Apparatus for determining a parameter indicative of the progress of an extracorporeal blood treatment

A processing device and blood processing technology, which is applied in the direction of pharmaceutical equipment, complex mathematical operations, general control systems, etc., can solve problems such as difficult to measure asymptotic values, limit the flexibility of dialysis machine operation, and difficult to interpret signals

Active Publication Date: 2015-01-28
GAMBRO LUNDIA AB
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  • Abstract
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  • Claims
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Problems solved by technology

In other words, throughout the process of changing the conductivity/concentration of the dialysate upstream of the dialyzer or hemofilter and measuring the corresponding change in conductivity/concentration downstream, the control system of the dialysis machine does not allow for implementations that could affect the conductivity or composition of the dialysate. other tasks, thereby limiting the operational flexibility of the dialysis machine
[0021] Furthermore, the method described above is sensitive to artifacts that may be present in the conductivity measured downstream of the dialyzer, which may be caused by several factors (e.g. air bubbles present in the dialysis circuit, activation/deactivation of some actuators such as pumps, etc. , valve open or close, etc.)
[0022] Additionally, it may be difficult to accurately measure ...

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  • Apparatus for determining a parameter indicative of the progress of an extracorporeal blood treatment
  • Apparatus for determining a parameter indicative of the progress of an extracorporeal blood treatment
  • Apparatus for determining a parameter indicative of the progress of an extracorporeal blood treatment

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Embodiment Construction

[0184] Figure 1 to Figure 3 A non-limiting example of an extracorporeal blood treatment device 1 is shown in which the innovative solution of the invention can be implemented. figure 1 is a more schematic diagram of the extracorporeal blood treatment device 1, while figure 2 and image 3 Two possible non-limiting embodiments of the device 1 are shown in more detail.

[0185] The device 1 may be configured to determine a parameter indicative of the effectiveness of the treatment delivered to the patient (hereinafter also referred to as the effectiveness parameter). The validity parameter can be one of the following:

[0186] - the effective dialysis rate (D) of one or more substances of the treatment unit, such as electrolyte or sodium clearance;

[0187] - effective clearance (K) of one or more substances of the treatment unit, e.g. urea clearance;

[0188] - the concentration (Cbin) of the substance in the blood upstream of the blood treatment unit, for example the sod...

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Abstract

An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. The value of the effectiveness parameter is calculated using one or more values representative of the conductivity in the spent dialysate line obtained relying on a mathematical model.

Description

technical field [0001] The present invention relates to a device for determining parameters (called effectiveness parameters) indicative of the progress of extracorporeal blood treatment, in particular purification treatments aimed at alleviating renal insufficiency, such as but not limited to blood Dialysis or hemodiafiltration. Also disclosed is a method of determining said parameter indicative of the progress of extracorporeal blood treatment. This parameter can be, for example, one of the following: [0002] - the concentration of a given solute (for example, sodium) in the blood, [0003] - the actual dialysis rate D or the actual clearance K of the exchanger for a given solute (dialysis rate D and clearance K indicate the purification efficiency of the hemodialyzer or hemofilter used in blood treatment), [0004] - the dialysis dose given after the treatment time t, which can be related to the dimensionless ratio Kt / V according to the studies of Sargent and Gotch, whe...

Claims

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Application Information

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IPC IPC(8): A61M1/16
CPCA61M1/1607A61M1/1617A61M1/16A61M1/1609A61M1/1613A61M2205/3317A61M2205/3324A61M2205/3334A61M2205/3393A61M1/367A61M2209/02G05B13/04G05D7/0617G06F17/10
Inventor F·弗塔那兹F·罗萨蒂A·苏拉切
Owner GAMBRO LUNDIA AB
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