Application of hydrogen sulfide and donor thereof sodium hydrosulfide to preparation of medicament for treating diabetes
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- FUDAN UNIV
- Publication Date
- 2014-03-12
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Abstract
Description
technical field
[0001] The invention belongs to the field of medicine and pharmacy, and relates to the new medicinal application of hydrogen sulfide and its donor sodium hydrosulfide in pharmacy, in particular to the application of hydrogen sulfide and its donor sodium hydrosulfide in the preparation of medicines for treating diabetes. The hydrogen sulfide and its donor sodium hydrosulfide can be used as an insulin sensitizer and a drug for lowering blood sugar and increasing insulin level for type II diabetes. Background technique
[0002] The prior art discloses hydrogen sulfide (H 2 S) is a metabolite of cysteine in the human body. Its content in the human body is very low, about 20-50 μmol / L, and it is not easy to be controlled artificially. It is also reported in the literature that H 2 S is a new type of endogenous gas molecule involved in the regulation of cardiovascular activity, and has the purpose of promoting angiogenesis in cardiovascular diseases.
[0003] A...