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Traditional Chinese medicine for treating body-resistance-weak and pathogen-strong type chronic osteomyelitis and preparation method thereof

A technology for chronic osteomyelitis, positive deficiency and evil prosperous, applied in pharmaceutical formulations, medical preparations containing active ingredients, bone diseases, etc., can solve the problems of decreased efficacy, easy recurrence, drug resistance variation, etc., and achieves less toxic and side effects. , the effect of exact curative effect

Inactive Publication Date: 2014-01-22
姜永杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the irrational use of antibiotics, pathogenic bacteria often have drug resistance and mutation, which reduces the curative effect
Although surgical treatment can remove the lesion, it has the disadvantage of easy recurrence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0065] The present invention also provides a method for preparing the above-mentioned traditional Chinese medicine. The dosage form of the traditional Chinese medicine for oral administration is a tablet, and the preparation method includes the following steps:

[0066] The first step: the raw materials of the traditional Chinese medicine are mixed in proportions, and ethanol with an alcohol concentration of 80-90% relative to the mass of the mixture is added 3 to 5 times, heated to reflux for 1 to 2 hours, extracted, and filtered to obtain the first extract The dregs obtained by filtration are then added with ethanol with an alcohol concentration of 80-90% relative to the mass of the dregs 1 to 3 times, heated to reflux for 35 to 45 minutes, extracted, filtered to obtain a second extract, and the first extract is combined with The second extracts were combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0067] The second s...

Embodiment 1

[0083] Example 1: Tablet

[0084] Take 340g of Achyranthes bidentata, 180g of Acanthopanax senticosus, 160g of Thousand-Needle Grass, 230g of Egg Ginseng, 310g of Bloodwind Vine, 120g of Stone Flower, 110g of Ceratophyllum, 230g of Sargentodoxa vulgaris, 160g of Strawberry, 110g of Evening Primrose, Lantana camara 120g flowers, 240g elderberry and 110g powdery 薆薢;

[0085] Prepare according to the following steps:

[0086] The first step: mixing the raw materials of the traditional Chinese medicine, adding ethanol with an alcohol concentration of 90% relative to the mass of the mixture, heating and refluxing for 2 hours, extracting, filtering to obtain the first extract, and adding the filtered dregs The ethanol with an alcohol concentration of 90%, which is twice the mass of the drug residue, is heated and refluxed for 45 minutes, extracted and filtered to obtain the second extract, the first extract and the second extract are combined, concentrated under reduced pressure to remove...

Embodiment 2

[0089] Example 2: Capsules

[0090] Take Achyranthes bidentata 310g, Acanthopanax 160g, Thousand-Needle Grass 190g, Egg Ginseng 220g, Bloodwind Vine 340g, Stone Flower 140g, Ceratophyllum 130g, Sargentodoxa 210g, Strawberry 170g, Evening Primrose 130g, Lantana camara 140g flowers, 220g elderberry and 130g powdered vinegar;

[0091] Prepare according to the following steps:

[0092] In the first step, the raw materials of the traditional Chinese medicine are mixed, and ethanol with an alcohol concentration of 90%, which is 4 times the mass of the mixture, is added, heated to reflux for 60 minutes, extracted and filtered to obtain the first extract; the dregs obtained by filtration are added again Ethanol with an alcohol concentration of 90%, which is 3 times the mass of the drug residue, is heated and refluxed for 30 minutes, extracted and filtered to obtain a second extract; the first extract and the second extract are combined, concentrated under reduced pressure to remove the etha...

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Abstract

The invention provides a traditional Chinese medicine for treating body-resistance-weak and pathogen-strong type chronic osteomyelitis, and a preparation method thereof. The traditional Chinese medicine comprises a medicine for oral administration and a medicine for external use, wherein the medicine for oral administration comprises the following medicinal materials: radix achyranthis bidentatae, radix acanthopanacis semticosi, stellaria yunnanensis, codonopsis convolvulacea, ventilago leiocarpa benth, corallodiscus flabellatus, pyrola, sargentgloryvine stem, lovage, evening primrose, rhododendron delavayi, elderberry and rhizoma dioscoreae hypoglaucae; the medicine for external use comprises the following medicinal materials: pararuellia delavayana, cupparis spinosa, common andrographis herb, helwingia root, radix rubiae, siberian walking fern, paniculate spotflower herb, cryptolepis buchananii, fir club moss, radermachera sinica and cortex kadsurae radicis. The traditional Chinese medicine provided by the invention has the effects of combining oral administration and external use, strengthening the body resistance, eliminating pathogen, benefiting qi, nourishing blood, removing toxicity, promoting granulation, activating blood, dissolving stasis and relieving swelling and pains, has an extract curative effect for the body-resistance-weak and pathogen-strong type chronic osteomyelitis, and has slight toxic and side effects.

Description

Technical field [0001] The invention relates to medical preparations containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for the treatment of chronic osteomyelitis of the type of positive deficiency and evil and its preparation method. Background technique [0002] Most chronic osteomyelitis develops as a result of improper or untimely treatment of acute osteomyelitis. However, if the pathogenic bacteria of acute osteomyelitis is low in virulence or the patient's resistance is strong, it may be subacute or chronic osteomyelitis from the beginning. Osteomyelitis caused by skin wound infection is often chronic osteomyelitis from the beginning. . The pathogenic bacteria of chronic osteomyelitis is also mainly Staphylococcus aureus. Patients with chronic sinus tracts often have mixed infections of multiple bacteria. This disease is common in children with long tube bone metaphysis. Most have a history of acute osteomyeli...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K36/74A61P19/00A61P7/00
Inventor 姜永杰李霞牛霞崔新燕王霞姜永梅陈强姜永华薛晓媛
Owner 姜永杰
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