Medicine composition for treating osteoporosis and preparation method thereof

Abstract

The invention discloses a medicine composition for treating osteoporosis and a preparation method thereof. The medicine composition is prepared from collagen, chondroitin sulfate sodium salt, calcium carbonate, rhizoma drynariae extract, kudzu vine root extract, D-glucosamine hydrochloride and pseudo-ginseng. The medicine composition can be used for treating the pathogenesis, namely destruction of bone microstructure, of osteoporosis, is capable of solving the problem of bone density abnormality and radically preventing and treating osteoporosis; and the medicine composition can be used for relieving symptoms of ostealgia of osteoporosis patients, healing of bone fracture can be promoted, and the living quality of osteoporosis patients can be improved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to a pharmaceutical composition for treating osteoporosis by repairing bone microstructure and increasing bone density and a preparation method thereof. Background technique [0002] With the entry of an aging society and the rapid increase of the elderly population, osteoporosis has become a serious public health problem. At present, there are more than 1.5 million osteoporosis-related fractures in the United States every year, while the elderly population over 60 years old in my country is 132 million, and the number of osteoporosis patients is about 90 million. It can be seen that the diagnosis and treatment of osteoporosis has become a top priority. [0003] The World Health Organization defines osteoporosis as a systemic bone disease characterized by low bone mass and destruction of bone microarchitecture, resulting in increased bone fragility and susceptibility to ...

AI Technical Summary

Problems solved by technology

Estrogen is the drug of choice for preventing and treating postmenopausal osteoporosis, but it can easily cause increased leucorrhea, breast swelling, and irregular uterine bleeding, with an incidence rate of about 10%. It has been reported that estrogen can increase the incidence of breast cancer and uterine cancer , so there are serious security risks, and should be used with caution

In addition to estrogen, calcium preparations and other chemical drugs used to prevent and treat osteoporosis cannot improve the destruction of bone microstructure, and the side effects are serious, and the purpose of long-term use to prevent and treat osteoporosis cannot be achieved

Under the guidance of TCM theory, use traditional Chinese medicine (such as calcium-containing Chinese patent medicine Longmu Zhuanggu Granules, Zhuanggujiewan Pills, Pearl Niuhuang Powder, Zhenzhu Zhenjing Pills, Wuji Baifeng Pills, Cynomorium Gujing Dan, Zhuhuang Powder, Pearl layer tablets, Pearl Babao Dan, etc.) to prevent and treat osteoporosis, the safety is relatively high, but because traditional Chinese medicine is the regulation of systemic functions, the onset of effect is slow, the patient's compliance is not good, and the purpose of preventing and treating osteoporosis cannot be achieved

There are also pharmaceutical compositions for the prevention and treatment of osteoporosis by several methods simultaneously on the market. For example, the "Manual for the Prevention and Treatment of Osteoporosis in the Chinese Population 2013 Edition" proposes to choose calcium preparations, estrogen receptor modulators, anabolic hormone preparations, Calcium preparations, active vitamin D3 preparations, vitamin preparations, ipropoxyflavone preparations and other preparations are adjusted, but the problem is still the absorption and metabolism of calcium, which has no effect on bone microstructure, so good curative effect cannot be obtained

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