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Alcohol disinfectant

一种消毒剂、乙醇的技术，应用在消毒剂、抗病毒剂、杀生剂等方向，能够解决高度易燃、不呈现杀病毒活性、蒸发级别高等问题

Active Publication Date: 2015-04-29
DR SCHUMACHER
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, commercially available disinfectants with an alcohol content in the range of about 60 wt% or less do not exhibit any virucidal activity against naked viruses such as poliovirus
On the other hand, the large amounts of alcohol necessary to kill naked and enveloped viruses have disadvantages such as high levels of evaporation, possible side effects on applied materials, side effects on the skin, and high flammability, etc.

Method used

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  • Alcohol disinfectant
  • Alcohol disinfectant
  • Alcohol disinfectant

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Preparation of four different test solutions

[0042]

[0043] Table 1: Glucopon 215 UP is an aqueous solution of alkyl polyglucosides and is available from BASF, Ludwigshafen, Germany. If necessary, the pH was adjusted with NaOH solution (45% v / v) (except solution 4). Contents are expressed in wt % (except pH).

[0044] Example 1 shows that the addition of HEDP to an alcoholic disinfectant significantly shortens the time required to kill poliovirus type 1. HEDP had a greater impact on efficacy than phosphonic acid.

Embodiment 2

[0046] Solutions Nos. 3 and 4 of Example 1 were tested at different pH values.

[0047]

[0048] Table 2: each solution of embodiment 1 is carried out the test of different pH values

[0049] Table 2 shows that changing the pH did not have any significant effect on the effectiveness of the disinfectant solution.

Embodiment 3

[0051] Solutions No. 3 and 4 of Example 1 were tested with different concentrations of DMMP (dimethylmethylphosphonate) instead of HEDP (1-hydroxyethane-1,1-diphosphonic acid).

[0052]

[0053] Table 3: DMMP tests performed on the solution of Example 1

[0054] Table 3 shows that phosphonates other than HEDP produced the observed effect of shortening the time required to kill poliovirus type 1.

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Abstract

The invention discloses a virucidal disinfectant or preservative, comprising 45 - 65 wt% of at least one alcohol and 0.05 - 0.5 wt% of at least one phosphonate, and adjusting the pH to between 3 and 10. The disinfectant / preservative can be used for living or nonliving disinfection, and shows activity against a wide range of microorganisms, such as viruses, fungi and / or bacteria, especially naked viruses such as polio virus activity.

Description

technical field [0001] The present invention relates to virucidal disinfectants or antiseptics comprising alcohol and at least one phosphonate. The present invention also relates to the use of said disinfectant / antiseptic for disinfecting living or non-living objects. The disinfectants / antiseptics of the present invention are particularly effective against naked viruses such as polio. Background technique [0002] Viral infections are among the most devastating and feared biological health threats known to man. Some viruses envelope themselves in a modified form in the cell membrane (either the outer or inner membrane surrounding an infected host cell, such as the nuclear membrane or the endoplasmic reticulum), resulting in an outer lipid bilayer called the viral envelope. Influenza viruses and HIV are known to use this approach. The infectivity of most of these "enveloped viruses" depends on their encapsulation. Other viruses do not have this envelope but have a nucleoc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N57/20A01N31/02A01P1/00A01P3/00A61K31/663A61K31/662A61K31/045A61P31/12A61P31/10A61P31/04A61P31/02D06M13/144D06M13/288D06M13/447D06M13/368
CPCA01N31/02A61K31/045A61K31/662A61P31/02A61P31/04A61P31/10A61P31/12Y02A50/30A01N57/20A01N2300/00A61K2300/00A01N25/00A01N25/08A01N25/30
Inventor 埃里克·布鲁克纳博士延斯·舒马赫
Owner DR SCHUMACHER
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