61 results about "Implant electrode" patented technology

Disclosed herein are systems, devices, and methods for implanting electrodes within a cerebral vessel of a subject. For example, disclosed are various types of implantable electrode arrays, stents carrying electrode arrays, delivery devices for implantable electrode arrays, electrical interfaces for an implantable electrode array, connector lead cable assemblies for an implantable electrode array, and methods of delivering and deploying implantable electrode arrays.

The invention provides an artificial cochlea which comprises an implant and an extracorporeal machine, the implant and the extracorporeal machine both adopt a magnet-free design, the extracorporeal machine is configured to receive a sound signal and transmit the sound signal to the implant after first processing, the implant is configured to perform second processing on the sound signal after first processing, and the implant is configured to perform second processing on the sound signal after second processing. The auditory neuron is stimulated by implanting an electrode; the in-vitro machine comprises an electrode array, the electrode array comprises a base and a plurality of electrode assemblies, and the electrode assemblies are inserted into a target scalp area in a semi-intrusive mode so that at least part of the in-vitro machine can be fixed to the target scalp area; wherein the implant is arranged on the inner side of the target scalp area, and the extracorporeal machine is arranged on the outer side of the target scalp area. And due to the non-magnet design, the artificial cochlea can improve the use experience of the user.

A method and system for protecting electrode arrays while implanted on a brain including a flexible electrode array including non-penetrating cortical surface microelectrodes, a ceramic layer covering the electrode array and a polymer layer adjacent the ceramic layer, wherein the ceramic layer and the polymer layer hermetically seal the electrode array. The ceramic layer can be configured to exhibit sufficient flexibility to allow the electrode array to be implanted using minimally invasive surgical techniques, while still hermetically sealing the electrode array from a biological environment.

An example method for electrically stimulating a subject includes creating a plurality of circuits using an implantable electrode placed within a subject, transmitting a signal at a first frequency through a first circuit of the plurality of circuits, and generating a first electric field, and transmitting a signal of a second frequency through a second circuit of the plurality of circuits, and the second circuit generating a second electric field. The implantable electrode is placed in a substantially linear configuration along a same axis such that the first electric field and the second electric field are in an axially biased configuration, and the first electric field and the second electric field interfere with each other in an overlapping region to produce a beat signal.

The embodiment of the invention discloses an electrode direction recognition method, device and equipment, a medical system, a medium and a product, and the method comprises the steps: obtaining an original CT image and an X-ray plane image which comprise a target object; identifying electrode position information of a target electrode in the original CT image, and replacing a region at least comprising the target electrode in the original CT image with a corresponding electrode template according to the electrode position information to obtain a reference electrode template CT image; the target electrode is a directional electrode implanted in a target object; adjusting the electrode direction of an electrode template in the reference electrode template CT image, and obtaining CT image coronal projection images corresponding to the reference electrode template CT image in a plurality of electrode directions; and according to the similarity between the CT image coronal projection image and the X-ray plane image in each electrode direction, determining the electrode direction of the directional electrode implanted into the target object. According to the embodiment of the invention, the orientation of the implanted electrode can be automatically identified.

Presented is a system and method for implanting a flexible electrode array in a biological organ. The system includes an electrode implant tool that includes an elongate rod and an electrode implant assembly having a plurality of attachment members. The electrode implant assembly further includes a ring member connected to each of the attachment members. A variable magnetic field generator is arranged in the ring member. The system uses electromagnetic force to temporarily strengthen the flexible electrodes allowing the penetration into the brain.

Systems and methods for cortical mapping to optimize placement of a neural interface in a brain of a patient are provided. A method for cortical mapping of a brain of a patient includes implanting an electrode array proximate to the brain of the patient at a position. The electrode array may include a flexible substrate and a plurality of electrodes arranged on the flexible substrate. The method may further include monitoring and electrophysiological mapping of the brain by causing the patient to perform, attempt to perform, or imagine performing an action over a period of time, recording, via the electrode array, neural activity exhibited by the patient in response to the action or imagined action performed by the patient, decoding the neural activity to determine a correspondence between the neural activity and the action, and determining a level of confidence, wherein the level of confidence is based on the correspondence.

The present invention belongs to the field of brain-computer interface, and specifically relates to an ECoG electrode and a preparation method thereof. The implantable electrode of the present invention includes a flexible support layer, an electrode metal layer and a packaging layer, wherein the electrode metal layer includes an electrode contact array area, a pad area and a conductive wire; the electrode contact array area contains one or more electrode contacts, and the pad area contains one or more solder joints; each of the electrode contacts and a corresponding solder joint is connected by a conductive wire to form a connection path, and different connection paths are electrically isolated from each other. The present invention sets different materials on the exposed surfaces of the electrode contacts and solder joints, so that different materials can give full play to their respective advantages, which not only optimizes the electrode performance, but also helps to maintain the consistency of signal transmission. At the same time, the manufacturing process required for the electrode is also relatively simple, the cost is lower, and it is also more environmentally friendly.

Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body. Temperature sensors positioned to measure the temperature at the electrode elements are also implanted, along with a circuit that collects temperature measurements from the temperature sensors. In some embodiments, an AC voltage generator configured to apply an AC voltage across the plurality of sets of electrode elements is also implanted within the person's body.

In an electrostatic chuck which electrostatically adsorbs and fixes a workpiece placed on a placement surface by applying a voltage to an electrode implanted therein, the placement surface has a concavo-convex structure comprising a plurality of convex portions two-dimensionally spaced apart from each other at a predetermined pitch and flat concave portions between the convex portions, and the convex portions comprise: flat portions; the substrate is provided with a flat surface which is vertical to the thickness direction of the electrostatic chuck and is uniform in height; and an inclined portion located around the flat portion, the height of the inclined portion decreasing from the flat portion toward the recessed portion, and the inclination angle of the upper surface of the inclined portion with respect to the thickness direction of the electrostatic chuck being 65-84 degrees.

According to the semiconductor device assembling equipment, a notch is formed in the closed end of a sleeve, when an electrode cell is implanted, a feeding assembly pushes the sleeve into a jig hole of a positioning seat arranged on a rotating disc assembly, a pressing block presses the sleeve in the jig hole tightly under the action of a reed, and then the sleeve is inserted into the positioning seat; the control device controls the rotating disc assembly to rotate the pipe sleeve on the positioning base to the right lower portion of the lower guide groove, a groove opening in the pipe sleeve corresponds to the lower guide groove, the sliding table air cylinder drives the guide plate to move downwards, the trigger elastic piece retracts into the trigger through hole under the action of the trigger electrode, the lower guide groove is conducted, and the pipe sleeve is driven to move downwards. The embedded anode core is implanted into the casing pipe through the notch in the pipe sleeve, the control device controls the rotating disc assembly to rotate by one station to the discharging mechanical arm, discharging is completed through the discharging mechanical arm, the electrode cell is directly embedded at the tail end of the casing pipe, and therefore when packaging is conducted again, the tail end of the casing pipe is directly packaged.

The present invention relates to a deep brain electrical stimulation system, and more particularly to a neural electrical stimulation system capable of being equipped with multiple electrodes, comprising a pulse generator, an extension wire, an electrode, and a fixing device, wherein the pulse generator is a multi-channel, multi-contact pulse generator, the extension wire is connected to the multi-channel, multi-contact pulse generator via contacts, the electrode is connected to the extension wire, and the fixing device is used to fix the electrode during use. The electrical stimulation system of the present invention can adjust the matching relationship between the number of pulse contacts and the number of electrodes according to the requirements of system precision, thereby achieving multi-channel, multi-pulse electrical stimulation output; the present invention also adjusts the structure of the extension wire so that, while the number of pulse contacts remains unchanged, more electrodes can be added as needed, thereby meeting the requirements of more complex electrode stimulation.

A patient-specific frequency mapping procedure, a fitting system for carrying out said procedure and computer program product for a cochlear implant or an electric-acoustic stimulation device having an electrode array that has been implanted into the cochlea of said patient is disclosed.

The invention relates to the technical field of metal material preparation, in particular to a tantalum-tungsten-based nano composite target material and a preparation method thereof. The method comprises the following steps: smelting a high-purity tantalum block and a high-purity tungsten block, and casting to obtain a tantalum-tungsten prealloy cast ingot; the tantalum-tungsten pre-alloy cast ingot is subjected to atomization powder making, and Ta-W alloy powder is obtained; the Ta-W alloy powder is mixed with a nano carbon material, and TaW-C mixed powder is obtained; and the TaW-C mixed powder is subjected to magnetic field assisted sintering, grain oriented growth is induced, aftertreatment is conducted, and the tantalum-tungsten-based nano composite target material is obtained. The magnetic field assisted sintering adopts a one-way static magnetic field along the direction vertical to the target surface, and the magnetic field intensity is 2-10T. According to the preparation method, the Ta-W-based nano composite target material with high density, uniform tissue and texture orientation can be prepared, and the deposited film has the characteristics of low stress, high flexibility and the like, and meets the use requirements of a flexible implanted electrode.

An implantable electrode device is provided comprising a first layer and a second layer, the second layer being on top of the first layer and including at least one electrode contact. The at least one electrode contact is exposable to a nerve of a nervous tissue of a human or of an animal. A connecting means electrically connects the electrode contact, where the connecting means is made up of at least one conducting wire, and the conducting wire is arranged within the first layer and is fixed to the electrode contact. Also provided is a method for forming an implantable electrode device.

A system for implanting an electrode wire (1) is configured for implanting the electrode wire (1) into a brain of an organism, and includes an implantation apparatus (100), a first light source (410), a second light source (420), a first camera (430), a second camera (440), a brain surface camera (450), and a processing apparatus, wherein the implantation apparatus is provided with an implantation movement mechanism that is configured to enable the implantation apparatus (100) to implant the electrode wire (1) at different angles in different orientations.

A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

The present invention discloses a device and method for monitoring cerebral stroke based on non-contact electrical impedance imaging and current focusing. The device is composed of a non-contact current focusing sensor, an electrode switching module, a data acquisition module and an image reconstruction host computer. The non-contact current focusing sensor includes a focusing electrode layer, a detection electrode layer and two insulating layers. Among them, the focusing electrode is used to achieve a current focusing effect, thereby improving the detection depth and sensitivity of the signal; the detection electrode is responsible for obtaining the detection current containing brain electrical impedance information. The image reconstruction host computer is used to achieve image reconstruction and obtain real-time images and quantitative parameters of cerebral stroke. The present invention has the advantages of being non-contact, wearable, safe and friendly, highly sensitive, low cost, and having a fast imaging speed. It is suitable for scenarios such as homes, clinics, ambulances, etc. that require rapid diagnosis or real-time monitoring and are not covered by equipment such as CT / MRI, and avoids the measurement requirements of existing electrical impedance imaging equipment where patients need to shave their heads or implant electrodes.

Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body, with temperature sensors positioned to measure the temperature at the electrode elements also being implanted.

The present invention provides a universal connector for implanted electrodes, a device and an injection voltage testing device. The universal connector for implanted electrodes includes a plurality of conductive terminals. When a columnar implanted electrode is installed in the universal connector, some of the conductive terminals will contact the electrode contacts to achieve electrical connection. Since each conductive terminal is connected to a connecting wire, and the other end of the connecting wire is set as a free end, the tester can connect the connecting wires of all the conductive terminals connected to the same electrode contact to the same test channel to achieve the test of the electrode contact. Due to the different specifications of the columnar implanted electrodes, the conductive terminals that achieve electrical connection with the electrode contacts are also different. In order to achieve the universality of the connection of different specifications of implanted electrodes, the tester can adjust the connection of each connecting wire to the test channel according to the contact situation between the conductive terminal and the electrode contact.

An implantable electrode device for a cochlear implant system includes an elongated electrode array for insertion into a patient's cochlea. A fluid delivery channel is located within the electrode array, parallel to a central longitudinal axis and has at least one fluid delivery port for delivering a lubricant fluid from the fluid delivery channel to an outer surface of the electrode array. The fluid delivery port and the lubricant fluid are configured to create a lubricated area near an outer surface of the electrode array adjacent to the fluid delivery port during insertion of the electrode array into the patient's cochlea to reduce insertion resistance at an adjacent segment of a side wall of the patient's cochlea.

The invention relates to the technical field of electroencephalogram data processing, and discloses an electrode contact calibration method and device for a stereotactic electroencephalogram, which can clearly and accurately distinguish discrete electrode contact coordinates, and even if an implanted electrode is seriously bent or deformed and other irregular conditions, the electrode contact calibration method and device for the stereotactic electroencephalogram can be used for calibrating the electrode contact coordinates of the stereotactic electroencephalogram. The center coordinate of the electrode contact area can still be accurately positioned, and the method still has accurate distinguishing capability for the condition that adjacent contacts are difficult to distinguish due to relatively fuzzy imaging. Besides, different electrodes can be automatically segmented, the space axial direction and the target point direction of each electrode can be autonomously determined, the marking path of the electrode contact is calculated, the positions and the directions of the electrodes do not need to be manually marked, and the operation process is convenient and fast. Therefore, the electrode calibration device has the capability of completely, accurately, comprehensively and efficiently completing the electrode calibration work which needs to be manually or semi-automatically completed by manual intervention in the past, and the characteristics of full automation, high precision and high flexibility of the electrode calibration device are better embodied.

The current invention relates to a flexible electrode comprising a porous flexible substrate material having a first surface and a second surface diametrically opposed to the first surface; at least one through hole in the porous flexible substrate material, where the at least one through hole extends from the first surface to the second surface, the at least one through hole having an internal surface; a conductive material attached to the first and second surfaces of the porous flexible substrate material, wherein: the at least one through hole is formed such that a first entry hole, having a first entry hole diameter, in the first surface has a larger diameter than a corresponding second entry hole in the second surface, or vice versa, such that the internal surface of the through hole is tapered; the conductive material is also attached to the internal surface of the at least one through hole to provide a continuous conductive film attached to the first and second surfaces, where the first and second surfaces are conductively connected by the conductive material in the at least one through hole; and the conductive material penetrates into the porous flexible substrate to form a mechanical interlock between the conductive material and the porous flexible substrate.

The application provides a method and device for determining the position of an implanted electrode in an MR image, the method comprising: obtaining an MR image of a human body after an electrode is implanted; performing binary processing on the MR image to obtain a binary image; extracting the coordinates of voxels with a value of 1 in the binary image to obtain dot array data, performing principal component analysis on the dot array data to obtain principal component values in multiple dimensions; weighting principal component images in multiple dimensions formed by the principal component values in multiple dimensions to obtain a weighted image; extracting a skeleton image from the weighted image; determining a straight line where the electrode is located from the skeleton image; performing dilation on the straight line and performing coincidence calculation with the binary image or the weighted image, and determining the maximum connected region according to the calculation result; and determining the position of the electrode based on the end points of the maximum connected region.

Neurostimulation of a mixed nerve comprising a plurality of nerve fibre types. An implantable electrode array comprising a plurality of electrodes is positioned proximal to the mixed nerve. An electrical stimulus is delivered from at least one nominal stimulus electrode of the implantable electrode array, in accordance with a set of stimulus parameters. A recording of the electrophysiological response evoked by the electrical stimulus is obtained from at least one nominal recording electrode of the implantable electrode array. The recording is analysed by assessing one or more selected characteristics of the recording, and from the observed selected characteristics a level of recruitment of one or more fibre types recruited by the electrical stimulus is identified. The stimulus parameters are refined in a manner to effect selective recruitment of one or more fibre types relative to other fibre types of the mixed nerve.

A system may include a signal generator configured to be in electrical communication with at least one implantable electrode. A system may include a controller configured in electrical communication with the signal generator, wherein the controller is configured to cause the signal generator to generate a first electrical signal configured to cause partial or full block of action potential conduction and / or initiation in an off-target neural component of a first target electrically excitable tissue. The controller may be further configured to cause the signal generator to generate a second electrical signal having a shorter pulse width than the first electrical signal. The second electrical signal can be configured to activate an on-target neural component of a second target electrically excitable tissue.

The present application discloses a test fixture for an implantable electrode wire, comprising a slide rail and a head end slider, an intermediate slider and a tail end slider sequentially arranged on the slide rail; a head end clamping device for fixing the electrode wire is provided on the head end slider, and a tail end clamping device for fixing the electrode wire is provided on the intermediate slider; a tension sensor for measuring the tension on the electrode wire is rigidly connected between the intermediate slider and the tail end slider, and the tension sensor is electrically connected to a control box for measuring the obtained tension value. When the tension value displayed by the control box reaches the required tension value or the moving distance of the tail end slider reaches the required stretching length, the tail end slider is locked on the slide rail and kept for the required time to observe whether the electrode wire is broken or the electrical insulation layer is broken, so as to know whether the electrode wire under test can withstand the tension after implantation, which fills the gap of the implantable electrode wire tension test fixture and has the advantages of simple structure and easy operation.

Disclosed herein are systems, devices, and methods for implanting electrodes within a cerebral vessel of a subject. For example, disclosed are various types of implantable electrode arrays, stents carrying electrode arrays, delivery devices for implantable electrode arrays, electrical interfaces for an implantable electrode array, connector lead cable assemblies for an implantable electrode array, and methods of delivering and deploying implantable electrode arrays.

Disclosed is a neural stimulation system comprising: an implantable device for controllably delivering neural stimuli, and a processor. The device comprises: a pulse generator configured to deliver neural stimuli via one or more stimulus electrode configurations (SECs), each SEC comprising one or more stimulation electrodes of an implanted electrode array, to a neural pathway of a patient, the neural stimuli being configured to evoke neural responses from the neural pathway; and a control unit configured to control the pulse generator to deliver neural stimuli via an SEC of the one or more SECs. The processor is configured to: select, from a predetermined ranked list of possible SECs associated with a predetermined first location on the electrode array, the first possible SEC in rank order that does not contain an unusable electrode; and instruct the control unit to control the pulse generator to deliver the neural stimuli via the selected SEC.

Systems for facilitating electrical stimulation within a patient's brain and of recording electrical activity within a patient's brain during the implantation of electrode leads in the patient's brain are described. The systems include a modified operating room (OR) cable and / or a sensing adapter that provide electrical connections with the electrode lead(s) and also provide electrical connections to off-lead electrodes that may be configured in electrical contact on the patient's body remote from the electrodes of the electrode lead(s). The off-lead electrodes may be reference electrodes, for example.