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A kind of woody extract and its preparation method and application

A woody incense and percolation extraction technology, applied in the directions of drug combination, pharmaceutical formulation, plant raw materials, etc., can solve the problems such as reports on the anti-senile dementia of woody incense and its extracts that have not been seen.

Inactive Publication Date: 2016-05-04
INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] There is no report on the anti-senile dementia of woody fragrance and its extract

Method used

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  • A kind of woody extract and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Embodiment 1: the petroleum ether extract of woody fragrance

[0062] Grind and pass through a 35-mesh sieve with a particle size of 500 μm. Weigh 500 grams of crushed Akiras, first soak it in 1500 ml of petroleum ether for 24 hours, then use petroleum ether to filter and extract until the color of the extract is light, and collect 1500 ml of percolate. The petroleum ether was evaporated to dryness and concentrated to dryness under reduced pressure to obtain 32.7 g of petroleum ether extract (the yield was 6.54%).

Embodiment 2

[0063] Embodiment 2: the petroleum ether extract of woody fragrance

[0064] Grind and pass through a 45-mesh sieve with a particle size of 350 μm. Weigh 500 grams of the crushed Akira, first soak it in 2500 ml of petroleum ether for 36 hours, then use petroleum ether to filter and extract until the color of the extract is light, and collect 2500 ml of percolate , evaporate petroleum ether to dryness, and concentrate to dryness under reduced pressure to obtain 35.46 g of petroleum ether extract (yield 7.09%).

Embodiment 3

[0065] Embodiment 3: the petroleum ether extract of woody fragrance

[0066] Grind and pass through a 30-mesh sieve with a particle size of 590 μm. Weigh 500 grams of the crushed Akira, soak it in 2000 ml of petroleum ether for 20 hours, then use petroleum ether to percolate and extract until the color of the extract is light, and collect 2500 ml of percolate , evaporate the petroleum ether to dryness, and concentrate to dryness under reduced pressure to obtain 30.13 g of petroleum ether extract (the yield is 6.03%).

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Abstract

The invention relates to a banksia rose extract product, a preparation method and an application. The banksia rose extract product is an ethyl acetate extract product extracted by a petroleum ether extract product of banksia rose and the petroleum ether extract product, the extract product is capable of obviously inhibiting the activity of butyrylcholine esterase in an AD model, and the banksia rose extract product can be used for preparing the medicines for treating senile dementia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract, in particular to a woody extract, a preparation method and application thereof. Background technique [0002] Alzheimer's disease is a neurodegenerative disease that seriously threatens human health. Alzheimer's disease (abbreviated as AD) is a major senile dementia, manifested as memory, comprehension, calculation, judgment, orientation, language, abstract thinking, self-control and other ability impairments, resulting in the loss of independent living and working ability of patients. With the acceleration of social aging, AD has become the fourth leading cause of human death. my country is about to enter an aging society, and the disease is gradually showing a younger trend, and the incidence rate is increasing year by year. [0003] So far there is no effective means to cure Alzheimer's disease, but taking acetylcholinesterase inhibitors (ACHEI) is currently the most effective treatme...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/285A61P25/28
Inventor 陈士林黄林芳王冬梅刘艾林杨大坚徐宏喜卞兆祥陈新滋
Owner INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI