Traditional Chinese medicine compound spray for treating rhinitis

A technology for treating rhinitis and traditional Chinese medicine, which is applied in the direction of medical formula, drug combination, drug delivery, etc. It can solve the problems that sprays are rarely used in the treatment of rhinitis, and achieve the effects of promoting microcirculation, no toxic side effects, and preventing infection

Active Publication Date: 2015-01-28
KUNMING UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the medicaments for the treatment of rhinitis sold on the market are mostly tablets, pills, capsules, oral liquids, plasters, ointments, etc., and the use of sprays in the treatment of rhinitis is still relatively rare

Method used

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  • Traditional Chinese medicine compound spray for treating rhinitis
  • Traditional Chinese medicine compound spray for treating rhinitis
  • Traditional Chinese medicine compound spray for treating rhinitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: a kind of Chinese medicine compound spray for controlling rhinitis, composition and percentage by weight are: sodium fulvic acid 10%, total alkaloids 5% of Uncaria vine, 6% of volatile oil of bamboo leaves, 6% of volatile oil of Kuding, 7% volatile oil of Gentiana chinensis, 7% volatile oil of Nepeta yunnanensis, 2% fatty alcohol polyoxyethylene ether, 0.4% ethyl p-hydroxybenzoate, 0.08% Tween-80, 0.4% peppermint essential oil, and the rest is water.

[0035] The preparation method of the above-mentioned Chinese medicine compound spray for treating rhinitis comprises the steps:

[0036] 1) The extraction process of the total alkaloids of Uncaria is as follows:

[0037] The total alkaloids of Uncaria can be prepared by referring to the method in the patent application CN201110266531 "Preparation method of total alkaloids of Uncaria".

[0038] 2) The preparation process of the volatile oil from the leaves of light bamboo is as follows:

[0039]Wei...

Embodiment 2

[0068] Embodiment 2: a kind of Chinese medicine compound spray for controlling rhinitis, composition and percentage by weight are: sodium fulvic acid 5%, total alkaloids 3% of Uncaria vine, 5% of volatile oil of bamboo leaves, 3% of volatile oil of Kuding, 4% volatile oil of Gentiana chinensis flower, 5% volatile oil of Nepeta yunnanensis, 1% alkylphenol polyoxyethylene ether, 0.1% benzyl alcohol, 0.05% fatty acid polyoxyethylene ester, 0.1% lemon essential oil, and the rest is water.

[0069] The preparation method of the above-mentioned Chinese medicine compound spray for treating rhinitis is the same as in Example 1.

[0070] The acute rhinitis model experimental method of present embodiment medicine is with embodiment 1, and result is as follows:

[0071] Table 4: Effects of topical sprays on ear swelling in mice

[0072]

[0073] Compared with normal saline group, *P<0.05 (t-test); **P<0.01 (t-test)

[0074] The chronic rhinitis model experimental method of present ...

Embodiment 3

[0083] Embodiment 3: a kind of traditional Chinese medicine compound spray that is used to control rhinitis, composition and percentage by weight are: sodium fulvic acid 8%, total alkaloids 4% of Uncaria uncariae, 5% of volatile oil of bamboo leaf, 5% of volatile oil of Kuding, 6% volatile oil of Gentiana chinensis flower, 6% volatile oil of Nepeta yunnanensis, 1% sodium alkyl sulfosuccinate, 0.2% phenylethyl alcohol, 0.07% polyoxyethylene fatty acid ester, 0.2% lotus leaf essential oil, and the rest is water.

[0084] The preparation method of the above-mentioned Chinese medicine compound spray for controlling rhinitis is the same as Example 1;

[0085] The acute rhinitis model experimental method of present embodiment medicine is with embodiment 1, and result is as follows:

[0086]Table 7: Effects of topical sprays on ear swelling in mice

[0087]

[0088] Compared with normal saline group, * P<0.05 (t-test); **P<0.01 (t-test);

[0089] The chronic rhinitis model expe...

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Abstract

The invention discloses a traditional Chinese medicine compound spray for treating rhinitis. The traditional Chinese medicine compound spray is prepared from the following raw materials in percentage by weight: 5%-15% of fulvic acid or sodium fulvate, 3%-8% of uncaria volatile oil, 5-7% of lophatherum gracile volatile oil, 3%-8% of formosan lattuce herb volatile oil, 4-8% of volatile oil of hemp flowers and gentiana macrophylla flowers, 5-8% of Yunnan fineleaf schizonepeta herb volatile oil and the balance of auxiliaries. Compared with an existing preparation for treating the rhinitis, the traditional Chinese medicine compound spray is capable of effectively treating nasal diseases such as chronic rhinitis, acute rhinitis and nasosinusitis; experiments prove that the traditional Chinese medicine compound spray is good in effect, and also has the effects of resisting bacteria and viruses, clearing heat, freeing orifices, activating blood, arresting bleeding and coagulating blood, promoting capillary regeneration and the like while treating the rhinitis; the traditional Chinese medicine compound spray is used for effectively reducing the side effects of drug-induced nasal diseases; fulvic acid or sodium fulvate, the total alkaloids of the uncaria, the lophatherum gracile volatile oil, the formosan lattuce herb volatile oil, the volatile oil of the hemp flowers and the gentiana macrophylla flowers and the Yunnan fineleaf schizonepeta herb volatile oil are taken as the major effective components of the spray, and the spray has the advantages of reasonable formula, simple combination, wide medicinal material source and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a compound traditional Chinese medicine spray for treating rhinitis. Background technique [0002] Rhinitis is a very common inflammation of the nasal mucosa and submucosal tissue, generally caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. Symptoms such as hyperplasia, atrophy, or necrosis are clinically manifested as nasal congestion, bleeding, excessive nasal discharge, decreased sense of smell, headache, dizziness, loss of appetite, fatigue, memory loss, and insomnia. [0003] At present, there are many methods for clinically treating rhinitis, but there are various disadvantages, such as surgical treatment of rhinitis, which treats the symptoms but not the root cause, brings pain to the patient, and reduces the quality of life of the patient; Western medicine antibiotics and antihistamines, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/12A61P11/02
CPCA61K9/0043A61K35/10A61K36/28A61K36/51A61K36/538A61K36/74A61K36/899A61K2300/00
Inventor 李宝才杨泊涛张惠芬
Owner KUNMING UNIV OF SCI & TECH
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