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Precision photodynamic therapy system

A technology of photodynamic therapy and detection system, applied in the directions of therapy and radiation therapy, can solve the problems of incomplete treatment, excessive light, poor treatment effect, etc., and achieve the effect of precise photodynamic therapy

Inactive Publication Date: 2014-07-23
TIANJIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Uniform irradiation makes the serious part of the lesion not receive enough light, resulting in incomplete treatment and poor treatment effect
At the same time, the light-colored parts are exposed to too much light, which will cause certain damage to the skin.

Method used

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  • Precision photodynamic therapy system

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Experimental program
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Effect test

Embodiment Construction

[0015] The photodynamic therapy system provided by the present invention adopts a digital micromirror device (DMD), which relies on the rotation of the micromirror for imaging. Each pixel has a rotatable micromirror. The position of the micromirror is different, and the exit angle of the reflected light is different. Therefore, each micromirror is equivalent to an optical switch. When the optical switch is in the "on state", the reflected light can be projected onto the "screen" through the projection lens, and a bright state appears on the "screen"; when the switch is in the "off state", the reflected light cannot be projected on the "screen", A dark state appears on the "screen". The required light dose is calculated by the tissue optical forward model, and the light dose is accurately delivered by computer-controlled DMD.

[0016] The whole process of treatment using the treatment system of the present invention is as follows: figure 2 As shown, the schematic diagram of ...

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Abstract

The invention relates to a precision photodynamic therapy system which comprises an intravenous device use for injecting photosensitizer to the human body and a laser used for the illuminating nevus flammeus lesion portion of the human body. The photodynamic therapy system further comprises a digital micromirror device, a weak light detection system and a computer, wherein the weak light detection system is used for motivating and measuring the fluorescence-emission of the photosensitizer and organization spectrum through ultraviolet, and transmitting the detection information to the computer; the computer is used for calculating the concentration distribution of the photosensitizer in an organization according to the detection information, and generating a control signal for controlling the digital micromirror device; the digital micromirror device is used for adjusting the optical intensity distribution iradiated by the laser on the lesion portion under the control of the computer. By means of the precision photodynamic therapy system, the precision light dose delivery can be achieved, treatment effect is improved, and side effects are reduced.

Description

technical field [0001] The system belongs to the technical field of photodynamic therapy equipment, and relates to the combined use of a digital micromirror device and a photodynamic therapy instrument. Background technique [0002] Port-wine stain, also known as port-wine stain, is a relatively common congenital vascular malformation mainly in the superficial dermis with low blood flow. Histologically, it is characterized by dilated capillaries or small blood vessels in the papillary or reticular dermis, which can invade the superficial layers of the subcutaneous tissue, but there is no vascular endothelial cell proliferation. The disease often occurs in the face and neck, and is most common in the distribution of the trigeminal nerve, which seriously affects the patient's appearance, causes severe psychological pressure on the patient, and may affect the patient's character development. Therefore, the patient's desire to seek treatment is very urgent. [0003] At present,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/067
Inventor 赵会娟王爽李娇高峰
Owner TIANJIN UNIV
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