A kind of detection method of pharmaceutical composition

A detection method and composition technology, applied in measurement devices, instruments, scientific instruments, etc., can solve problems such as unreasonable wavelength selection, background interference, and large baseline fluctuations.
CN104076099BActive Publication Date: 2016-01-20SICHUAN JISHENGTANG PHARMLS
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN JISHENGTANG PHARMLS
Publication Date
2016-01-20

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Abstract

The invention discloses a method for detection and quality control of a medicine composition. The medicine composition is a composition containing hypericum perforatum, the content of hyperoside, the content of rutin and the content of lilac glycosides are detected through liquid chromatography, and the adopted liquid chromatography determination conditions are characterized in that octadecylsilane chemically bonded silica serves as filler of a chromatographic column, a mobile phase A is a NaH2PO4 buffer solution, a mobile phase B is a mixed solution of acetonitrile and methyl alcohol, and gradient elution is adopted. The method has the advantages of being quick, efficient, stable, accurate and the like, and quality control over the medicine composition can be quickly and effectively conducted.
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Description

Technical field

[0001] The invention relates to the quality control of medicines, in particular to a method for the detection and quality control of a medicine composition. Background technique

[0002] Depression has quickly become the second most important disease in the global disease that poses a serious burden to humans. The suffering caused to patients and their families and the loss to society are unmatched by other diseases. Therefore, the society's demand for drugs for the treatment of depression is huge. Compared with Western medicine using specific target drugs for treatment, Chinese medicine uses active substance groups that can act on multiple targets and present pleiotropic effects, and adjustment is its main mechanism of action, showing the uniqueness of traditional medicine. Shugan Jieyu Capsule is the first Chinese patent medicine approved by SFDA for the treatment of depression in China. It consists of two Chinese medicines: Hypericum perforatum and Acanthopana...

Claims

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