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Formula milk powder used for phenylalanine metabolic block

A technology of phenylalanine and formula milk powder, applied in the directions of milk preparations, dairy products, applications, etc., can solve the problems of lack, affecting the growth and development of infants, neglecting the replacement and supplementation of phenylalanine, and achieve synergistic promotion of digestion and absorption, Ease of processing and preservation, promoting healthy growth

Inactive Publication Date: 2017-09-29
杭州千岛湖康诺邦健康产品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Although consuming phenylalanine-free products can alleviate and assist in the treatment of phenylketonuria, phenylalanine, as an essential amino acid, participates in the body's glucose metabolism and fat metabolism, and its deficiency in the body will affect the growth and development of the baby
However, the existing products only consider the de-phenylalanine of protein, ignoring the replacement supplement of phenylalanine

Method used

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  • Formula milk powder used for phenylalanine metabolic block
  • Formula milk powder used for phenylalanine metabolic block
  • Formula milk powder used for phenylalanine metabolic block

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The phenylalanine barrier-metabolism formula milk powder of this embodiment consists of the following weights: 20% phenylalanine-free amino acids (including 20% ​​L-tyrosine), and 40% vegetable fat powder (where OPO:MCT=2) :3), oligosaccharides 6% (of which xylo-oligosaccharides: raffinose = 1:9), mineral premix 0.3%, vitamin premix 0.1%, calcium carbonate 0.5%, special nutrients 0.5%, Maltodextrin is made up to 100%,

[0038] The content of each energy and premix is ​​(per 100gkJ): energy 315kJ / 100mL, protein 1.4g, fat 1.05g, vitamin A 43μg RE, vitamin D 0.25μg, vitamin E 1.2mgα-TE, vitamin K11μg, vitamin B110μg, vitamin B214μg, vitamin B675μg, vitamin B120.36μg, niacin 70μg, folic acid 12μg, pantothenic acid 70μg, biotin 0.4μg, vitamin C17mg, sodium 5mg, potassium 43mg, magnesium 3.6mg, calcium 12mg, phosphorus 6mg, iron 0.5mg, zinc 0.12 mg, manganese 1.2μg, chlorine 38mg, copper 4.8μg, iodine 14μg, selenium 0.25μg.

Embodiment 2

[0040] The phenylalanine barrier-metabolism formula milk powder of this embodiment is composed of the following weights: 10% phenylalanine-free amino acids (including 50% L-tyrosine), and 53% vegetable fat powder (where OPO:MCT=3) : 2), oligosaccharides 1% (of which xylo-oligosaccharides: raffinose = 1:4.5), mineral premixes 0.1%, vitamin premixes 0.3%, calcium carbonate 0.1%, special nutrients 2%, Maltodextrin is made up to 100%,

[0041] The content of each energy and premix is ​​(per 100gkJ): energy 250kJ / 100mL, protein 0.45g, fat 1.4g, vitamin A 14μg RE, vitamin D 0.75μg, vitamin E 0.12mgα-TE, vitamin K16.5μg, vitamin B172μg , Vitamin B2119μg, Vitamin B68.5μg, Vitamin B120.025μg, Niacin 750μg, Folic acid 1μg, Pantothenic acid 70μg, Biotin 5μg, Vitamin C 1.9mg, Sodium 14mg, Potassium 14mg, Magnesium 1.2mg, Calcium 60mg, Phosphorus 24mg, Iron 0.1mg, zinc 0.6mg, manganese 50μg, chlorine 12mg, copper 29μg, iodine 1.2μg, selenium 1.9μg.

Embodiment 3

[0043] The phenylalanine barrier-metabolism formula milk powder of this embodiment is composed of the following weight: 15% of phenylalanine amino acids (including 35% of L-tyrosine), 46% of vegetable fat powder (where OPO:MCT=4) :3), oligosaccharides 3% (of which xylo-oligosaccharides: raffinose = 1:1), mineral premixes 0.2%, vitamin premixes 0.2%, calcium carbonate 0.3%, special nutrients 1%, Maltodextrin is made up to 100%,

[0044] The content of each energy and premix is ​​(per 100gkJ): energy 270kJ / 100mL, protein 0.6g, fat 1.26g, vitamin A 25μg RE, vitamin D 0.45μg, vitamin E 0.5mgα-TE, vitamin K13μg, vitamin B135μg, Vitamin B240μg, vitamin B620μg, vitamin B120.1μg, niacin 250μg, folic acid 5μg, pantothenic acid 150μg, biotin 1.5μg, vitamin C5mg, sodium 7mg, potassium 19mg, magnesium 1.8mg, calcium 28mg, phosphorus 15mg, iron 0.28mg, zinc 0.3mg, manganese 15μg, chlorine 25mg, copper 12μg, iodine 6μg, selenium 0.8μg.

[0045] 2. Animal testing

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Abstract

The invention discloses a formula milk powder used for phenylalanine metabolic block. The formula milk powder is produced from, by mass, 10-20% of amino acids free from phenylalanine, 40-53% of vegetable fat powder, 1-6% of oligosaccharides, 0.1-0.3% of a mineral matter premix, 0.1-0.3% of a vitamin premix, 0.1-0.5% of calcium carbonate, 0.5-2% of a special nutrient, and the balance of maltodextrin. 1,3-Olein-2-palmitin and medium-chain triglyceride are embedded in a wall material through a microencapsulation technology, so the formula milk powder has a synergistic promotion effect on the amino acid (especially L-tyrosine) digestion and absorption of bodies, and the microencapsulation technology makes the formula milk powder easy to process and preserve, and slows the release and absorption speed of the product in human bodies in order to avoid the stomachache and other problems.

Description

Technical field [0001] The invention belongs to the technical field of functional foods and foods for special medical purposes, and specifically relates to a phenylalanine barrier-metabolism formula milk powder for infants with phenylketonuria. Background technique [0002] Amino acid metabolism disorder is an inherited metabolic disease that does not affect the growth and development of the fetus in the uterus or delivery. The appearance and activities of the baby are normal at birth, and gradually lose intelligence after half or one year of age. [0003] Phenylketonuria (PKU) is one of the most clinically important early childhood amino acid metabolism disorders. It is caused by an enzyme responsible for the metabolism of phenylalanine-liver phenylalanine hydroxylase (PAH). ) Caused by impaired activity. The patient cannot metabolize phenylalanine (Phe) in food protein normally, causing a large amount of Phe and its abnormal metabolites to accumulate in the body, causing brain d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23C9/152A23C9/156A23C9/158A23C9/16
CPCA23C9/152A23C9/1522A23C9/1526A23C9/156A23C9/158A23C9/16
Inventor 邵胜荣胡钢亮孙俊吴芝岳杨娜吴红宇
Owner 杭州千岛湖康诺邦健康产品有限公司
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