A kind of traditional Chinese medicine preparation for treating women's climacteric syndrome

A technology for traditional Chinese medicine preparations and syndromes, which is applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, can solve problems such as increased oil secretion, and achieve the effects of improving estradiol levels and relieving vasomotor symptoms.

Active Publication Date: 2016-11-02
广东泰康制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Hormone therapy is currently the most commonly used method for the treatment of menopausal syndrome. The main function of progesterone in hormone replacement therapy is to antagonize the endometrium growth effect caused by estrogen, but progesterone in most estrogen-progestin preparations plays an important role in antagonizing estrogen. At the same time, it will lead to adverse reactions such as breast pain, hirsutism, edema and increased oil secretion.

Method used

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  • A kind of traditional Chinese medicine preparation for treating women's climacteric syndrome

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 Chinese medicine oral liquid

[0025] Weigh 0.38kg of golden retriever dog spine, 0.25kg of salvia miltiorrhiza, 0.18kg of curcuma, 0.24kg of xiaoshenjincao, 0.25kg of dancing grass, 0.30kg of double kidney ginseng, 0.40kg of fried jujube kernel and 16kg of angelica, add water to decoct twice, Add water for the first time to 10 times the weight of the medicinal material, decoct for 2 hours, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5 hours, combine the decoction, and concentrate under reduced pressure at 0.08MPa and 70 °C to 70 °C The relative density is 1.15, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, stand overnight, filter, and concentrate the filtrate to 65% under reduced pressure at 0.08MPa and 65°C The relative density at ℃ is 1.15g / mL. Add water and sucrose to prepare oral liquid.

Embodiment 2

[0026] The preparation of embodiment 2 Chinese medicine oral liquid

[0027] Weigh 0.35kg of golden retriever dog spine, 0.28kg of salvia miltiorrhiza, 0.21kg of curcuma, 0.21kg of xiaoshenjincao, 0.20kg of dancing grass, 0.28kg of double kidney ginseng, 0.38kg of fried jujube kernel and 0.16kg of angelica, add water and decoct twice , add water for the first time to 10 times the weight of the medicinal material, decoct for 2 hours, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5 hours, combine the decoction, and concentrate under reduced pressure at 0.08MPa and 70℃ to 70℃ When the relative density is 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, stand overnight, filter, and the filtrate is concentrated under reduced pressure at 0.08MPa and 65°C to The relative density at 65°C is 1.15g / mL, and it can be made into oral liquid by adding water and sucrose.

Embodiment 3

[0028] The preparation of embodiment 3 Chinese medicine granules

[0029] Weigh 0.40kg of golden retriever dog spine, 0.30kg of salvia miltiorrhiza, 0.20kg of curcuma, 0.18kg of xiaoshenjincao, 0.18kg of dancing grass, 0.28kg of double kidney ginseng, 0.46kg of fried jujube kernel and 0.20kg of angelica, add water and decoct twice , add water for the first time to 10 times the weight of the medicinal material, decoct for 2 hours, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5 hours, combine the decoction, and concentrate under reduced pressure at 0.08MPa and 70℃ to 70℃ When the relative density is 1.20, add 95% (v / v) ethanol to make the alcohol content reach 80% (v / v), stir, let it stand overnight, filter, and concentrate the filtrate under reduced pressure at 0.08MPa and 65°C to The relative density at 65°C is 1.15g / mL, and it can be made into oral liquid by adding water and sucrose.

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating climacteric syndrome of women. The preparation is prepared from raw materials and auxiliary materials. The raw materials comprise the following components in parts by weight: 31-40 parts of cibotium barometz, 25-35 parts of salvia miltiorrhiza, 18-24 parts of curcuma zedoary, 18-24 parts of trifid sopubia herb, 15-25 parts of telegraph plants, 25-33 parts of habenaria dentate, 32-46 parts of fried spina date seed and 12-20 parts of angelica sinensis. The traditional Chinese medicine preparation disclosed by the invention can effectively improve the level of estradiol of women with climacteric syndrome and alleviate vasomotor symptom, autonomic imbalance and psychosomatic manifestations.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating women's climacteric syndrome. Background technique [0002] Menopausal syndrome refers to a period in which women transition from childbearing to old age, and is a period in which ovarian function gradually declines. It usually occurs in perimenopausal or postmenopausal women after the age of 40. Symptoms last for 1 to 2 years, sometimes as long as 5 to 10 years. Menopause is an important sign. During this period, the secretion of sex hormones in women decreases or the ratio is out of balance, and a syndrome mainly of autonomic dysfunction appears. The etiology and pathogenesis are relatively complicated. It is related to genetics and immune damage. [0003] Menopausal syndrome mainly manifests as a series of abnormal phenomena such as fatigue, emotional instability, insomnia, dreaminess, memory loss,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P15/12
Inventor 赵雪珍苗华艳
Owner 广东泰康制药有限公司
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