Application of traditional Chinese medicine external-use plaster composition in preparation of drug used for preventing, relieving and/or treating osteoarticular diseases

A bone and joint disease and composition technology, applied in the field of external medicine, can solve problems such as liver and kidney damage, achieve the effects of disease prevention, easy use, and pain relief

Inactive Publication Date: 2014-11-05
吕刚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional non-steroidal anti-inflammatory analgesics (NSA IDs) such as aspirin and corticosteroids are generally used for treatment, but they can easily cause liver and kidney damage

Method used

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  • Application of traditional Chinese medicine external-use plaster composition in preparation of drug used for preventing, relieving and/or treating osteoarticular diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0130] The traditional Chinese medicine ointment for external use prepared in Example 1 is made into a plaster and pasted on the affected part, one paste each time, once a day.

[0131] Positive control drug: Gutong plaster, Guilin Tianhe Pharmaceutical Co., Ltd., production batch number: 20121009, size 7cm×10cm×10 patches.

[0132] For external use, tear off the whole piece and stick it on the affected area so that the elastic direction of the elastic cloth is consistent with the direction of joint movement; 1 patch each time, 7 days as a course of treatment; or follow the doctor's advice.

[0133] 3.2 Experimental method

[0134] Take 60 male SD rats, except for 10 blank control groups, the other animals were fasted for 12 hours before the operation, anesthetized with about 10% chloral hydrate intraperitoneal injection, centered on the spinous process of the 55th lumbar vertebra (L5) and taken longitudinally in the middle of the back An incision was made, and the skin and s...

Embodiment 2

[0194] 1) Weigh the raw materials according to the following ratio (unit: ×100g)

[0195] Rehmannia 20, Radix Radix 30, Rhizoma Drynaria 30, Panax notoginseng 40, Peach Kernel 20, Rehmannia Rehmanniae 15, Bletilla striata 20, Guangui 30, Angelica dahurica 35, Angelica 30, Radix Paeoniae Rubra 45, Notopterygium 20, Sophora flavescens 30, Licorice 25, Duhuo 20. Yuanshen 15, Rhubarb 25, Turtle Turtle 35, Huang Dan 20, Cucumber Seed 10, Leek Seed 30, Grape Seed 30, Green Peel 30

[0196] Among them, Shengdi, Baishui, Drynaria, Panax notoginseng, peach kernel, Rehmannia glutinosa, Bletilla striata, Guangui, Baizhi, Angelica, Chishao, Qianghuo, Sophora flavescens, licorice, Duhuo, Yuanshen, rhubarb, and Turtle are crushed into fine powder , the particle size of the fine powder is 200-300 mesh, mix evenly, and prepare the first fine powder mixture for later use;

[0197]Grinding the raw materials cucumber seeds, leek seeds, grape seeds and green peels into fine powder respectively t...

Embodiment 3

[0204] 1) Weigh the raw materials according to the following ratio (unit: ×100g)

[0205] Rehmannia 30, Radix Radix 35, Rhizoma Drynaria 20, Panax notoginseng 60, Peach Kernel 30, Rehmannia Rehmanniae 10, Bletilla striata 35, Guangui 20, Angelica dahurica 20, Angelica 35, Radix Paeoniae Rubra 30, Notopterygium 15, Sophora flavescens 15, Licorice 15, Duhuo 30. Yuanshen 35, Rhubarb 10, Turtle 45, Huang Dan 40, Cucumber Seed 15, Leek Seed 20, Grape Seed 20, Green Peel 40

[0206] Among them, the raw ground, white pomegranate, drynaria, notoginseng, peach kernel, rehmannia, bletilla striata, official osmanthus, angelica, angelica, red peony root, notopterygium, flavescens, licorice, lovage, root ginseng, rhubarb, and soft-shelled turtle are crushed into fine Powder, fine powder particle size is 200-300 mesh, mix evenly, make the first fine powder mixture and set aside;

[0207] Grinding the raw materials cucumber seeds, leek seeds, grape seeds and green peels into fine powder res...

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Abstract

The invention discloses an application of an external-use plaster composition in preparation of a drug used for preventing, relieving and/or treating osteoarticular diseases. A experiment proves that the external-use plaster composition is significant in effects on treatment of osteoarticular diseases, is quick in the effects, is slight in toxic and side effects, is simple in preparation process, is a drug for preparing the drug used for treating osteoarticular diseases safely, high-efficiently and stably, is suitable for industrial production, is easy to popularize. The invention provides a new drug source for preventing and treating the osteoarticular diseases.

Description

technical field [0001] The invention relates to a medicine for external use and its application, in particular to a traditional Chinese medicine ointment composition for external use and its application in preparing medicine for treating bone and joint diseases. Background technique [0002] Bone and joint diseases, including degenerative arthritis, bursitis, synovitis, cervical spondylosis, lumbar spondylosis, frozen shoulder, hyperosteogeny, rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, frozen shoulder , femoral head necrosis, etc., the root cause of the disease is not bone disease, modern medical research has found that the root cause of the disease lies in the loss of joint protection ability of the "joint protection system" such as cartilage! The World Health Organization lists bone and joint diseases as the diseases that most harm the human body after cardiovascular and cerebrovascular diseases, cancer, and diabetes, the "three major killers". [0003] T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P19/02A61P19/08A61K33/24
Inventor 吕刚佟玉兰
Owner 吕刚
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