Method for constructing nanoparticle-nanorod composite structure and constructed composite structure

A nanoparticle and composite structure technology, applied in the field of constructing composite structures of nanoparticles and nanorods, can solve problems such as research on optical characteristics of plasmonic elements

Inactive Publication Date: 2014-01-29
SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the combined structure between nanorods and nanoparticles is still difficult to obtain by previous methods. Therefore, there are relatively few studies on the optical characteristics of plasmonic elements in the one-dimensional combined structure containing nanorods and nanoparticles.

Method used

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  • Method for constructing nanoparticle-nanorod composite structure and constructed composite structure
  • Method for constructing nanoparticle-nanorod composite structure and constructed composite structure
  • Method for constructing nanoparticle-nanorod composite structure and constructed composite structure

Examples

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Effect test

Embodiment 1

[0053] 1. Construction of a 60nm×90nm two-dimensional DNA substrate connected with a single-stranded DNA probe

[0054] The sequences listed in Table 2 were used to replace the corresponding sequences in Table 1 to construct a 60 nm×90 nm two-dimensional DNA substrate connected with a single-stranded DNA probe. Specifically, use the serial numbers in Table 2 as Ball-4, Ball-6, Ball-128, Rod-215, Rod-201, Rod-200, Rod-177, Rod-176, Rod-152 and Rod-153 The sequence numbers in Table 1 are 4, 6, 128, 215, 201, 200, 177, 176, 152, and 153, respectively, based on the same method as the above-mentioned method for constructing a 60nm×90nm substrate to construct a single-stranded DNA 60nm x 90nm two-dimensional DNA substrate for probes. Therefore, on the constructed two-dimensional DNA substrate, there are connected single-stranded DNA probes protruding from the plane of the two-dimensional DNA substrate, and the sequence numbers are Rod-215, Rod-201, Rod-200, Rod-177, Rod-176, The s...

Embodiment 2

[0065] 1. Construction of a 60nm×90nm two-dimensional DNA substrate connected with a single-stranded DNA probe

[0066] The sequences listed in Table 3 were used to replace the corresponding sequences in Table 1 to construct a 60nmx90nm two-dimensional DNA substrate connected with a single-stranded DNA probe. Specifically, the serial numbers in Table 3 are Ball-4, Ball-6, Ball-128, Rod-215, Rod-201, Rod-200, Rod-177, Rod-176, Rod-152, Rod-153 , Rod-123, Rod-13, Rod-119, Rod-18, Rod-116, Rod-24 and Rod-112 sequences respectively replace the sequence numbers in Table 1 as 4, 6, 128, 215, 201, 200, 177, 176, 152, 153, 123, 13, 119, 18, 116, 24, and 112, based on the same method as the above method for constructing a 60 nm × 90 nm substrate to construct a 60 nm × 90 nm substrate with a single-stranded DNA probe attached Dimensional DNA substrate. Therefore, on the constructed two-dimensional DNA substrate, there are connected single-stranded DNA probes protruding from the plane ...

Embodiment 3

[0077] 1. Construction of a 60nm×90nm two-dimensional DNA substrate connected with a single-stranded DNA probe

[0078] Each sequence listed in Table 4 was used to replace the corresponding sequence in Table 1 to construct a 60 nm×90 nm two-dimensional DNA substrate connected with a single-stranded DNA probe. Specifically, use the serial numbers in Table 4 as Ball-4, Ball-6, Ball-128, Rod-215, Rod-201, Rod-200, Rod-177, Rod-176, Rod-152, Rod-153 , Rod-31, Rod-32, Rod-55, Rod-56, Rod-79, Rod-80 and Rod-102 respectively replace the sequence numbers in Table 1 as 4, 6, 128, 215, 201, 200, 177, 176, 152, 153, 31, 32, 55, 56, 79, 80, and 102, based on the same method as the above-mentioned method for constructing a 60 nm × 90 nm substrate to construct a 60 nm × 90 nm substrate with a single-stranded DNA probe attached. Dimensional DNA substrate. Therefore, on the constructed two-dimensional DNA substrate, there are connected single-stranded DNA probes protruding from the plane of...

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Abstract

The invention provides a method for constructing a nanoparticle-nanorod composite structure and a constructed composite structure. The method comprises the following steps that a, a two-dimensional DNA base is constructed; b, modification is conducted on nanoparticles through single-stranded DNA, and single-stranded DNA different from the single-stranded DNA modifying the nanoparticles modifies a nanorod; c, the nanoparticles and the nanorod modified by the single-stranded DNA are crossbred with the two-dimensional DNA base, and the nanoparticle-nanorod composite structure is formed on the two-dimensional DNA base, wherein a single-stranded DNA probe complementary with the single-stranded DNA modifying the nanoparticles and the nanorod and stretching out of the two-dimensional DNA base plane is connected to the two-dimensional DNA base, and a single-stranded DNA probe complementary with the single-stranded DNA modifying the same nanorod is composed of a plurality of single-stranded DNA probes arranged in a linear mode on the two-dimensional DNA base. The method for constructing the nanoparticle-nanorod composite structure can accomplish the controllable operation of the nanorod, and therefore the needed nanoparticle-nanorod composite structure can be constructed.

Description

technical field [0001] The present invention relates to a method for constructing a composite structure of nanoparticles and nanorods, in particular to a method for constructing a composite structure formed of nanoparticles and nanorods based on DNA, as well as nanoparticles and nanorods constructed by the method. Rod combination structure. Background technique [0002] Since Seeman first proposed in 1982 that branched DNA molecules with complementary cohesive ends can be used to construct two-dimensional ordered arrays, DNA nanotechnology has developed vigorously. In 1993, the first DNA double-crossover structure (DNA double-crossover, DNA DX) was born, which can successfully self-assemble into a series of two-dimensional arrays [Seeman, N.C.Biochemistry1993,32:3211]; in 1999, Holliday crossover (Holliday junction) reported and constructed parallelogram DNA structural units, which can self-assemble to form DNA two-dimensional arrays with diamond-shaped holes [Seeman, N.C.J...

Claims

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Application Information

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IPC IPC(8): B82B3/00B82B1/00B82Y40/00
Inventor 王强斌陈中
Owner SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI
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