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Composition for promoting increase of subcutaneous tissue and subcutaneous fatty tissue

一种皮下组织、组合物的技术，应用在药物组合、组织再生、皮肤疾病等方向，能够解决不实用等问题，达到效果大、促进皮下组织形成、促进脂肪合成的效果

Active Publication Date: 2014-12-24
山川 谦辅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This improvement of skin problems is aimed at improving dryness of the skin mainly due to aging, such as wrinkles and sagging, and a reduction in elasticity. For example, there is still room for application to breast augmentation, but plasma separated as PRP is About one-tenth to one-twentieth of the blood volume of blood collection, if you want to get 40mL of PRP, you need a maximum of 400-800mL of blood
Therefore, the PRP that can be used is at most a few mL to at most 40 mL, which is not practical for breast enhancement that requires tens to hundreds of mL. There is no research on whether the breast enhancement method using PRP is effective for breast enhancement.

Method used

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  • Composition for promoting increase of subcutaneous tissue and subcutaneous fatty tissue
  • Composition for promoting increase of subcutaneous tissue and subcutaneous fatty tissue
  • Composition for promoting increase of subcutaneous tissue and subcutaneous fatty tissue

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] Example 1: Manufacture of a composition for breast enhancement comprising a subcutaneous tissue increase promotion composition

[0072]

[0073] For blood collection, 2.5 mL of sodium heparin (10 units / mL) was added to a syringe with a volume of 50 cc, and 50 mL of blood was collected. As a total amount, 220 to 300 mL of blood was collected. The collected blood was centrifuged (combination of KUBOTA 2420 and KUBOTA RS-240 (rotor): 4000 rpm / 10 minutes) to separate plasma.

[0074] 25 mL of the separated plasma was collected into a 50 cc syringe to obtain heparin-added plasma.

[0075] In the case of obtaining self-derived heated plasma, after obtaining the heparin-added plasma, the heparin-added plasma was subjected to 10 minutes at 100° C. Heat treatment, then rapid cooling. The result is gelatinous self-derived heated plasma.

[0076]

[0077] A traferamine (registered trademark) preparation (recombinant basic fibroblast growth factor: b-FGF: Science Research Ph...

Embodiment 2

[0082] Example 2: A specific administration example of a composition for breast enhancement comprising a subcutaneous tissue increase promoting composition (case 1)

[0083] Sufficient informed consent was given in advance, and the composition for breast enlargement of the present invention was administered to a 45-year-old woman who obtained the consent, and the effect of breast enlargement was confirmed.

[0084] Using the composition for breast enlargement containing the subcutaneous tissue increase promotion composition produced according to the above-mentioned Example 1, a mixture of Traferamine, Intralipid (fat emulsion), and self-derived plasma added with heparin was administered to the mammary gland five times between the pectoralis major fascia.

[0085] For the first to third times, 50 mL on one side and a total of 100 mL were administered, and for the fourth and fifth times, 100 mL on one side and a total of 200 mL were administered. The fat emulsion concentratio...

Embodiment 3

[0089] Example 3: A specific administration example of a composition for breast enhancement comprising a subcutaneous tissue increase promoting composition (case 2)

[0090] Sufficient informed consent was obtained in advance, and the composition for breast enlargement of the present invention was administered to a 36-year-old woman who obtained the consent, and the effect of breast enlargement was confirmed.

[0091] First, it was determined which factor was necessary among traferamine, fat emulsion (Intralipid), and heparin-added self-derived blood plasma mixture constituting the breast enhancement composition of the present invention.

[0092] First, the composition for breast enlargement containing the subcutaneous tissue increase promoting composition of the present invention containing a mixture of traferamine containing traferamine and heparin added with fat emulsion (Intralipid) was administered 3 times. As a result, the length of the upper bust was increased by abou...

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Abstract

Provided are: particularly a composition for enlarging the breast, which comprises a composition for promoting the increase in a subcutaneous tissue, wherein the latter composition enables the recovery of an autologous tissue or the recovery of physical appearance through such a safe and natural method that an adipose tissue is formed and increased around a mammary gland to accumulate and increase the adipose tissue under the skin of the breast; and a breast enlargement method. A composition for promoting the increase in a subcutaneous tissue, particularly a composition for enlarging the breast, which is characterized by comprising self-derived plasma and a basic fibroblast proliferation factor (b-FGF); a composition for enlarging the breast, which comprises the above-mentioned composition for promoting the increase in a subcutaneous tissue, wherein the composition additionally comprises a fat, specifically a composition for enlarging the breast which comprises the above-mentioned composition for promoting the increase in a subcutaneous tissue, wherein the fat has the form of a fat emulsion and the fat emulsion has the form of an oil-in-water-type fat emulsion that is produced by emulsifying an oil or fat in the presence of an emulsifying agent; a method for enlarging the breast, in which the composition is used; and a unit for injecting the composition for enlarging the breast.

Description

technical field [0001] The present invention relates to a composition for promoting accumulation of subcutaneous tissue and adipose tissue, and enlarged subcutaneous tissue under the skin of breasts and the like by generating and increasing subcutaneous tissue or adipose tissue around mammary glands and the like. Background technique [0002] Women's breasts are mainly composed of mammary glands and adipose tissue. The volume of breasts varies greatly from person to person and easily changes with weight gain or loss. It is known that in healthy women, the volume (size) of breasts depends on the volume of adipose tissue. capacity varies. [0003] It is known that the fat metabolism of fat cells constituting adipose tissue differs depending on the body part. Among them, breasts are characterized by low fat synthesis and high fat differentiation compared with lower legs. Therefore, in order to maintain plumpness It is expected to promote fat synthesis in fat cells, promote the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/16A61K9/10A61K31/22A61K38/00A61L27/00A61P17/00A61K8/06A61K8/37A61K8/64A61K8/98A61L27/22A61L27/36A61L27/54A61Q19/00
CPCA61K9/0041A61K9/107A61L27/227A61L27/3616A61L27/54A61L2300/414A61L2430/34A61K38/1825A61K35/16A61P17/00A61K2300/00A61K31/22A61K38/22
Inventor 山川谦辅
Owner 山川 谦辅
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