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Hawthorn fruit lipid lowering tablet and preparation method thereof

A technology of Shanzhuang lipid-lowering tablets and plain tablets, which can be used in pharmaceutical formulations, non-active ingredients of oil/fat/wax, and medical preparations containing active ingredients, etc. Taking and preparing methods are simple, and the effect of good taste

Inactive Publication Date: 2014-09-17
HAINAN HULUWA PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The total amount of drugs used to treat cardiovascular diseases in the world is increasing year by year, and the weight of drugs used to treat hyperlipidemia has increased significantly. Western medicine lipid-lowering drugs have developed rapidly, but their side effects and potential dangers, as well as serious The economic burden has limited the clinical application

Method used

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  • Hawthorn fruit lipid lowering tablet and preparation method thereof
  • Hawthorn fruit lipid lowering tablet and preparation method thereof
  • Hawthorn fruit lipid lowering tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] prescription:

[0034]

[0035] Steps:

[0036] (1) Extraction: Put cassia seeds, hawthorn, and lotus leaves into a multi-functional extraction tank, add water to decoct the prepared materials three times according to the operating procedures (turn on the steam to raise the temperature to boiling, and adjust the steam pressure to about 0.05Mpa), the first Add 8 times the amount of water for the first time, decoct for 1 hour, filter; add 8 times the amount of water for the second time, decoct for 1 hour, filter; add 8 times the amount of water for the third time, decoct for 1 hour, filter Pass. Concentrate the filtrate with a SJN2-2000L double-effect energy-saving concentration tank, control the temperature at 70°C and vacuum degree of 0.06Mpa, and concentrate under reduced pressure to a thick paste (relative density is 1.04). Add 160g of starch, mix well, and dry under reduced pressure (drying temperature 60°C). After drying, it is crushed and passed through a 100...

Embodiment 2

[0040] prescription:

[0041]

[0042] Steps:

[0043] (1) Extraction: Put the cassia seeds, hawthorn, and lotus leaves into the multi-functional extraction tank. Add 8 times the amount of water, decoct for 1 hour, filter; add 8 times the amount of water for the second time, decoct for 1 hour, filter; add 8 times the amount of water for the third time, decoct for 1 hour, and filter. Concentrate the filtrate with a SJN2-2000L double-effect energy-saving concentration tank (relative density is 1.06), control the temperature at 65°C and vacuum degree of 0.07Mpa, and concentrate under reduced pressure to a thick paste. Add 180g of starch, mix well, and dry under reduced pressure (drying temperature 60°C). After drying, it is crushed and passed through a 100-mesh sieve to obtain Shanzhuang Jiangzhi Dry Cream Powder.

[0044] (2) Granulation: Add the pulverized fine powder into a wet mixing granulator and mix for 2 minutes, add 45% ethanol aqueous solution into the wet granula...

Embodiment 3

[0047] prescription:

[0048]

[0049] Steps:

[0050] (1) Extraction: Put the cassia seeds, hawthorn, and lotus leaves into the multi-functional extraction tank. Add 8 times the amount of water, decoct for 1 hour, filter; add 8 times the amount of water for the second time, decoct for 1 hour, filter; add 8 times the amount of water for the third time, decoct for 1 hour, and filter. Concentrate the filtrate with a SJN2-2000L double-effect energy-saving concentration tank, control the temperature at 70°C and vacuum degree of 0.06Mpa, and concentrate under reduced pressure to a thick paste (relative density is 1.10). Add 190g of starch, mix well, and dry under reduced pressure (drying temperature 60°C). After drying, it is crushed and passed through a 100-mesh sieve to obtain Shanzhuang Jiangzhi Dry Cream Powder.

[0051] (2) Granulation: Add the pulverized fine powder into a wet mixing granulator and mix for 2 minutes, add 45% ethanol aqueous solution into the wet granula...

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Abstract

The invention discloses a hawthorn fruit lipid lowering tablet and a preparation method thereof. The hawthorn fruit lipid lowering tablet is prepared by using the following raw materials, by weight, 1000-1500 parts of Semen Cassiae, 500-1000 parts of hawthorn fruit, 300-600 parts of lotus leaf, 100-250 parts of starch, 20-30 parts of a lubricant, 100-400 parts of a syrup, 10-30 parts of carmine, 10-30 parts of Chinese wax and a proper amount of a 40-50% aqueous solution of ethanol. The hawthorn fruit lipid lowering tablet has the advantages of high stability, good mouthfeel, convenient administration and high bioavailability, and the preparation method has the advantages of simplicity, no need of any special equipment, and suitableness for the industrial production.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to Shanzhuang Jiangzhi Tablet and a preparation method thereof. Background technique [0002] With the continuous development of my country's social economy, the change of ecological environment, the increase of people's life and work pressure, the change of dietary structure, and the acceleration of population aging, the incidence of dyslipidemia in people over 30 years old in my country is increasing year by year. Family history of hyperlipidemia, body mass index, smoking and drinking and other unhealthy lifestyles, as well as long-term diets such as insufficient intake of vegetables, fruits, fish, shrimp, beans and milk, excessive intake of livestock, poultry meat and oils Unreasonable structure is an important risk factor for high school blood disease. Hyperlipidemia is a major risk factor for cardiovascular disease and a major killer of human health. [0003] The to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61K47/44A61K9/36A61P3/06
Inventor 刘景萍刘全国陈克领林文君
Owner HAINAN HULUWA PHARMA GRP CO LTD
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