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The use of water glue composition

A composition and application technology, applied in medical science, prosthesis, etc., can solve the problems of poor effect, cell death due to hypoxia, difficult to shape and high bioabsorption, and achieve the effect of slowing down the absorption speed

Inactive Publication Date: 2016-07-13
NAT TAIPEI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Autologous adipose stem cells can grow into individual fat cells in vivo; however, the hyaluronic acid colloid here still cannot solve the problems of not easy to shape and high bioabsorption
Hyaluronic acid colloid may cover autologous adipose stem cells, resulting in cell death due to hypoxia, or unable to contact with body fluids to obtain growth factors
These various problems make the effect of this technology not obvious

Method used

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  • The use of water glue composition
  • The use of water glue composition
  • The use of water glue composition

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0042]

[0043] First, mix polymethylmethacrylate (polymethylmethacrylate, PMMA) microspheres and β-tricalcium phosphate powder, so that the weight concentration of polymethylmethacrylate microspheres in the resulting mixture is 30%, and β-tricalcium phosphate The powder weight concentration is 70%. After the obtained mixture is evenly mixed with an appropriate amount of zirconium balls and 95% alcohol solution, the mixture is wet ground for at least 8 hours. The zirconium balls in the mixture are removed to obtain a mixed slurry. Next, put the mixed slurry in an oven at 60° C. until the solvent in the mixed slurry is completely removed to form a dry powder. Next, the dry powder and polyvinyl alcohol (polyvinylalcohol, PVA) are mixed, so that the weight concentration of the dry powder in the obtained mixture is 97%, and the weight concentration of polyvinyl alcohol is 3%. The resulting mixture was ground and sieved through a 60-mesh sieve to allow the mixture to have an ev...

preparation example 2

[0044]

[0045] The β-tricalcium phosphate carrier and hydrogel composition obtained here was prepared according to the method described in Preparation Example 1, except that the second heating temperature of the block was 1050°C.

preparation example 3

[0046]

[0047] The β-tricalcium phosphate carrier and hydrogel composition obtained here were prepared according to the method described in Preparation Example 1, except that the second heating temperature of the block was 1100°C.

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PUM

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Abstract

The present invention proposes the use of a hydrogel composition for preparing fillers for expanding soft tissues, and the hydrogel composition contains: a porous bioabsorbable ceramic carrier and a hyaluronic acid colloid.

Description

technical field [0001] The present invention relates to the use of a hydrogel composition, in particular to its use for preparing fillers for enlarging soft tissues. Background technique [0002] The 21st century is the era of "biotechnology". The development of human medicine not only pays attention to the treatment and prevention of diseases, but also gradually pays attention to the change of appearance. Plastic surgery and dermatology have become emerging disciplines of human medicine. [0003] The enlargement of soft tissue is commonly seen in plastic surgery or skin surgery. Depending on the material used, it can be divided into "autologous transplant" and "foreign transplant". In autografting, natural soft tissue is removed from one part of an individual and implanted in another part of the same individual. Natural soft tissue is easily absorbed by the individual, and its persistence is not enough. In exogenous transplantation, synthetic soft tissue (or "filler") is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/52A61L27/20A61L27/10A61L27/12A61L27/56A61L27/58A61L27/38
Inventor 杨永钦邓守成许玮玲
Owner NAT TAIPEI UNIV OF TECH