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Application of PES (polyether sulfone) microporous membrane in automatic liquid stopper

A technology of microporous film and polyethersulfone, which is applied in the direction of subcutaneous injection devices, etc., can solve the problems of low BP value, slow flow rate, poor hydrophilicity of liquid stop membrane, etc., and achieve safe and convenient infusion process, increase safety and convenience effect

Inactive Publication Date: 2013-12-25
杭州费尔过滤技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, ordinary liquid-stopping membranes have problems such as poor hydrophilicity, slow flow rate, and too low BP value, which lead to certain limitations in the use of membrane-structured automatic liquid-stopping infusion sets.

Method used

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  • Application of PES (polyether sulfone) microporous membrane in automatic liquid stopper

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Dissolve polyethersulfone accounting for 10 (wt)% of the total mass in N,N-dimethylacetamide, and add polyvinylpyrrolidone accounting for 8 (wt)% of the total mass, and stir at a temperature of 25°C It is dissolved, passed through a 200-mesh filter, and vacuum degassed to obtain a casting solution. At a temperature of 25°C, the casting solution was scraped on a non-woven fabric to form a 0.2 mm thick liquid film, and left to evaporate in air with a relative humidity of 40% for 30 seconds to initially gel. At a temperature of 40°C, phase inversion is carried out in a gel water bath containing 5 (wt)% of the total mass of N,N-dimethylacetamide to obtain a polyethersulfone microporous membrane.

Embodiment 2

[0027] Dissolve polyethersulfone accounting for 15 (wt)% of the total mass in N,N-dimethylacetamide, and add polyvinylpyrrolidone accounting for 10 (wt)% of the total mass, and stir at a temperature of 50°C It is dissolved, passed through a 200-mesh filter, and vacuum degassed to obtain a casting solution. At a temperature of 40°C, the casting solution was scraped on a non-woven fabric to form a 0.2mm thick liquid film, and left to evaporate in air with a relative humidity of 80% for 120s to initially gel. At a temperature of 40°C, phase inversion is carried out in a gel water bath containing 5 (wt)% of the total mass of N,N-dimethylacetamide to obtain a polyethersulfone microporous membrane.

Embodiment 3

[0029] Dissolve polyethersulfone accounting for 15 (wt)% of the total mass in N,N-dimethylacetamide, and add polyvinylpyrrolidone accounting for 8 (wt)% of the total mass, and stir at a temperature of 40°C It is dissolved, passed through a 200-mesh filter, and vacuum degassed to obtain a casting solution. At a temperature of 20°C, the casting solution was scraped on a non-woven fabric to form a 0.3 mm thick liquid film, and left to evaporate in air with a relative humidity of 60% for 80 seconds to initially gel. At a temperature of 25°C, phase inversion is carried out in a gel water bath containing 5 (wt)% of the total mass of N,N-dimethylacetamide to obtain a polyethersulfone microporous membrane.

[0030] The polyethersulfone microporous film prepared in Examples 1-3 is cut into a certain shape and then installed in the automatic stop liquid device of the infusion set through ultrasonic welding and other processes, all of which can achieve a good automatic stop liquid functi...

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Abstract

The invention discloses an application of a PES (polyether sulfone) microporous membrane, and specifically is an application of the PES microporous membrane in an automatic liquid stopper. The PES microporous membrane is utilized as an automatic liquid stopping membrane of an infusion apparatus, wherein the average aperture of the PES microporous membrane is 1-20 microns and the thickness of the PES microporous membrane is 10-400 microns. The application of the PES microporous membrane in the automatic liquid stopper has the advantages that the safety andthe convenience in the use of an automatic liquid stopping infusion apparatus are largely improved; asymmetrical PES microporous membrane with high hydrophilicity can effectively exert the function of the liquid stopping membrane, does not influence the flow of liquid medicine in the infusion apparatus in an infusion process and can immediately stop the liquid medicine after the infusion process is finished, so that air is prevented from entering the vein, and the whole infusion process is safer and more convenient.

Description

technical field [0001] The invention relates to the application of a polyethersulfone microporous membrane, in particular to the application of a polyethersulfone microporous membrane in an automatic liquid stopper. Background technique [0002] With the rapid development of the disposable medical device industry, the manufacturing threshold of ordinary products is gradually lowered, and the demands of medical personnel for the humanized functions of medical devices continue to increase. Medical device companies need an innovative product to break through the dilemma of homogeneous competition. [0003] Automatic stop liquid infusion set (Airstop, also known as self-drip stop, self-sealing, anti-drainage infusion set), is a new type of disposable medical consumables that replace ordinary infusion sets. The liquid level does not drop for a long time at the designated position, automatically preventing air from entering the vein, thereby reducing the work pressure of the nursi...

Claims

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Application Information

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IPC IPC(8): A61M5/38
Inventor 虞佳黛贾建东陈昕朱赞青
Owner 杭州费尔过滤技术有限公司
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