Dentin primary coating-washing primary coating agent and method thereof

Abstract

The invention provides a dentin primary coating-washing primary coating agent and a method thereof. The dentin primary coating agent is used for repairing the defect of a tooth body for a stomatological department. The method comprises the following steps: performing pretreatments of primary coating-washing on the surface of the dentin with the dentin primary coating agent, then sticking a repairing body with the dentin by using a self-acid etching bonding agent, wherein the stomatological dentin primary coating-washing primary coating agent contains 60%-99.4% of an alcohol aqueous solution, 0.5%-30% of a weak-acid functional monomer and 0.1%-10% of a matrix metalloproteinase inhibitor. The dentin is mildly demineralized by 10-MDP(muramyl dipeptide) containing weak acid; the degradation of a collagenous fiber is reduced by using the matrix metalloproteinase inhibitor; besides the dentin is pretreated by a primary coating-washing method, so that generated MDP-Ca(Calcium) is more firmly jointed to hydroxyapatite, the bonding strength and the bonding durability of the tooth can be further improved, joining of the tooth and the direct repairing body or the indirect repairing body is firmer and more durable, and the health of the rest tissue of the tooth is protected better.

Description

technical field [0001] The present invention relates to the field of stomatology, in particular to a class of dentin primer-rinse primer (primer) and method (etch-&-rinse approach). It is used to directly or indirectly bond dental restorations such as organic polymer materials, ceramics, metals or other composite materials to defective teeth. Background technique [0002] With the continuous development of social economy and culture, people's aesthetic concept is also constantly improving, and countries all over the world are investing more and more in dental beauty and health. The most important content of dental cosmetic restoration is direct resin filling restoration and indirect resin bonding restoration, and these restoration methods all involve a core problem, that is, the bonding of dentin. In the past two decades, dentin adhesives and bonding technology have developed rapidly, and the bonding effect of dentin has been significantly improved. However, the bonding pr...

AI Technical Summary

Problems solved by technology

The biggest difficulty of dentin bonding technology is that the resin monomer cannot completely penetrate into the gaps in the collagen fibers caused by demineralization, resulting in the resin monomer being easily retained on the surface of the mixed layer

The stability of such dentin bonding interface is poor, and it is easy to cause early fracture

[0005] Nowadays, the acid etching-rinsing or self-etching adhesive systems used in stomatology for dental defect bonding will cause calcium ions in the dentin release, thereby activating matrix metalloproteinases (matrix metalloproteinases, MMPs) in dentin. MMPs are a group of zinc / calcium-dependent proteases that can degrade extracellular matrix under neutral conditions[4], resulting in the degradation of collagen fibers in the bonding mixed layer, affecting the durability of dentin bonding[5]

[0006] In our previous research, we also found that phosphate, the main component of self-etching adhesive, can form with hydroxyapatite or enamel, the main component of teeth Soluble calcium salts and poorly soluble calcium salts [6], however, these soluble calcium salts will reduce the bonding strength of tooth enamel [7]

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