil preparation for treating skin burn. The callus prescription extractive comprises the following raw materials by weight: 30-50g of goldthread, 30-50g of golden cypress, 30-50g of radix scutellariae, 20-40g of rheum officinale, 20-40g of radix sophorae flavescentis, 20-40g of the root bark of shaggy-fruited dittany, 10-30g of periostracum cicada, 5-15g of cuttlebone, 50-80g of lithospermum, 20-40g of garden burnet, 10-30g of red flower and 10-20g of earthworm. The compounded resveratrol cooling blood callus oil preparation is prepared by combining the callus prescription extractive and resveratrol. The preparation has the anti-inflammatory and debridement effects, can not only cover the wound surface, reduce infection, but also can actively participate in the burn wound healing, thus greatly improving the treating effect of wound surfaces of burn, trauma and the like.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an extract of Liangxueyushang recipe and compound resveratrol Liangxueyoushang oil preparation for treating skin burns. Background technique [0002] Skin burn is a common clinical disease, often accompanied by complications, which often brings great pain and inconvenience to the patient, affects the external appearance of the patient, and can threaten the life of the patient in severe cases. Therefore, actively promoting wound repair is of great significance to save patients' lives, reduce complications, relieve patients' pain, prevent scar formation, and improve treatment effects. At present, many drugs and preparations for the treatment of skin burns have been developed at home and abroad. Some drugs have very accurate effects, which provide a good idea and basis for clinical development of new drugs and preparations. With the development of bionics and chemical synthesis te...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61K9/00A61P17/02A61K35/56A61K35/64A61K35/618A61K35/62
Inventor 张黎郑敏李国营严莉
Owner GUANGDONG PHARMA UNIV
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