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Rat lower extremity osteoradionecrosis model construction device

A radioactive bone and lower extremity technology, applied in the medical field, can solve the problems of unregistered radiotherapy devices, etc., and achieve the effect of easy promotion and use, convenient use and low cost

Inactive Publication Date: 2016-03-30
SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the advancement of radiotherapy technology, the radiotherapy device has changed from cobalt-60 to a linear accelerator, but domestic and foreign literature has not reported a radiotherapy device using a linear accelerator to construct a rat lower limb ORN model

Method used

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  • Rat lower extremity osteoradionecrosis model construction device
  • Rat lower extremity osteoradionecrosis model construction device
  • Rat lower extremity osteoradionecrosis model construction device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 15

[0016] Embodiment 1.5 rat lower extremity osteoradionecrosis model construction device

[0017] Such as figure 1 As shown, the device includes a cuboid 1 with an open upper bottom and two lead plates (not shown in the figure), the lower bottom of the cuboid 1 is divided into three areas, the first area 11 is the rat body placement area, which is Protected area, the second area 12 is the radiotherapy area, and the third area 13 is the claw pulling area, which is also the protected area. The above three areas are separated by two partitions 14 respectively, and each partition 14 is close to the lower bottom surface. 5 semicircle-shaped holes 141 are arranged in the area, and protrusions 15 are arranged at the place corresponding to the semi-circle-shaped holes 141 in the third area 13, so that the protrusions 15 and the semi-circle-shaped holes 141 are distributed on a straight line; the two pieces of lead One plate just covers the first area 11 and the other just covers the th...

Embodiment 26

[0025] Embodiment 2.6 type rat lower extremity osteoradionecrosis model construction device

[0026] The device structure is the same as in Example 1, the length of the cuboid is 40cm, the width is 30cm, and the height is 5cm, wherein the width of the first area is 16cm, the width of the second area is 6cm, the width of the third area is 8cm, and the height of the partition is 5cm .

[0027] The radius of the semicircular hole is 3cm, and the distance between each hole is 4cm. There are six semi-arc-shaped openings 141 on the partition 14 , corresponding to six protrusions 15 on the third area 13 .

[0028] The lead plate just covers the first area 11 and the third area 13, and the size of one piece is 40 cm long and 16 cm wide, and the size of the other piece is 40 cm long and 8 cm wide.

[0029] This device can simultaneously construct 6 rat lower limb ORN models.

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Abstract

The invention provides a mouse lower-limb radioactivity osteoradionecrosis (ORN) model construction device which includes a cuboid with an open upper bottom face, and two lead plates. A lower bottom face of the cuboid is divided into three areas, wherein the first area is a mouse body placing area; the second areas is a radiotherapy area; the third are is a claw-part pulling area; the three areas are separated by two baffles; a plurality of semi-circular-arc holes are arranged in an area of each baffle, close to the lower bottom face; and projections are arranged at positions of the third area, corresponding to the semi-circular-arc holes so that the projections and the semi-circular-arc are distributed at the same line. The size of the mouse lower-limb radioactivity ORN model construction device undergoes a plurality of tests and division of the three areas is precise and accurate so that healthy tissue of mouse non-radiotherapy areas can be protected effectively and thus mouse ORN model construction is helped. The device is capable of performing construction of a plurality of mouse lower-limb ORN models at the same time so that model construction time is saved and radiotherapy cost is also saved.

Description

technical field [0001] The invention relates to the medical field, in particular to a device for constructing a rat lower limb radioactive osteonecrosis model. Background technique [0002] In the treatment of head and neck tumors, radiation therapy is commonly used as an adjuvant surgical treatment, often concurrently with chemotherapy, and can also provide a palliative treatment for advanced or unresectable tumors. However, when radiation acts on tumor cells, it can also kill normal tissue cells. The most serious clinical complication is osteoradionecrosis (ORN). However, there is currently a lack of effective means for the treatment of ORN. Therefore, it has certain clinical significance and scientific value to construct an ORN animal model to study the effective treatment of ORN. [0003] Since radiation has a damaging effect on normal tissues, it plays an important role in the protection of other parts during the construction of the ORN model of rat lower limbs. Wit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N5/00
Inventor 邹多宏张志愿吴轶群蒋欣泉何悦王绍义
Owner SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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