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Application of Chamagus Extract in the Preparation of Antitumor Drugs

A technology of anti-tumor drugs and extracts, applied in the field of preparation of anti-tumor drugs, can solve the problems of no active ingredients and anti-tumor, achieve good application prospects, inhibit tumor growth, and have low toxicity effects

Active Publication Date: 2017-02-15
XINJIANG INST OF MATERIA MEDICA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are few research reports on Xinjiang Qiamagu, and there is no research on its active ingredients and anti-tumor aspects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Example 1, the application of Chamagus extract in the preparation of antitumor drugs.

Embodiment 2

[0016] Example 2, the Qiamagu extract in Example 1 is obtained according to the following steps: the first step is to dry the Qiamagu raw material to obtain a dried raw material, add methanol aqueous solution to the dried raw material, and then heat at a constant temperature. One alcohol precipitation extraction, after one alcohol precipitation extraction and separation in sequence, one extraction solution and one residue are obtained, wherein: the amount of methanol aqueous solution added is 7mL to 11mL of methanol aqueous solution per gram of dry raw material, and the temperature of constant temperature heating is 80°C, the heating time is 0.5 hours to 1.5 hours; the second step is to add methanol aqueous solution to the primary residue and then heat at a constant temperature for secondary alcohol precipitation extraction, followed by secondary alcohol precipitation extraction and separation to obtain the secondary extract , wherein: the amount of methanol aqueous solution ad...

Embodiment 3

[0017] Example 3, as a preference of the above example, each gram of Chamagus extract contains 13.90 μmol to 17.15 μmol of glucosinolate.

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PUM

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Abstract

The invention relates to the technical field of application to the preparation of antitumor drugs, and particularly relates to an application of a Qamgur extract to the preparation of antitumor drugs. In the invention, the Qamgur extract is applied to the technical field of preparation of antitumor drugs for the first time; with an effect of suppressing the tumor growth, the Qamgur extract has a good application prospect in the field of preparation of antitumor drugs; meanwhile, the Qamgur extract has relatively low toxicity, and a powerful support is provided for the application of the Qamgur extract to the preparation of antitumor drugs.

Description

technical field [0001] The invention relates to the technical field of application in the preparation of antitumor drugs, and relates to the application of Chamagus extract in the preparation of antitumor drugs. Background technique [0002] Malignant tumors are common and frequently-occurring diseases that seriously endanger human health. The percentage of malignant tumor death among all causes of death accounted for only 12.57% of the total number of deaths in the early 1970s, and the total mortality rate declined after 20 years, while the mortality rate of malignant tumors showed an upward trend, from 1990 to 1992 In 2010, the proportion of malignant tumor deaths rose to 17.94%. In 2000, the proportion of urban malignant tumor deaths in total deaths rose from 16.25% in the early 1970s to 24.38%, which was the first cause of death in the classification of death causes. At the same time, the proportion of rural malignant tumor deaths also increased from 11.53% to 18.3%. C...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/31A61P35/00
Inventor 安熙强张涛马媛向阳向小东赵婷婷程江南胡旭张娟
Owner XINJIANG INST OF MATERIA MEDICA