Treatment for peanut allergy
A technology for peanut allergy and peanut powder, applied in allergic diseases, antibody medical ingredients, medical preparations containing active ingredients, etc., can solve problems such as increased risk of unintentional ingestion
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[0104] experiment
[0105] method 1
[0106] The study was approved by the Local Ethics and Research and Development Committees and written informed consent was given to each family. Inclusion criteria were positive peanut oral (immunization) challenge and presence of peanut-specific IgE in children 4-18 years of age. Severe immunodeficiency and inability to comply with the study protocol were exclusion criteria. 22 children were selected. Children with a history of anaphylaxis following peanut ingestion were included.
[0107] Skin prick test (SPT) (peanut extract, saline negative control and histamine 10mg / mL positive control; single point lancet; ALK-Abello, Denmark ), peanut SPT was interpreted as positive when the wheal diameter was at least 3 mm larger than the negative control. Serum analysis was performed for whole peanut and Ara h2-specific IgE (CAP-Systems FEIA; Phadia, Uppsala, Sweden).
[0108] Double-blind placebo-controlled food challenge (DBPCFC)
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