Degradable bacteriostatic medical dressing and preparation method thereof

Abstract

The invention brings forward a degradable bacteriostatic medical dressing and its preparation method. By adjusting ratio of sebacic acid to glycerin and filling-in a monomer, the prepared dressing has good surface property, degradation property and antibacterial property. During the synthesis process, a catalyst or a solvent is not added. Thus, negative effects of a catalyst or a solvent on biocompatibility of the dressing are avoided. The dressing acts on a wounded part and absorbs a percolate of the wound so as to achieve the purpose of self-degradation and medicine-releasing. Meanwhile, appropriate humidity of the wound is maintained. The dressing also has good tissue reactivity, and nano-silver has effects of high permeability, bacteriostasis, sterilization, repairing and regeneration, no drug resistance and the like and helps protect the wound and isolate the invasion of outside bacteria. The dressing is transparent and is easy to observe the healing condition of a wound. Medicines will not be left in human body, and it is safer. As quality declines linearly during the degradation process, the original geometrical shape, surface integrity and mechanical strength can be maintained.

Description

technical field [0001] The invention relates to a dressing and a preparation method thereof, in particular to a degradable antibacterial medical dressing and a preparation method thereof, belonging to the technical field of medical equipment. Background technique [0002] The most widely used biodegradable materials in the field of biomedicine are polyglycolide, polylactide and their copolymer poly(DL-lactide-coglycolide), etc., for example, in July 1988 The Chinese patent "Preparation Method of Polyacrylate Drug Sustained Release Material" published on the 13th with the publication number CN86104141A discloses a drug sustained release material based on polyacrylate, except polyacrylate powder In addition, emulsified monomers, oxides, sugars, salts, and drugs are added, and the synthesis is triggered under a certain irradiation dose, but there are rapid loss of initial mass, loss of mechanical strength, swelling, and significant deformation during the degradation process. s...

AI Technical Summary

Problems solved by technology

[0002] The most widely used biodegradable materials in the field of biomedicine are polyglycolide, polylactide and their copolymer poly(DL-lactide-coglycolide), etc., for example, in July 1988 The Chinese patent "Preparation Method of Polyacrylate Drug Sustained Release Material" published on the 13th with the publication number CN86104141A discloses a drug sustained release material based on polyacrylate, except polyacrylate powder In addition, emulsified monomers, oxides, sugars, salts, and drugs are added, and the synthesis is triggered under a certain irradiation dose, but there are rapid loss of initial mass, loss of mechanical strength, swelling, and significant deformation during the degradation process. shortcoming

[0003] There are also polyurethane foam, hydrogel, alginate fiber, and fabric lamps as dressings, but these materials are difficult to maintain in shape when applied to the affected area, have poor mechanical properties, and have unsatisfactory therapeutic effects on the affected area