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Dropping pill with algal polysaccharide and flaxseed gum as capsule wall material, and its production technology

A technology of seaweed polysaccharides and dripping pills, which can be used in pill delivery, food forming, medical preparations of non-active ingredients, etc., and can solve problems such as moisture absorption and deterioration of drugs, short validity period, and unqualified quality

Inactive Publication Date: 2015-02-11
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, because gelatin is a protein substance, it has strong hygroscopicity and can transfer the absorbed moisture to the internal medicine, causing the medicine to absorb moisture and deteriorate, resulting in unqualified quality and short validity period.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1 1. The product formula of the seaweed polysaccharide dropping pills of the present invention (composed by weight percentage): 20.0% sodium alginate, 6.0% agar, 8.0% sorbitol and glycerol, 65.0% distilled water and 1% auxiliary The production process of dropping pills is as follows: mix 65.0% distilled water with 8.0% plasticizer and heat to 85°C, slowly mix 20.0% sodium alginate and 6.0% agar under constant stirring Add the mixed glue until a transparent solution is formed, then place it in a sandwich steamer and heat it at 85°C for 20 minutes to melt it into a uniform glue solution. Then use a filter cloth (150 mesh) to filter into the dipping pot (keep it in a water bath), degas at 85°C and 0.5 atm for 10 minutes, and remove the foam on the liquid surface naturally. Pour the prepared glue solution into the glue tank of the dripping pill experiment dripping machine, set the temperature of the curing agent at 15~20°C, the flow rate ratio of the glue solution...

Embodiment 2

[0024] Example 2 1. The product formula of the seaweed polysaccharide capsule of the present invention (composed by weight percentage): 16.0% sodium alginate, 8.0% flax gum, 8% xylitol, 67% distilled water and 1% auxiliary agent; capsule The production process is as follows: mix 67% distilled water and 8% plasticizer and heat to 85°C, slowly add the weighed mixture of 16.0% sodium alginate and 8.0% flax gum under constant stirring until After forming a transparent solution, place it in a sandwich steam pot and heat it at 85°C for 20 minutes to melt it into a uniform glue solution. Then use a filter cloth (150 mesh) to filter into the dipping pot (keep it in a water bath), degas at 85°C and 0.5 atm for 10 minutes, and remove the foam on the liquid surface naturally. Pour the prepared glue solution into the glue tank of the dripping pill experiment dripping machine, set the temperature of the curing agent at 15~20°C, the flow rate ratio of the glue solution and the drug soluti...

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PUM

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Abstract

The invention belongs to the technical field of medicine and health food products research and development, and relates to a formula and a production technology of a dropping pill based on algal polysaccharide. The technology comprises the following steps: 1, weighing 10.0-30.0wt% of algal polysaccharide, 3.0-10.0wt% of flaxseed gum and 2.0-4.0wt% of a plasticizer, putting the above raw materials in 70.0-85.0wt% of deionized water, and maintaining at 85DEG C for 30min to realize algal polysaccharide and flaxseed gum dissolving; 2, degassing at 85DEG C under 0.5atm for 10min, adding the obtained degassed solution into a pill dropping machine, and dropping; and 3, curing dropping pills by a composite curing agent, drying, sorting, and packaging to obtain the dropping pill. The dropping pill has the advantages of reasonable formula, safe eating, drug absorption benefiting, wide source and low price of the raw materials, simple production process, and suitableness for industrialized production.

Description

Technical field [0001] The present invention involves health food and medical capsules, especially a method of producing medicinal drops of pills with seaweed polysaccharides. Background technique [0002] At present, the main raw materials of my country's production of dripping pills are gelatin, and gelatin comes from the bones and skin of animals (pigs, cattle), and its main component is protein.Once this capsule shell is not in place, there may be risk of infectious animal source diseases, heavy metals, etc.The majority of religious believers, Buddhist laymen and vegetarians cannot accept capsule drugs from animals.In addition, because gelatin belongs to protein substances, strong hygroscopicity, and can transfer the absorbed water to internal drugs, which makes the drug moisture and deteriorate, resulting in unqualified quality and short validity period. [0003] With the understanding of plant capsules and the change of the concept of drug use at home and abroad, the market...

Claims

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Application Information

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IPC IPC(8): A61K47/36A61K9/20A23L1/29A23P1/04A23L33/00
Inventor 赖鹏翔刘旭谢卫东黄建军韩静
Owner SHANDONG UNIV
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