Method for identifying forsythia suspensa derivatives

Abstract

The invention relates to a method for identifying forsythia suspensa derivatives. The method comprises the following steps: (1) directly obtaining the forsythia suspensa derivatives as a forsythia suspensa lignans and phenylethanoid glycoside characteristic extract containing an active component group; (2) carrying out IGD (Integrated Graphics Driver) nuclear magnetic resonance spectroscopy fingerprint spectrum detection on the forsythia suspensa lignans and phenylethanoid glycoside characteristic extract so as to obtain peak intensities of characteristic peaks of a plurality of active components in the characteristic extract according to a fingerprint spectrum; and detecting the peak intensity of the characteristic peak of a standard reference corresponding to each active component in the same manner; (3) obtaining the absolute content of the standard reference by a quantitative analysis means; (4) calculating the content of each active component and the content of the active component group in the forsythia suspensa derivatives in a ratio of the peak intensities of the characteristic peaks and the absolute content. The method provided by the invention can be used for reflecting the lignans and phenylethanoid glycoside compounds contained in the forsythia suspensa derivatives and a ratio of the lignans compounds to the phenylethanoid glycoside compounds, so that the purpose of identifying the quality of the forsythia suspensa derivatives can be realized.

Description

technical field

[0001] The invention belongs to the field of identification of natural medicinal plants, and in particular relates to a method for identifying derivatives of forsythia. Background technique

[0002] Forsythia is one of the traditional Chinese medicines commonly used in clinical practice in China. It is the dried fruit of Forsythia suspensa (Thunb.) Vahl, a plant of the genus Forsythia in the family Oleaceae (Oleaceae). Qingqiao, harvested when the fruit is ripe and yellow in color is called Laoqiao. Forsythia belongs to the Lung, Heart, and Small Intestine Meridians. It is slightly cold in nature and bitter in taste. It has the effects of clearing heat and detoxification, reducing swelling and dispelling stagnation, and evacuating wind-heat [National Pharmacopoeia Committee. Pharmacopoeia of the People's Republic of China 2010 Edition Part One. China Medical Science and Technology Press , 159.]. Its active ingredients are mainly lignans and phenylethanol gl...

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