34 results about "Implant electrode" patented technology

A method and system for protecting electrode arrays while implanted on a brain including a flexible electrode array including non-penetrating cortical surface microelectrodes, a ceramic layer covering the electrode array and a polymer layer adjacent the ceramic layer, wherein the ceramic layer and the polymer layer hermetically seal the electrode array. The ceramic layer can be configured to exhibit sufficient flexibility to allow the electrode array to be implanted using minimally invasive surgical techniques, while still hermetically sealing the electrode array from a biological environment.

Presented is a system and method for implanting a flexible electrode array in a biological organ. The system includes an electrode implant tool that includes an elongate rod and an electrode implant assembly having a plurality of attachment members. The electrode implant assembly further includes a ring member connected to each of the attachment members. A variable magnetic field generator is arranged in the ring member. The system uses electromagnetic force to temporarily strengthen the flexible electrodes allowing the penetration into the brain.

Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body. Temperature sensors positioned to measure the temperature at the electrode elements are also implanted, along with a circuit that collects temperature measurements from the temperature sensors. In some embodiments, an AC voltage generator configured to apply an AC voltage across the plurality of sets of electrode elements is also implanted within the person's body.

In an electrostatic chuck which electrostatically adsorbs and fixes a workpiece placed on a placement surface by applying a voltage to an electrode implanted therein, the placement surface has a concavo-convex structure comprising a plurality of convex portions two-dimensionally spaced apart from each other at a predetermined pitch and flat concave portions between the convex portions, and the convex portions comprise: flat portions; the substrate is provided with a flat surface which is vertical to the thickness direction of the electrostatic chuck and is uniform in height; and an inclined portion located around the flat portion, the height of the inclined portion decreasing from the flat portion toward the recessed portion, and the inclination angle of the upper surface of the inclined portion with respect to the thickness direction of the electrostatic chuck being 65-84 degrees.

The present invention relates to a deep brain electrical stimulation system, and more particularly to a neural electrical stimulation system capable of being equipped with multiple electrodes, comprising a pulse generator, an extension wire, an electrode, and a fixing device, wherein the pulse generator is a multi-channel, multi-contact pulse generator, the extension wire is connected to the multi-channel, multi-contact pulse generator via contacts, the electrode is connected to the extension wire, and the fixing device is used to fix the electrode during use. The electrical stimulation system of the present invention can adjust the matching relationship between the number of pulse contacts and the number of electrodes according to the requirements of system precision, thereby achieving multi-channel, multi-pulse electrical stimulation output; the present invention also adjusts the structure of the extension wire so that, while the number of pulse contacts remains unchanged, more electrodes can be added as needed, thereby meeting the requirements of more complex electrode stimulation.

A patient-specific frequency mapping procedure, a fitting system for carrying out said procedure and computer program product for a cochlear implant or an electric-acoustic stimulation device having an electrode array that has been implanted into the cochlea of said patient is disclosed.

The invention relates to the technical field of metal material preparation, in particular to a tantalum-tungsten-based nano composite target material and a preparation method thereof. The method comprises the following steps: smelting a high-purity tantalum block and a high-purity tungsten block, and casting to obtain a tantalum-tungsten prealloy cast ingot; the tantalum-tungsten pre-alloy cast ingot is subjected to atomization powder making, and Ta-W alloy powder is obtained; the Ta-W alloy powder is mixed with a nano carbon material, and TaW-C mixed powder is obtained; and the TaW-C mixed powder is subjected to magnetic field assisted sintering, grain oriented growth is induced, aftertreatment is conducted, and the tantalum-tungsten-based nano composite target material is obtained. The magnetic field assisted sintering adopts a one-way static magnetic field along the direction vertical to the target surface, and the magnetic field intensity is 2-10T. According to the preparation method, the Ta-W-based nano composite target material with high density, uniform tissue and texture orientation can be prepared, and the deposited film has the characteristics of low stress, high flexibility and the like, and meets the use requirements of a flexible implanted electrode.

A system for implanting an electrode wire (1) is configured for implanting the electrode wire (1) into a brain of an organism, and includes an implantation apparatus (100), a first light source (410), a second light source (420), a first camera (430), a second camera (440), a brain surface camera (450), and a processing apparatus, wherein the implantation apparatus is provided with an implantation movement mechanism that is configured to enable the implantation apparatus (100) to implant the electrode wire (1) at different angles in different orientations.

The present invention discloses a device and method for monitoring cerebral stroke based on non-contact electrical impedance imaging and current focusing. The device is composed of a non-contact current focusing sensor, an electrode switching module, a data acquisition module and an image reconstruction host computer. The non-contact current focusing sensor includes a focusing electrode layer, a detection electrode layer and two insulating layers. Among them, the focusing electrode is used to achieve a current focusing effect, thereby improving the detection depth and sensitivity of the signal; the detection electrode is responsible for obtaining the detection current containing brain electrical impedance information. The image reconstruction host computer is used to achieve image reconstruction and obtain real-time images and quantitative parameters of cerebral stroke. The present invention has the advantages of being non-contact, wearable, safe and friendly, highly sensitive, low cost, and having a fast imaging speed. It is suitable for scenarios such as homes, clinics, ambulances, etc. that require rapid diagnosis or real-time monitoring and are not covered by equipment such as CT / MRI, and avoids the measurement requirements of existing electrical impedance imaging equipment where patients need to shave their heads or implant electrodes.

The current invention relates to a flexible electrode comprising a porous flexible substrate material having a first surface and a second surface diametrically opposed to the first surface; at least one through hole in the porous flexible substrate material, where the at least one through hole extends from the first surface to the second surface, the at least one through hole having an internal surface; a conductive material attached to the first and second surfaces of the porous flexible substrate material, wherein: the at least one through hole is formed such that a first entry hole, having a first entry hole diameter, in the first surface has a larger diameter than a corresponding second entry hole in the second surface, or vice versa, such that the internal surface of the through hole is tapered; the conductive material is also attached to the internal surface of the at least one through hole to provide a continuous conductive film attached to the first and second surfaces, where the first and second surfaces are conductively connected by the conductive material in the at least one through hole; and the conductive material penetrates into the porous flexible substrate to form a mechanical interlock between the conductive material and the porous flexible substrate.

The application provides a method and device for determining the position of an implanted electrode in an MR image, the method comprising: obtaining an MR image of a human body after an electrode is implanted; performing binary processing on the MR image to obtain a binary image; extracting the coordinates of voxels with a value of 1 in the binary image to obtain dot array data, performing principal component analysis on the dot array data to obtain principal component values in multiple dimensions; weighting principal component images in multiple dimensions formed by the principal component values in multiple dimensions to obtain a weighted image; extracting a skeleton image from the weighted image; determining a straight line where the electrode is located from the skeleton image; performing dilation on the straight line and performing coincidence calculation with the binary image or the weighted image, and determining the maximum connected region according to the calculation result; and determining the position of the electrode based on the end points of the maximum connected region.

A system may include a signal generator configured to be in electrical communication with at least one implantable electrode. A system may include a controller configured in electrical communication with the signal generator, wherein the controller is configured to cause the signal generator to generate a first electrical signal configured to cause partial or full block of action potential conduction and / or initiation in an off-target neural component of a first target electrically excitable tissue. The controller may be further configured to cause the signal generator to generate a second electrical signal having a shorter pulse width than the first electrical signal. The second electrical signal can be configured to activate an on-target neural component of a second target electrically excitable tissue.

Disclosed is a neural stimulation system comprising: an implantable device for controllably delivering neural stimuli, and a processor. The device comprises: a pulse generator configured to deliver neural stimuli via one or more stimulus electrode configurations (SECs), each SEC comprising one or more stimulation electrodes of an implanted electrode array, to a neural pathway of a patient, the neural stimuli being configured to evoke neural responses from the neural pathway; and a control unit configured to control the pulse generator to deliver neural stimuli via an SEC of the one or more SECs. The processor is configured to: select, from a predetermined ranked list of possible SECs associated with a predetermined first location on the electrode array, the first possible SEC in rank order that does not contain an unusable electrode; and instruct the control unit to control the pulse generator to deliver the neural stimuli via the selected SEC.

Systems for facilitating electrical stimulation within a patient's brain and of recording electrical activity within a patient's brain during the implantation of electrode leads in the patient's brain are described. The systems include a modified operating room (OR) cable and / or a sensing adapter that provide electrical connections with the electrode lead(s) and also provide electrical connections to off-lead electrodes that may be configured in electrical contact on the patient's body remote from the electrodes of the electrode lead(s). The off-lead electrodes may be reference electrodes, for example.

The invention discloses a multi-channel multi-mode active electrode integrated nerve probe chip for an implantable brain-computer interface, which comprises a non-implantable circuit part and an implantable electrode part, wherein the non-implanted circuit part integrates a multi-channel electroneurographic signal detection front end, a chemical signal detection front end, a multi-bit adjustable stimulation circuit, a reconfigurable switch array and digital control logic; the implantable electrode part is of a silicon needle structure, electrical electrodes and chemical electrodes are longitudinally distributed on the surface of the implantable electrode part, and dynamic gating and closed-loop regulation and control are supported. Through the electrode-circuit integrated design, the multi-mode function of synchronous high-precision detection and electrical stimulation output of the electroneurographic signals and the chemical signals is achieved, the problems that in the prior art, the mode is single, and the integration degree is low are solved, and the device has the advantages of being high in channel density and low in noise; 5 [mu] Vrms) and a fast closed-loop response (lt; the method is suitable for acute and long-term brain science research and nerve disease treatment.

The application relates to the technical field of electroencephalogram data processing, and discloses a stereotactic electroencephalogram electrode contact calibration method and device. The application can clearly and accurately distinguish discrete electrode contact coordinates. Even in the case that the implanted electrode is severely curved or deformed, the center coordinates of the electrode contact area can still be accurately positioned. In the case that imaging is relatively fuzzy and adjacent contacts are difficult to distinguish, the application still has accurate distinguishing ability. In addition, the application can automatically segment different electrodes, independently determine the spatial axis and target point direction of each electrode, and calculate the marking path of the electrode contact. The position and direction of the electrode do not need to be manually marked by a person, and the operation process is convenient. Therefore, the application has the ability to completely, accurately, comprehensively and efficiently complete the electrode calibration work which needs to be manually or semi-automatically completed by a large number of manual interventions in the past, and the application further embodies the characteristics of full automation, high precision and strong flexibility.

The application provides a multi-conducting elastic implant electrode and a preparation method thereof. The multi-conducting elastic implant electrode comprises an electrode body, the electrode body comprises a plurality of electrode segments, each electrode segment comprises an electrode ring, a clamping column and a connecting column, the electrode ring is sleeved outside the connecting column, the plurality of electrode segments are arranged, the clamping column and the connecting column are sequentially and alternately arranged and fixedly connected, two adjacent clamping columns clamp the electrode ring, and the electrode ring and the clamping column are in sealed arrangement; the clamping column is provided with a through hole penetrating through two end surfaces; each electrode ring is electrically connected with a wire, free ends of the wires pass through the through hole and are located on the same side of the electrode body. The application can improve the flexibility of the implant electrode as a whole and can effectively improve the adaptability of the product implanted in the body.

The invention discloses a device for acquiring a bio-electricity signal and equipment for acquiring the bio-electricity signal, which are used for implanting an electrode under an epidermal layer to acquire the bio-electricity signal. According to the technical scheme, the device for obtaining the bio-electricity signals comprises an implanted electrode, a power supply, a data output unit and a control circuit, the implanted electrode comprises a first electrode and a second electrode which can collect the bio-electricity signals, the first electrode and the second electrode are connected in an insulated mode, and the power supply is connected with the data output unit. The power supply can provide electric energy for the first electrode, the second electrode, the data output unit and the control circuit, the control circuit is suitable for processing bio-electricity signals collected by the first electrode and the second electrode, and the data output unit is suitable for wirelessly transmitting the processed bio-electricity signals to the outside.

The present disclosure relates to a system for assisting in implanting an electrode wire, comprising: an electrode wire fixing apparatus; a guide needle fixing apparatus; a movement mechanism; a first camera, arranged on a first side of a plane and towards a metal part, the first camera having a first optical path; a second camera, arranged on the first side of the plane and towards the metal part, the second camera having a second optical path at an angle to the first optical path; and a processing apparatus, configured to identify a relative position of the end of a guide needle to a through hole based on images shot by the first camera and the second camera, and control the movement mechanism to drive the electrode wire fixing apparatus and / or the guide needle fixing apparatus to move, so that the end of the guide needle is aligned with the through hole. The present disclosure further relates to a method for guiding an electrode wire.

The invention discloses a flexible implantable electrode and a preparation method thereof, and a detection system. The flexible implantable electrode comprises a flexible substrate; the graphitization-like carbon film is located on the flexible substrate, the graphitization-like carbon film is provided with a working electrode pattern, a reference electrode pattern and a counter electrode pattern, and the graphitization-like carbon film is formed by pre-mixing graphene oxide and a polymer precursor and then coating the mixture on the first substrate for carbonization reaction; the catalyst layer is positioned on the working electrode pattern; the enzyme recognition layer is positioned on the catalytic layer; the selective membrane is positioned on the enzyme recognition layer; the ink layer is positioned on the reference electrode pattern; and the salt bridge film layer is positioned on the ink layer. The flexible implantable electrode disclosed by the invention has good biocompatibility, long-term stability, mechanical flexibility and implantation adaptability; the thickness and the structure uniformity are good, and large-scale preparation is facilitated.

The present invention relates to an electrode, which is an in vivo insertable electrode, including a substrate, an electrically conductive layer formed on the substrate, a platinum black layer formed on the electrically conductive layer, a self-assembled monolayer (SAM) formed on the platinum black layer, and a lubricant layer formed on the SAM, a method of manufacturing the electrode, and a medical device including the electrode. The in vivo insertable electrode according to the present invention provides excellent electrical properties such as low impedance. Further, it shows that friction with tissue occurring when the electrode is inserted is reduced, and trauma during insertion and an immune rejection response after insertion is suppressed. Further, in the long term, it is possible to detect signals with high sensitivity throughout the entire period by preventing bioadhesion of in vivo cells, such as immune cells, and other proteins.

An apparatus includes at least one electrical conduit extending along a longitudinal axis and at least one electrode. The at least one electrode includes a portion configured to be in electrical communication with a portion of tissue and / or bodily fluid of a recipient. The at least one electrode further includes a flexure affixed to and in electrical communication with the at least one electrical conduit. The portion and the flexure are unitary with one another. The flexure is configured to flex in response to compressive and / or tensile forces applied to either the at least one electrical conduit or the at least one electrode

A method and system for protecting electrode arrays while implanted on a brain including a flexible electrode array including non-penetrating cortical surface microelectrodes, a ceramic layer covering the electrode array and a polymer layer adjacent the ceramic layer, wherein the ceramic layer and the polymer layer hermetically seal the electrode array. The ceramic layer can be configured to exhibit sufficient flexibility to allow the electrode array to be implanted using minimally invasive surgical techniques, while still hermetically sealing the electrode array from a biological environment.

Systems for facilitating electrical stimulation within a patient's brain and of recording electrical activity within a patient's brain during the implantation of electrode leads in the patient's brain are described. The systems include a modified operating room (OR) cable and / or a sensing adapter that provide electrical connections with the electrode lead(s) and also provide electrical connections to off-lead electrodes that may be configured in electrical contact on the patient's body remote from the electrodes of the electrode lead(s). The off-lead electrodes may be reference electrodes, for example.

In one embodiment, a device includes a housing configured to be implanted on or within a body of a recipient; and at least one chamber within the housing, the at least one chamber configured to contain a fluid. The apparatus further includes at least one barrier configured to separate the at least one chamber from tissue and / or body fluid of the recipient. The at least one barrier is configured to allow electrical charges, electrons, ions, and / or predetermined molecules to be delivered through the at least one barrier and to prevent at least one organic species from the tissue and / or body fluid from being delivered into the at least one chamber. The device also includes at least one electrode within the housing and spaced apart from the at least one barrier. The at least one electrode is configured to be in electrical communication with fluid within the at least one chamber.

The present disclosure relates to a system for assisting in implanting an electrode wire, comprising: an electrode wire fixing apparatus; a guide needle fixing apparatus; a movement mechanism; a first camera, arranged on a first side of a plane and towards a metal part, the first camera having a first optical path; a second camera, arranged on the first side of the plane and towards the metal part, the second camera having a second optical path at an angle to the first optical path; and a processing apparatus, configured to identify a relative position of the end of a guide needle to a through hole based on images shot by the first camera and the second camera, and control the movement mechanism to drive the electrode wire fixing apparatus and / or the guide needle fixing apparatus to move, so that the end of the guide needle is aligned with the through hole. The present disclosure further relates to a method for guiding an electrode wire.

The application discloses a cochlear implant simulation fast integration test method and system, wherein the system comprises an upper computer installed with a fast integration test system software, an integration tester, a salinity tester, a debugging box, a synchronization signal line, a speech processor, an implant, an electrode line and a serial port line. The upper computer configures the integration tester to collect parameters, generate stimulation and send, receive collected data, calculate the salinity impedance, the implant electrode impedance, the amplitude symmetry ratio and the charge symmetry ratio of the electrode stimulation signal; the integration tester receives the synchronization signal, transmits, collects and amplifies the data; the salinity tester tests the salinity concentration of the implant; the debugging box converts the instruction sent by the upper computer into a signal acceptable by the speech processor, and simultaneously transmits the synchronization signal to the integration tester through the synchronization signal line. The application reduces the risk of cochlear implant electrode stimulation anomaly, can realize pre-implantation troubleshooting, and is convenient for post-implantation clinical research.

The invention discloses a balloon spot surface implantation electrode device and a signal transmitting method thereof in the field of vestibular function repair.The balloon spot surface implantation electrode device comprises a base plate, an inner electrode array, an outer electrode array and micro-grain marked lines, the inner electrode array and the outer electrode array are arranged in the base plate, the base plate comprises a base plate handle and a base plate racket, the edge of the base plate racket is in close contact with the inner wall of a balloon inner membrane, and the micro-grain marked lines are arranged on the base plate handle. The lower plane is in close contact with otolith on the surface of a sacculus spot, the base plate handle penetrates through the sacculus shell, the micro-grain marked line is located on the surface of the base plate or in the base plate, and the micro-grain marked line coincides with micro-grains on the surface of the sacculus spot in position and is the same as the micro-grains on the surface of the sacculus spot in shape. An electronic signal passes through the implanted electrode and is transmitted to the surface of a balloon spot to stimulate sensory cilia cells in the balloon, so that an artificial otolith organ feeling is generated.