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Medicament containing taraxacum plant root extract for treatment or prevention of cancer, and method for preparing same

An extract, the technology of dandelion, which is applied in the field of medicine containing dandelion plant root extract and its preparation for the treatment and prevention of cancer, can solve the problems of cell death, low anticancer activity, etc.

Inactive Publication Date: 2014-12-10
UNIVERSITY OF WINDSOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

It has been recognized that this traditional form of dandelion extract is generally associated with lower anticancer activity, with 10% cell death when introduced into cancerous or tumor tissue

Method used

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  • Medicament containing taraxacum plant root extract for treatment or prevention of cancer, and method for preparing same
  • Medicament containing taraxacum plant root extract for treatment or prevention of cancer, and method for preparing same
  • Medicament containing taraxacum plant root extract for treatment or prevention of cancer, and method for preparing same

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Embodiment Construction

[0112] According to a preferred embodiment of the present invention, root extracts of plants of the genus Taraxacum for treating and / or preventing tumors are prepared. To prepare a preferred root extract of Dandelion plants, Dandelions of the species Dandelion are collected in Ontario, Canada about 30 days before spring flowering and just at the beginning of autumn. The harvested plants are washed in water and the base of the stems are cut off to obtain the roots. The harvested roots are then cut into slices approximately 1 / 4" long lengthwise.

[0113] Submerge the cut root slices in liquid nitrogen for approximately 5-10 minutes until completely frozen. Frozen sections were ground in an impact mill to an average particle size of approximately less than 45 [mu]m. Soak the ground roots in boiled distilled water for 1 hour to dissolve the active compounds.

[0114] After the extraction / dissolution step, the distilled water containing the active compound is vacuum filtered thr...

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Abstract

The present invention relates to an improved method for preparing a medicament comprising a Taraxacum plant root extract for the treatment or prevention of a cancer. In one aspect, the method comprises freezing Taraxacum plant root to obtain a frozen root stock, said freezing step being selected to effect at least partial disruption of one or more root cells; dry grinding the frozen root stock to obtain a ground root powder, wherein during said dry grinding step the frozen root stock is maintained at a grinding temperature below about 40°C; steeping the ground root powder with a solvent to obtain a suspension having a liquid extract portion and a solid particle portion; and separating the liquid extract portion from the solid particle portion to provide a separated liquid extract for use in the medicament.

Description

[0001] related application [0002] This application is entitled to the benefit of U.S. Provisional Patent Application Serial No. 61 / 597,453, filed February 10, 2012, under 35 U.S.C. 119(e). technical field [0003] The present invention relates to an improved method for preparing a medicine comprising a root extract of a plant belonging to the genus Taraxacum, which can be used for treating, improving or preventing cancer. In particular, the present invention relates to the preparation of a pharmaceutical composition comprising an extract of the root of the dandelion plant, for the treatment and / or prevention of cancer, and preferably colorectal cancer, pancreatic cancer, skin cancer such as melanoma, and blood cancer, such as chronic Lymphoblastic leukemia, chronic myeloid leukemia, chronic monocytic myelogenous leukemia, and Hodgkin's lymphoma. Background technique [0004] Dandelion (Taraxacum), also commonly known as dandelion, belongs to the family Asteraceae. These...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/288A61P35/00
CPCA61K2236/15A61K36/288A61P35/00A61P35/02A61K45/06
Inventor 希亚朗·潘迪卡罗琳·玛丽·哈姆帕梅拉·乌祖阿左·欧瓦杰
Owner UNIVERSITY OF WINDSOR
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